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Stoke Therapeutics Preps IPO to Bring Dravet Syndrome Drug to Clinic

After Stoke Therapeutics closed $90 million in financing last fall, CEO Ed Kaye signaled his biotech would seek more cash through an IPO soon. The preclinical-stage biotech is now officially on a path to the public markets.In paperwork filed late Thursday with the SEC, Bedford, MA-based Stoke set a preliminary $86 million target for its IPO, which will fund its research on drugs to treat rare genetic diseases. The company has applied for a Nasdaq listing under the stock symbol “STOK.”Stoke is d...
Tags: Startups, Ipo, Boston, Trends, Investing, Fda, Epilepsy, Biotech, Life Sciences, Clinical Trials, Biogen, Cold Spring Harbor Laboratory, GW Pharmaceuticals, National blog main, Boston blog main, San Francisco blog main


Boston Tech Watch: Robin, Markforged, Air Force AI & CozyKin

The Air Force and MIT partner on AI research. Meeting room tech raises more dough. “Autopilot” for 3D printers. And robot companies teaming up to fill your next ecommerce order. Read on for more of what went down this week in Boston tech news.—Robin Powered, a Boston startup building workplace desk- and meeting room-booking software, closed a $20 million Series B funding round led by Tola Capital and joined by previous investors Accomplice and FirstMark Capital and new investor Allegion Venture...
Tags: Deals, Startups, Boston, New York City, Trends, Tech, Cisco, Childcare, It, Cybersecurity, Mit, Vc, Materials, Venture Capital, 3d Printers, Ai


Scoop Partners with Bedrock to Bring Carpooling Service to Detroiters

Scoop, the app-based carpooling service headquartered in San Francisco, landed in Detroit this week and will now facilitate rides for residents living in seven Motor City ZIP codes that encompass downtown, Midtown, Corktown, and neighborhoods to the immediate east and west of downtown.When Scoop enters a new market, its approach involves partnering with a local employer to build an initial network of carpoolers made up of both drivers and riders. As other companies sign up to partner with Scoop...
Tags: Startups, Apps, Entrepreneurship, Trends, Tech, Software, Innovation, Mobility, Detroit, Carpooling, Ridesharing, Dan Gilbert, Quicken Loans, National blog main, National top stories, San Francisco blog main


Bio Roundup: Zolgensma Watch, Brain Cancer Blues, Peloton Payout & More

Patients, doctors, family members, and drug-price watchdogs continued to wait for the expected approval of Zolgensma, a Novartis (NYSE: NVS) gene therapy for the rare inherited disease spinal muscular atrophy. Originally developed at a children’s hospital in Ohio, Zolgensma will be a litmus test for the nascent field. If approved this week or next, it would be just the second gene therapy to come to market in the US.Novartis CEO Vas Narasimhan made sure Zolgensma stayed in the headlines. In an ...
Tags: Lawsuit, Scotus, Ipo, Study, Cancer, Value, Trends, Investment, Merck, Fail, Data, Vc, Cholesterol, Regulation, Venture Capital, M&a


Despite Industrial Tech’s Growing Sophistication, US Adoption Lags

This week, Detroit is hosting SME’s RAPID + TCT event, a conference and trade show dedicated to additive manufacturing, with a focus on 3D printing. It’s the first time the conference, which draws attendees from across the world, has been held in Detroit since 2014.Maria Conrado, SME’s senior event manager, says the conference has grown by leaps and bounds as additive manufacturing has been on the upswing. “Automotive companies are increasingly looking at 3D printing as part of the [manufacturi...
Tags: Startups, Internet Of Things, Hardware, Big Data, Cloud Computing, Trends, Tech, Cybersecurity, Software, 3d Printing, Automation, Innovation, Manufacturing, Robotics, Detroit, STEM education


Ideaya and Bicycle Therapeutics IPOs Raise $110M for Cancer Drug R&D

Ideaya Biosciences and Bicycle Therapeutics priced their IPOs late Wednesday, raising a combined $110 million to continue clinical trials of their respective experimental cancer drugs.South San Francisco-based Ideaya raised $50 million. The company priced its offering of 5 million shares at $10 apiece, well below the targeted price range of $13 to $15 per share. Those shares are expected to begin trading Thursday on the Nasdaq under the stock symbol “IDYA.”Lead Ideaya drug IDE196 was originally...
Tags: Deals, Drugs, Cancer, San Francisco, Trends, Investing, Ovarian Cancer, Astrazeneca, Novartis, Biotech, Nasdaq, Life Sciences, Celgene, South San Francisco, Canaan Partners, National blog main


