Study highlights previously unknown mechanisms involved in myeloma resistance

A group of researchers led by Maximillian Merz, MD, Assistant Professor of Oncology with the Myeloma team at Roswell Park Comprehensive Cancer Center, conducted the first prospective clinical trial investigating spatial heterogeneity in patients with either relapsed/refractory or newly diagnosed multiple myeloma.
Tags: Health, Roswell Park Comprehensive Cancer Center, Maximillian Merz

Researchers evaluate safety of novel therapy for patients with non-Hodgkin lymphoma

Roswell Park Comprehensive Cancer Center's Francisco J. Hernandez-Ilizaliturri, MD, along with a team of researchers from other institutions, has been investigating a novel therapy for patients with relapsed or refractory B-cell non-Hodgkin lymphoma.
Tags: Health, Hodgkin, Roswell Park, Francisco J Hernandez Ilizaliturri

New article highlights health disparities, social determinants of health

The December issue of The American Journal of Gastroenterology is now available and features new clinical research across a wide range of gastroenterology and hepatology topics, including health disparities, colorectal cancer, cirrhosis, pediatric gastroenterology, the environmental impact of endoscopy, and more.
Tags: Health

Study finds no significant change in preterm or stillbirth rates during COVID-19 pandemic

Despite early reports suggesting a decline in preterm births during the COVID-19 pandemic period, an analysis by researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania has found no change in preterm births or stillbirths at two Philadelphia hospitals in the first four months of the pandemic.
Tags: Health, Philadelphia, University of Pennsylvania, Perelman School of Medicine, Children s Hospital

Antibody responses to SARS-CoV-2 virus disappear quickly during convalescence, indicates study

A new 5-month longitudinal analysis of 254 COVID-19 patients who displayed a wide range of disease severity - from asymptomatic to deadly illness - suggests that IgA and IgM antibodies to the SARS-CoV-2 virus disappear quickly during convalescence.
Tags: Health

Honey bees use visual signal to deter predators

An Asian hornet sets its sights on a busy honey bee hive. If all goes according to plan, the hornet's attack will result in a haul of bee larvae, precious nourishment to pilfer and feed to its own hornet young.
Tags: Health

Patients with atopic dermatitis more likely to have autoimmune diseases

In a recent study published in the British Journal of Dermatology, individuals with atopic dermatitis, or eczema, were more likely to also have various autoimmune diseases, especially those involving the skin, the gastrointestinal tract, or the connective tissue.
Tags: Health, British Journal of Dermatology

Study: Caplacizumab not cost effective for treating thrombotic thrombocytopenic purpura

In a new study by Yale Cancer Center researchers, the drug caplacizumab is shown not to be cost-effective in treating thrombotic thrombocytopenic purpura (TTP) when added to the standard-of-care.
Tags: Health, Yale Cancer Center

Researchers analyze outcomes in patients with primary central nervous system lymphoma

Primary central nervous system lymphoma (PCNSL) is a type of cancer that develops in the brain and or spinal cord.
Tags: Health

Research team develops a new decoding method for viral genes

Comprehensive identification of viral proteins encoded by viral genes is required to understand the pathophysiology of viral infections.
Tags: Health

Researchers develop new approach for COVID-19 testing

Researchers from UC San Francisco and the Chan Zuckerberg Biohub have developed a new approach for COVID-19 testing that detects a distinct pattern of immune gene expression in infected individuals.
Tags: Health, UC San Francisco, Chan Zuckerberg Biohub

Drug prescribed for rare enzyme deficiency shows promise to treat herpes viruses

A drug currently prescribed to treat a rare enzyme deficiency can help cells clear the herpes simplex 1 and herpes simplex 2 viruses, according to a new study published in the journal Science Advances.
Tags: Health

Adolescent competitive sport participation linked to better fitness at midlife in women

Females who participate in competitive sport during adolescence have better fitness at midlife than do females with no competitive sport background in adolescence, reveals a study conducted at the University of Jyväskylä.
Tags: Health

Single-cell sequencing provides new fundamental insights into 'abdominal brain'

Researchers at Karolinska Institutet have succeeded in mapping the neuron types comprising the enteric nervous system in the intestine of mice.
Tags: Health, Karolinska Institutet

Chemotherapy combined with blinatumomab increases survival for patients with Ph-negative B-ALL

A study led by The University of Texas MD Anderson Cancer Center showed that first-line treatment with a regimen of chemotherapy combined with the monoclonal antibody blinatumomab resulted in increased survival and achieved a high rate of measurable residual disease (MRD) negativity for patients who were newly diagnosed with a high-risk form of acute lymphoblastic leukemia (ALL) known as Philadelphia chromosome-negative B-cell ALL (Ph-negative B-ALL).
Tags: Health, Philadelphia, University of Texas MD Anderson Cancer Center

