Discoverey of four SARS-CoV-2 Mpro inhibitors, boceprevir, calpain inhibitors II and XII and GC-376

A team of scientists from the United States has recently revealed that small molecule inhibitors of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease exhibit potent antiviral activity. These inhibitors show better efficacy when used in combination with antiviral medicine Remdesivir. The study is currently available on the bioRxiv* preprint server.
Tags: Health, United States

Most SARS-CoV-2-infected individuals develop durable B cell-mediated immunity

Researchers from the Johns Hopkins University and The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA, investigated the durability of B cell immunity following SARS-CoV-2 infection and recovery in their recent work published on the preprint server medRxiv.
Tags: Health, Johns Hopkins University

Evidence of robust and persistent antibodies against SARS-CoV-2

A team of researchers from the Icahn School of Medicine at Mount Sinai, New York, have worked in collaboration to try and answer one of the most baffling questions surrounding the coronavirus disease 19 (COVID-19) pandemic: do antibodies against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) last after a primary infection?
Tags: Health, Icahn School of Medicine, Mount Sinai New York

SARS-CoV-2 mutations becoming more contagious

A team of researchers working with Scott Wesley Long from Houston Methodist Hospital and colleagues from Texas, New York, and Illinois studied the patterns of genetic mutations of SARS CoV-2 and its impact on the second wave of infections worldwide.
Tags: Health, Illinois, Houston Methodist Hospital, Texas New York, Scott Wesley Long

BfR-Corona-Monitor: Many respondents have become more cautious about coronavirus

Starting this week, the new regulations for the containment of the coronavirus adopted by the Federal Government and the Länder will come into force throughout Germany.
Tags: Health

Electrical Cable Jammed up 13-Year-Old Boy’s Bladder for 3 Months

Yet another curious youth living in China has done the painfully regretful deed of inserting an object up his urethra, the “choice of obstruction” this time being an electrical cable, which was nestled in the child an entire three months before being extracted by doctors. The victim, a 13-year-old boy known as Xiao He, had […]
Tags: Health, Children, China, Accidents, Medical, International, Bizarre, Anime, Xiao, Penis Abuse

Key populations need to be prioritized for early COVID-19 immunization in Canada

Canada's National Advisory Committee on Immunization (NACI) recommends vaccinating key populations, such as people at risk of severe illness or death, those at risk of transmitting the virus and essential workers, during the initial rollout of a COVID-19 vaccine in Canada.
Tags: Health, Canada

SARS-CoV-2 T-cell immunity is retained for at least six months

Now, a new study published on the preprint server bioRxiv shows that functional SARS-CoV-2-specific T-cell responses are retained for six months following infection. However, the strength of this response depends on the clinical features of the primary infection.
Tags: Health

United States is falling behind in the health care of older population, study shows

An international study led by UCLA Fielding School of Public Health researchers has determined that the United States is far from the most effective healthcare provider for those 50 and older among 23 countries, ranging from Austria to the United States.
Tags: Health, Austria, United States, UCLA Fielding School of Public Health

WHO releases a series of SIDS Health and Climate Change Country Profiles

Small Island Developing States are among the most vulnerable nations to climate change in the world. Yet, many island states are also leading in the global response to climate change, through ambitious emissions reduction targets, adaptation actions, and developing climate resilient health systems.
Tags: Health, Small Island Developing States

Families with a terminally ill patient could benefit from social tourism

Since the latter half of the 20th century, vacationing has grown increasingly synonymous with tourism. This has been attributed to disposable incomes rising for many people, budget commercial airlines taking to the sky, and multitudes of tour facilitators entering the market, among other things.
Tags: Health

New, effective CRISPR-based gene drive approach to control transmission of malaria parasites

Employing a strategy known as "population modification," which involves using a CRISPR-Cas9 gene drive system to introduce genes preventing parasite transmission into mosquito chromosomes, University of California researchers have made a major advance in the use of genetic technologies to control the transmission of malaria parasites.
Tags: Health, University Of California

SARS-CoV-2 attack rates among household contacts higher than among non-household contacts

Now, a team of researchers at the National Centre for Infectious Diseases in Singapore aimed to determine the transmission risk factors of SARS-CoV-2 among household and non-household contacts.
Tags: Health, Singapore, National Centre for Infectious Diseases

Johns Hopkins researchers design tiny, star-shaped microdevices to deliver drugs

Inspired by a parasitic worm that digs its sharp teeth into its host's intestines, Johns Hopkins researchers have designed tiny, star-shaped microdevices that can latch onto intestinal mucosa and release drugs into the body.
Tags: Health, Johns Hopkins

Rubbery bioelectronic cardiac patch can monitor and treat heart disease

Pacemakers and other implantable cardiac devices used to monitor and treat arrhythmias and other heart problems have generally had one of two drawbacks - they are made with rigid materials that can't move to accommodate a beating heart, or they are made from soft materials that can collect only a limited amount of information.
Tags: Health

Study finds a subset of quick COVID-19 healers and antibody 'sustainers'

One of the pressing questions about COVID-19 remains: How long does immunity last? One key indicator of immunity is the presence of virus-specific antibodies.
Tags: Health

COVID-19 amplifies health disparities [PODCAST]

“The daily email update on COVID-19 affecting our hospital system is a glaring reflection of the health disparities amongst those in marginalized groups. The farther south you go, generally in San Diego, the higher the number of socioeconomically disadvantaged persons, and that tends to include a disproportionate number of persons of color.  These populations may […] Find jobs at Careers by Search thousands of physician, PA, NP, and CRNA jobs now. Learn more.
Tags: Health, Podcast, San Diego, PA NP, Public Health & Policy, CRNA