Cala Health Secures $50M to Launch Anti-Tremor Wrist Device

Cala Health announced this week it raised $50 million in a Series C financing that will fund the market introduction of its wristwatch-like device that delivers nerve stimulation as a remedy for tremors of the hands.New investors Novartis, Baird Capital, LifeSci Venture Partners and TriVentures participated in the fundraising round, and were joined by all of the company’s previous investors, including Lux Capital, Lightstone Ventures, Action Potential Venture Capital, dRx Capital, GV—the invest...
Tags: Google, Deals, Startups, Mobile, Wearables, Hardware, Internet, Entrepreneurship, Funding, San Francisco, Trends, Tech, Web, It, Devices, Vc


WI Watchlist: Montage, LÜM, WEDC, Titan Spine, Polco, Swallow & More

A medical device for patients with swallowing disorders gets new life. A music streaming app gets an influx of cash. The state’s economic development agency faces more criticism for its practices. Startups in recruiting tech, medtech, and civic tech strike merger and acquisition deals. Read on for more details about these stories and other recent Wisconsin innovation news.—In an unusually structured deal, the Idea Fund of La Crosse, an early-stage investment firm located in western Wisconsin, s...
Tags: Deals, Startups, Jobs, Trends, Tech, Cms, It, Walgreens, Vc, Software, M&a, Wisconsin, NRC, Life Sciences, Medical Devices, Medtronic


Smart Cities Startups, Upswing, Coder, VanillaSoft & More TX Tech

Let’s catch up with the latest innovation news in Texas.—The Dallas-based Innov8te Smart Cities Incubator has named the six startups in its first program, according to a press release. The startups are using technology to help local governments sync data in currently siloed departments, analytics to help cities measure business and individual tourism, and others. In addition to hosting the startups in the program, Innov8te also features what it calls “Startup City Hall,” a dedicated office for ...
Tags: Startups, Cloud, Texas, Big Data, Funding, Trends, Tech, Investment, Analytics, People, Vc, Artificial Intelligence, Software, Austin, Innovation, Venture Capital


Agrilyst Rebrands as Artemis, Lands $8M for Indoor Farming Software

Agrilyst, an agtech startup that has commercialized software that helps manage indoor farms and greenhouses, is unveiling a new name and additional capital. The company is now called Artemis and it has raised an $8 million Series A round of funding.Astanor Ventures and Talis Capital co-led the investment announced Wednesday. Other investors include New York State’s Empire State Development Fund and iSelect Fund.Indoor farming startups have caught the eyes of some venture capitalists, who have p...
Tags: Deals, Startups, New York, Trends, Investing, It, Software, Venture Capital, Artemis, Agrilyst, National blog main, New York blog main, New York top stories, San Francisco blog main, Talis Capital, AgFunder


With $120M, AlloVir Faces Big Test of Cell Therapy to Fight Infection

In healthy people, viruses are kept in check by the immune system. But for immunocompromised patients, such as those undergoing transplant procedures, a viral infection is potentially deadly. AlloVir is developing a cell therapy intended to control infections while a patient’s immune system recovers.Houston-based AlloVir is preparing its lead candidate for late-stage testing and on Wednesday announced $120 million in financing for the research. Fidelity Management and Research Company led the S...
Tags: Deals, Startups, Texas, Trends, Investing, Houston, Biotech, Baylor University, Life Sciences, Herpes, Clinical Trials, Gilead Sciences, Journal of Clinical Oncology, Fidelity Management and Research Company, Veracyte, National blog main


AI Startup Clinc Snags $52M Series B to Expand Offices, Markets

Ann Arbor, MI-based startup Clinc, which is focused on developing conversational artificial intelligence software for use in chatbots, has raised $52 million in a Series B round, the company announced this week. The round was led by Insight Partners, with participation from DFJ Growth, Drive Capital, and Hyde Park Venture Partners.As part of the deal, Jeff Lieberman, Insight Partners’ managing director, will join Clinc’s board of directors while DFJ Growth’s Randy Glein will join its board of a...
Tags: Startups, Entrepreneurship, Trends, Tech, Vc, Artificial Intelligence, Software, Barclays, Innovation, Venture Capital, Detroit, Dfj Growth, Dfj, Series B, University Of Michigan, Randy Glein