Study finds CAR T cell therapy as effective as first-line treatment for high-risk large B-cell lymphoma

A study led by researchers at The University of Texas MD Anderson Cancer Center found that axi-cel, an autologous anti-CD19 chimeric antigen receptor (CAR) T cell therapy, is a safe and effective first-line therapy for patients with high-risk large B-cell lymphoma (LBCL), a group with an urgent need for new and effective treatments.
Tags: Health, The University of Texas MD Anderson Cancer Center

RNA mutations within common bacterium linked to invasive meningococcal disease

Researchers at Karolinska Institutet in Sweden have come one step closer toward understanding why some people become seriously ill or die from a common bacterium that leaves most people unharmed.
Tags: Health, Sweden, Karolinska Institutet

L.A. County’s COVID-19 hospitalizations surpass 3,000, state reports

Los Angeles County hit another milestone, with the number of COVID-19 patients currently hospitalized surpassing 3,000 for the first time, the state reported Monday, Dec. 7, the same day  the county’s health department reported that the number of health care workers testing positive for the coronavirus has more than doubled in one week’s time. Although state data show 3,113 patients hospitalized in L.A. County, the county reported a slightly lower — though similarly alarming — figure of 2,988 pa...
Tags: Health, Business, News, Education, Government, Sport, Public Health, Soccer, Long Beach, Community, Lausd, Pasadena, Local News, Southern California, Los Angeles County, Ferrer

COVID-19 crisis increases burden of dementia caregivers

Caregivers of people with dementia and milder forms of neurocognitive disorder bear a heavy burden.
Tags: Health

West Health Policy Center forms CIDSA to provide independent analysis of drug pricing policies

The West Health Policy Center, a nonprofit and nonpartisan policy research and education organization, announced today the formation of the Council for Informed Drug Spending Analysis, a group made up entirely of leading policy experts from the worlds of academia and healthcare.
Tags: Health, West Health Policy Center, CIDSA, Council for Informed Drug Spending Analysis

Researchers develop potential non-drug, non-surgical, long-acting therapy for glaucoma

Researchers have developed a potential new treatment for the eye disease glaucoma that could replace daily eye drops and surgery with a twice-a-year injection to control the buildup of pressure in the eye.
Tags: Health

COVID-19 stay-at-home orders linked to increased alcohol consumption

Binge drinkers increased their alcohol consumption by nearly 20% during COVID-19 stay-at-home orders, according to new research by public health experts at The University of Texas Health Science Center at Houston.
Tags: Health, University of Texas Health Science Center

New spin-out company to bring the world's most advanced brain scanner to market

A new type of wearable brain scanner, designed to allow people to move freely whilst being scanned, is a step closer to being used in hospitals with the launch of a new partnership.
Tags: Health

Testing for tumor DNA can help predict risk of relapse after transplant in DLBCL patients

Many patients with diffuse large B-cell lymphoma (DLBCL) can be cured by a transplant using their own blood-forming stem cells, but as many as half eventually relapse.
Tags: Health

Kessler Foundation receives COVID-19 crisis funding to support spinal cord injury community

Kessler Foundation received a $10,000 grant from the Craig H. Neilsen Foundation's crisis funding to support the spinal cord injury (SCI) community and critical research amid the COVID-19 pandemic.
Tags: Health, SCI, Kessler Foundation, Craig H Neilsen Foundation

Henry Ford and United Outstanding Physicians join hands to enhance cancer care

Henry Ford Cancer Institute and United Outstanding Physicians, a physician organization comprising nearly 1,000 independent private practice physicians across Southeast Michigan, have come together to enhance cancer care and make navigating the cancer journey easier for their patients.
Tags: Health, Henry Ford, Southeast Michigan, United Outstanding Physicians

UIC researchers use new approach to identify genes that cause diabetic retinopathy

In a search to discover the genetic factors underlying diabetic retinopathy, University of Illinois Chicago researchers also have identified a new approach that can be used as a template to study other diseases.
Tags: Health, UIC, University of Illinois Chicago

BGU researchers uncover potential bittersweet effects of natural sweetener stevia

According to a new study by Ben-Gurion University of the Negev researchers, the natural sweetener stevia may lead to a gut microbial imbalance.
Tags: Health, Ben Gurion University of the Negev

Simple warning labels reduce sugary drink consumption among college students

As municipalities have taxed sugar-sweetened beverages and schools and worksites have banned their sales, university researchers have found that simple warning labels on such beverages in a college cafeteria helped students reduce their reported consumption of drinks by 14.5 percent.
Tags: Health

Research uncovers novel anti-craving mechanism to treat cocaine relapse

Cocaine continues to be one of the most commonly abused illicit drugs in the United States. Pre-clinical literature suggests that targeting glucagon-like peptide-1 receptors (GLP-1Rs) in the brain may represent a novel approach to treating cocaine use disorder.
Tags: Health, United States

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