AI speech processing framework detects inaudible COVID-19 cough

Now, a team of researchers at the Massachusetts Institute of Technology (MIT) has found that asymptomatic people may differ from those who are healthy in the way they cough. The differences are inaudible to the human ear but can be detected by artificial intelligence (AI).
Tags: Health, Massachusetts Institute of Technology MIT

Study shows active surveillance to be safe for African American men with low-risk prostate cancer

Previous studies have shown that African American men are 2.4 times as likely to die from prostate cancer compared to non-Hispanic white men.
Tags: Health

NSW-Victoria border to open on 23 November; Australia awaits American election outcome – politics live

‘We need to keep moving forward as we live with Covid-19,’ Gladys Berejiklian says. We’ll also be bringing you Australian reaction to that election, as it happens Follow our US election live blogFollow the live results trackerGuide: what time results are expected – and what to watch for 12.15am GMT Queensland has recorded two new Covid cases - both people are in hotel quarantine. 12.11am GMT NSW has also recorded three locally transmitted cases – but all were linked to known clusters and...
Tags: Health, Australia, US, Australia news, Australian politics, Queensland, New South Wales, Sydney, Victoria, Scott Morrison, Anthony Albanese, Gladys Berejiklian, Coronavirus, COVID

16 new lineages of SARS-CoV-2 emerge in South Africa despite lockdown

Published in a recent medRxiv* paper, researchers from South Africa, the United Kingdom, and Brazil found that these mutations in SARS-CoV-2 lineages are localized to South Africa. These unique strains, not found elsewhere in the world, are thought to have contributed around 42% to the country's total infection rate.
Tags: Health, South Africa, United Kingdom, Brazil

UB study reveals the nutritional properties of oil from wild olive trees

The oil from wild olive trees has excellent sensorial, physicochemical and stability characteristics from a nutritional point of view, according to an article published in the journal Antioxidants.
Tags: Health, UB

Researchers to explore the role of gut microbes in childhood celiac disease

Boston College Assistant Professor of Biology Emrah Altindis has received a three-year, $300,000-grant from the G. Harold and Leila Y. Mathers Foundation for research into childhood celiac disease.
Tags: Health, Boston College, Emrah Altindis, G Harold and Leila Y Mathers Foundation

Adaptive evolution of human coronaviruses may necessitate frequent reformulation of vaccines

Researchers from the Vaccine and Infectious Disease Division at the Fred Hutchinson Cancer Research Center, USA, have revealed that adaptive evolution in the antigenic regions facilitates seasonal coronaviruses to escape the host immune responses and to cause recurrent infections.
Tags: Health, Fred Hutchinson Cancer Research Center USA

Some of the main osteoporosis treatments could have a protective effect against COVID-19

Some of the principal treatments for osteoporosis, denosumab, zoledronate and calcium, could have a protective effect against COVID-19 in patients who take them, specifically a 30 to 40% reduction in the rate of infection, according to the results of a joint study by Hospital del Mar, the Hospital del Mar Medical Research Institute (IMIM), Pompeu Fabra University and the Pere Virgili Health Park.
Tags: Health

Study identifies structural, functional brain differences in people with occupational blast exposure

Military and law enforcement personnel with extensive occupational blast exposure had statistically significant differences in brain imaging measures compared to nonexposed control personnel.
Tags: Health

Rapid generation of divergent synthetic antibodies against SARS-CoV-2 in a cell-free engineering platform

In a groundbreaking bioRxiv paper, a research group from the Massachusetts Institute of Technology (MIT), Harvard University and Howard Hughes Medical Institute in the US engineered antibodies against the receptor-binding domain (RBD) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein by using a novel approach. In doing so, they also identified more than 800 predicted binder families.
Tags: Health, US, Howard Hughes Medical Institute

UConn researcher identifies genes and regulatory elements critical to heart development

The advent of genome science has given researchers an unprecedented ability to understand the root causes of a host of conditions.
Tags: Health, UConn

L.A. County reports another 1,224 coronavirus cases, 23 more deaths

Los Angeles County reported 1,224 new cases of COVID-19 and 23 additional deaths on Tuesday, Nov. 3, bringing the county’s totals to 311,745 cases and 7,097 fatalities. The numbers come as public health officials continued to warn that the area’s coronavirus crisis is worsening and threatens to become even more dire during the upcoming holiday season unless behaviors rapidly change. “With our cases increasing, we are concerned about holiday gatherings and cooler weather where people are more lik...
Tags: Health, Business, News, Education, California, Sport, Soccer, Long Beach, Disneyland, Pasadena, Usc, Los Angeles County, Ferrer, Barbara Ferrer, Los Angeles County Health Department, Top Stories LADN

Integrity commission under fire; Australia awaits US election outcome – politics live

Senate crossbenchers criticise government’s draft Commonwealth Integrity Commission, calling it a ‘sham Icac’. We’ll also be bringing you Australian reaction to that election, as it happens Follow our US election live blogFollow the live results trackerGuide: what time results are expected – and what to watch for 11.18pm GMT That first CPAC panel ended with some pretty calm and chill rhetoric. Cameron talks for a while about how the “the mainstream media, the bureaucracy, the academia, the N...
Tags: Health, Australia, Senate, US, Australia news, Australian politics, Queensland, Cameron, New South Wales, Victoria, Liberal party, Scott Morrison, Anthony Albanese, Commonwealth Bank, RBA, CPAC

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