Sebastian Thrun and Udacity Launch New Self-Driving Nanodegree

[Corrected 5/21/19, 11:04 am. See below.] Sebastian Thrun first made his mark on autonomous vehicle development at the dawn of that industry, when he led a Stanford team whose robot car Stanley won the $2 million DARPA Grand Challenge in 2005 by racing driverless through the Mojave Desert for 132 miles.These days, Thrun seems just as excited by another imprint he’s made on the still-forming AV industry—not as a researcher, but as an entrepreneur in online education. Thrun (pictured) says many s...
Tags: Google, Deals, Mobile, Lyft, Uber, Hardware, Talent Gap, Education, Workplace, Internet, Entrepreneurship, Stanford, Funding, San Francisco, Trends, Tesla


Guardicore Raises $60M and Moves US HQ to Boston From San Francisco

US-Israeli cybersecurity startup Guardicore is moving its American headquarters from San Francisco to Boston after hiring a Massachusetts marketing executive and raising a $60 million funding round.The Tel Aviv-based company’s decision to run American operations from Boston is a well-worn path for high-tech firms, with more than 200 Israeli-founded businesses employing more than 9,000 people in IT and life sciences roles, according to a 2016 study.Guardicore’s Nathan Perdue tells Xconomy the pr...
Tags: Deals, Boston, Massachusetts, Israel, US, Tel Aviv, San Francisco, Trends, Tech, Cybersecurity, East Coast, Partech Ventures, Battery Ventures, Qumra Capital, Deutsche Telekom Capital Partners, National blog main


Merck Preempts Peloton Therapeutics IPO With $1B Acquisition Deal

Merck has reached a deal to acquire Peloton Therapeutics, and its Phase 3-ready kidney cancer drug, for $1.05 billion.Under the agreement announced Tuesday, Merck (NYSE: MRK) will pay the sum in cash up front. If Peloton’s drug candidates reach the market and hit sales targets, shareholders of privately held Pelton could gain up to $1.15 billion in milestone payments.The acquisition agreement comes one day before Dallas-based Peloton was expected to go public. Under IPO terms the company set la...
Tags: Deals, New York, Cancer, Trends, Investing, Merck, Dallas, Biotech, Drug, Life Sciences, Clinical Trials, PELTON, Peloton, National blog main, New York blog main, New York top stories


ACC’s New Fashion Incubator Follows Growth of Industry in Austin

Austin— Though small, Austin’s fashion-technology community is growing. Not only have more businesses started moving to the city, now a new program at Austin Community College is hoping to further drive innovation in the industry.“We are looking to create a full pipeline (of resources) for promising designers,” says Nina Means, director of the newly opened Fashion Incubator at Austin Community College.The program was launched at the end of April and provides both students and local-to-Austin fa...
Tags: Startups, Wearables, New York, Texas, Funding, Trends, Tech, Investment, E-commerce, People, Vc, Austin, Innovation, Venture Capital, M&a, Athleisure


HAP Partners With Livongo on Tech-Enabled Diabetes Compliance Program

As digital health applications continue to grow in popularity, yet achieve only mixed results, one area in which tech-enabled tools have found success is among diabetes patients.Health Alliance Plan (HAP), a Detroit-based nonprofit health insurance provider, wants to leverage that success with a new program in partnership with Mountain View, CA-based Livongo, maker of health tech tools. Called Livongo for Diabetes, the initiative allows HAP Medicare Advantage members with type 1 or type 2 diabe...
Tags: Startups, Entrepreneurship, Trends, Tech, Software, Diabetes, Healthcare, Innovation, Health Insurance, Detroit, Mobile App, Healthtech, Medical Devices, Centers for Disease Control, Medicare Advantage, Amazon Alexa


Hewlett Packard Enterprise Buying Supercomputer Pioneer Cray for $1.3B

Hewlett-Packard Enterprise will pay $1.3 billion to acquire Cray, a Seattle business that develops software used in supercomputers and other high-powered machines.High-performance computing technologies, such as those developed by Cray, are seen as central to sorting through “the explosion of data” resulting from innovations in areas like artificial intelligence and data analytics, HPE says.San Jose, CA-based HPE (NASDAQ: HPE) will pay $35 a share in cash to acquire Cray (NASDAQ: CRAY). That pr...
Tags: Deals, Startups, Big Data, San Francisco, Trends, Tech, Hp, Analytics, It, Computers, Software, M&a, Machine Learning, Ibm, Supercomputers, Data Centers


San Diego Life Sciences Roundup: MedCrypt, LunaDNA, Dynacure & More

Let’s catch up with the latest life sciences news in San Diego.— Cybersecurity company MedCrypt, which makes software to protect medical devices, raised a $5.3 million Series A funding round.The company says it will use the new funds to hire new salespeople and engineers and further develop its technology, which medical devices vendors use to secure data traveling between or stored on devices. It also offers real-time monitoring and alerts about potential security threats.“Patient data privacy ...
Tags: Y Combinator, Funding, Trends, Tech, Vc, San Diego, Biotech, Financing, Bain Capital Ventures, 23andMe, Bill Maris, Eniac Ventures, Life Sciences, ARCH Venture Partners, Ionis Pharmaceuticals, Osage University Partners


PlanetM Awards New Grants to Advance Mobility Pilots in Michigan

PlanetM, the state of Michigan-backed business development organization, has announced a new batch of grants that aim to entice mobility startups and corporations to pilot their innovations in Michigan, or test and validate their technology at one of Michigan’s proving grounds.PlanetM has awarded a total of $440,000 in grants to five companies. The startups are working on pilots such as secure delivery of prescription medications to rural locations, new GPS technology, and autonomous campus shu...
Tags: Startups, Entrepreneurship, Funding, Trends, Tech, Software, Innovation, Michigan, Mobility, Detroit, Continental, Michigan Technological University, DENSO, National blog main, Detroit blog main, Detroit top stories


Boston Tech Watch: Hydrow, Sea Machines, Toast, Pillar & More

[Updated, 9:05 am. See below] Another $100 million for early stage investing in Boston. Check-out machines are becoming clock-in machines. A hundred-plus startups join MassChallenge’s latest cohort in Boston. Read on for more of this week’s Boston tech news.—Rowing machine startup Hydrow added $7 million to the $20 million it raised in its Series A funding round in February. The new capital comes from Green Bay Packers Quarterback Aaron Rodgers’ Rx3 Ventures, The Raptor Group, The Yard Ventures...
Tags: Google, Amazon, Deals, Facebook, Ipo, Boston, Advertising, Trends, Tech, Cybersecurity, Autonomous, Maritime, Venture Capital, Aaron Rodgers, Green Bay Packers, Tripadvisor


Bio Roundup: Generic Drugs Graft, ASCO Ahead, ElevateBio Rises & More

Generic drugs are supposed to give consumers more choices and a counterweight to more costly branded medications. During his tenure as FDA commissioner, Scott Gottlieb often spoke about generics as a market force that could help tame climbing drug prices. But such tools only work when companies play fair.A lawsuit is now claiming that many top generic drug makers routinely conspired to avoid competition. In a more than filed in federal court in Connecticut, 44 states allege that 18 generic dr...
Tags: Deals, Startups, Lawsuit, Breast Cancer, Drugs, Cancer, Trends, Investing, Hypertension, Connecticut, Venture Capital, Private Equity, Fda, National, Biotech, Cystic Fibrosis


Apptio Continues Acquisition Spree With Deal to Buy Cloudability

Apptio, a Bellevue, WA-based company that helps corporate technology leaders manage their IT spending, announced Thursday it has agreed to acquire Cloudability, a Portland, OR-based developer of software for tracking cloud-computing expenditures.Apptio’s news release announcing the deal did not disclose any of its financial terms.The deal, which comes on the heels of other acquisitions Apptio has made in recent years, would create a combined company able to offer customers a “mature and powerfu...
Tags: Google, Amazon, Deals, Microsoft, Trends, Tech, Analytics, It, Software, Portland, Aws, Bp, Seattle, Amazon Web Services, Slack, Alphabet


BioClarity, Maker of “Clean, Green” Skincare Products, Raises $13M

BioClarity, which sells plant-based skincare products to online shoppers, announced Wednesday that it has raised a $13 million investment round.The San Diego-based company is part of Adigica Health, an e-commerce company founded in 2016 to develop and market direct-to-consumer healthcare products.Prolog Ventures led the round with a $6 million investment; BioClarity said earlier investors, which it didn’t name, also participated. Prolog, which has offices in St. Louis, MO, and Newark, NJ, backs...
Tags: Startups, Trends, Startup, Tech, San Diego, Biotech, Life Sciences, Newark NJ, St Louis MO, David Hale, National blog main, New York blog main, San Diego blog main, San Diego top stories, Prolog Ventures, BioClarity


Pillar Fuels Second Go-Round With $100M Fund for Boston Startups

It took a few more years than initially planned, but early-stage venture firm Pillar has raised the $100 million fund it wanted.Launching with fanfare in 2016 under former North Bridge Venture Partners’ Jamie Goldstein, Pillar set its sights on nine digits worth of cash but ended up only raising $57 million. It has since sent that money into early stakes in 26 companies, including Algorand, Desktop Metal, PillPack, Circle, Flipside Crypto, Hometap, Kuebix, PathAI, and Asimov.Today, the firm ann...
Tags: Amazon, Deals, Boston, Trends, Tech, Venture Capital, Carbonite, Tripadvisor, PillPack, North Bridge Venture Partners, Ginkgo Bioworks, Runkeeper, Clearsky Data, Draftkings, Pluralsight, Circle


Whiskey Coffee, Immigration, AI: MassChallenge’s New Austin Cohort

Austin—MassChallenge has picked the 74 early-stage companies that will eventually compete for a portion of $500,000 in cash as a part of its Austin accelerator program. They’re startups that are developing products in a wide range of sectors, including life sciences, agriculture, and artificial intelligence.A majority of the startups are from Texas, although some come from elsewhere in the US and world, including California, Virginia, Mexico, and Israel. Many of the founders are women: 56 perce...
Tags: Startups, Accelerator, Texas, Technology, Magnets, Cloud Computing, Cancer, Israel, Immigration, US, Employment, Trends, Startup, Tech, Diversity, Crops


Whiskey Coffee, Immigration, AI: MassChallenge Austin 2019 Startups

Austin—MassChallenge has picked the 74 early-stage companies that will eventually compete for a portion of $500,000 in cash as a part of its Austin accelerator program. They’re startups that are developing products in a wide range of sectors, including life sciences, agriculture, and artificial intelligence.A majority of the startups are from Texas, although some come from elsewhere in the US and world, including California, Virginia, Mexico, and Israel. Many of the founders are women: 56 perce...
Tags: Startups, Accelerator, Texas, Technology, Magnets, Cloud Computing, Cancer, Israel, Immigration, US, Employment, Trends, Startup, Tech, Diversity, Crops


Karat Gets $28M for Software, Team That Assess Job-Seeking Engineers

Karat, a Seattle-based startup that uses a combination of software and a stable of freelance interviewers to help tech companies assess job applicants, announced Wednesday it has raised $28 million in new funding.Tiger Global Management led the Series B funding round, Karat says. Other participating investors included return backers Norwest Venture Partners and 8VC. Karat says it has raised more than $41 million since launching in 2014.Karat plans to use some of the proceeds from the financing ...
Tags: Deals, Startups, Pinterest, Interviews, Trends, Tech, Recruiting, Paypal, HR, Vc, Human Resources, Seattle, Interviewing, Indeed, Intuit, Hiring


Ginkgo Eyes Antibiotics With Deal for Warp Drive’s Gene “Mining” Tech

Microbes designed by Ginkgo Bioworks are used in consumer products such as fragrances and beverages, and they’re undergoing research for applications in agriculture and medicine. The synthetic biology company has been pushing to expand its technology to more uses, and its latest deal moves the firm further into pharmaceutical research.Boston-based Ginkgo said Wednesday that it has acquired the “genome mining” technology of Warp Drive Bio, which developed technology to find “natural products,” s...
Tags: Deals, Startups, Drugs, Boston, Cancer, Trends, Cannabis, Biotech, Antibiotics, Antibiotic Resistance, Ginkgo Bioworks, Life Sciences, Bayer, Warp Drive, Jason Kelly, REVOLUTION Medicines


Vertex Continues Plan to Diversify, Strikes a $70M Pact With Kymera

Vertex Pharmaceuticals is best known for its cystic fibrosis franchise. But over the past several years Vertex has been making inroads elsewhere, and a deal it is announcing this morning continues that strategy.Vertex (NASDAQ: VRTX), of Boston, will pay privately held startup Kymera Therapeutics $70 million to form an alliance to develop a group of drugs for “serious specialty diseases.” Vertex won’t say which ones, but beyond cystic fibrosis (CF), where it has three FDA-approved drugs that gen...
Tags: Deals, Startups, Boston, Trends, Vc, Fda, GlaxoSmithKline, Biotech, Pain, Cystic Fibrosis, Life Sciences, CRISPR Therapeutics, Vertex, Merck KGaA, Hepatitis C, Vertex Pharmaceuticals



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