Health


 

Antibody-Fc-mediated innate immunity shapes COVID-19 severity

A short paper that appeared recently on the preprint bioRxiv server pointed to a link between specific characteristics of anti-SARS-CoV-2 antibodies associated with the severity of COVID-19.
Tags: Health


Intranasal vaccination effectively reduces viral shedding of SARS-CoV-2 in monkeys

A new preprint that appeared on the bioRxiv server reports that intranasal vaccination with the D614G variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in rhesus monkeys reduces viral shedding. This is an experiment in non-human primates (NHP), and its extrapolation to humans is unclear as yet.
Tags: Health, NHP


Structure of SARS-CoV-2 cytoplasmic tail uncovered

The virus's cytosolic tail also interacts with the host cell to promote its entry into the endoplasmic reticulum (ER). A new study appearing on the bioRxiv preprint server elucidates the conformation of this region of the virus, which will help understand how its form is related to its function in viral entry.
Tags: Health


Effect of mutations in the South African SARS-CoV-2 variant on transmission and neutralization

One such strain is the South African 501.V2 and UK B1.1.7 strains, which have been isolated from many countries and seem to spread faster than the ancestral strain. A preprint that recently appeared on the bioRxiv server reports the computational structure of this strain and the possible effect of the mutations on infectivity and neutralization.
Tags: Health, UK


Photos: UCLA School of Dentistry gives out dental hygiene kits during food giveaway

The line of masked people stretched from Tyrone Avenue on to Victory Boulevard for the weekly Central Lutheran Church Mobile Pantry LA Food Bank Food Distribution in Van Nuys on Monday, Jan. 11. During this edition of the food giveaway, those in line would also receive information on dental hygiene and dental kits from the UCLA Dental School. “Dental care is under accessed, especially by underserved communities, and we want them to know there are benefits and access for them,” said Dental Hygien...
Tags: Health, News, Education, Sport, Soccer, Community, Local News, Dental, 288, LA County, Victory Boulevard, Van Nuys, Los Angeles Daily News, UCLA School of Dentistry, Central Lutheran Church, Brummel


Australia's chief medical officer defends AstraZeneca's Covid vaccine amid efficacy concerns

Australia has secured 54m doses of the vaccine some experts say is inferior to Pfizer’s mRNA vaccine, which Australia has bought just 10m doses ofCovid hotspots Victoria; NSW hotspots; Queensland hotspotsNSW and Sydney trend map: where cases are rising or fallingFollow the Australia coronavirus live blogAustralia’s chief medical officer, Prof Paul Kelly, and infectious diseases experts have defended securing 54m doses of a Covid-19 vaccine made by Oxford University and the pharmaceutical company...
Tags: Health, Australia, Australia news, Infectious Diseases, Queensland, Sydney, Astrazeneca, Pharmaceuticals industry, Vaccines and immunisation, Victoria, Pfizer, Oxford University, Paul Kelly, Stephen Turner, Coronavirus, New Zealand Society for Immunology Prof


Bleeding disorder linked to poor clinical outcomes in COVID-19 patients

The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is the pathogen responsible for the ongoing coronavirus disease 2019 (COVID-19) pandemic. Approximately 20-55% of hospitalized COVID-19 patients are reported to have deranged hemostatic laboratory parameters, which suggests coagulopathy.
Tags: Health


Daily circadian cycles may impact our ability to fight disease

An analysis of an exhaustive dataset on cells essential to the mammalian immune system shows that our ability to fight disease may rely more heavily on daily circadian cycles than previously assumed.
Tags: Health


Researchers discover a new approach to inhibit intrahepatic cholangiocarcinoma

Reprogramming the rich connective tissue microenvironment of a liver cancer known as intrahepatic cholangiocarcinoma (ICC) inhibits its progression and resistance to standard chemotherapy in animal models, researchers from Massachusetts General Hospital have found.
Tags: Health, Massachusetts General Hospital


Mothers with multiple children report worse sleep patterns

Mothers with multiple children report more fragmented sleep than mothers of a single child, but the number of children in a family doesn't seem to affect the quality of sleep for fathers, according to a study from McGill University.
Tags: Health


Antigenic "supersite" could improve design of COVID-19 vaccines

Researchers in the United States have defined an antigenic “supersite” within the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that could have important implications for the design of vaccines to protect against coronavirus disease 2019 (COVID-19).
Tags: Health, United States


Study reveals rising risk of mental health problems among COVID-19 health care professionals

The daily toll of COVID-19, as measured by new cases and the growing number of deaths, overlooks a shadowy set of casualties: the rising risk of mental health problems among health care professionals working on the frontlines of the pandemic.
Tags: Health


Scientists determine Ideal Dose Of Stem Cells To control HIV

Scientists have determined the optimal conditions following a stem cell transplant that could control HIV without the need of an everyday pill, according to a study published today in eLife.
Tags: Health


LA city employees agree to delay pay raises – to stave off layoffs and furloughs

Los Angeles city officials and unions representing more than 18,000 city employees have struck a deal on Tuesday, Jan. 12, that would delay pay increases scheduled this year, to avoid layoffs and furloughs for the next five months. The city faces a $675 million shortfall, amid a recession brought on by closures to prevent the spread of the novel coronavirus. In response, city leaders weighed deep cuts, including hundreds of layoffs. Tuesday’s agreement calls for postponing a pair of 2% raises sc...
Tags: Health, Business, Budget, News, La, Government, Los Angeles, Sport, Soccer, Community, SEIU, Southern California, 288, Los Angeles Police Department, LA County, UCLA School of Dentistry


L.A city employees agree to delay pay raises – to stave off layoffs and furloughs

Los Angeles city officials and unions representing more than 18,000 city employees have struck a deal on Tuesday, Jan. 12, that would delay a pay increases scheduled this year, to avoid layoffs and furloughs for the next five months. The city faces a $675 million shortfall, amid a recession brought on by closures to prevent the spread of the novel coronavirus. In response, city leaders weighed deep cuts, including hundreds of layoffs. Tuesday’s agreement calls for postponing a pair of 2% raises ...
Tags: Health, Business, Budget, News, California, Government, Los Angeles, Sport, Soccer, Community, Lausd, SEIU, Los Angeles Police Department, LA County, Top Stories LADN, Top Stories Breeze


Study investigates the metabolites involved in the growth and spread of melanoma

The first step in treating cancer is understanding how it starts, grows and spreads throughout the body. A relatively new cancer research approach is the study of metabolites, the products of different steps in cancer cell metabolism, and how those substances interact.
Tags: Health


Robotic device powered by patients’ own brains helps improve stroke rehabilitation

Stroke survivors who had ceased to benefit from conventional rehabilitation gained clinically significant arm movement and control by using an external robotic device powered by the patients' own brains.
Tags: Health


Stimulation method helps some people with spinal cord injury to regain hand and arm mobility

Almost 18,000 Americans experience traumatic spinal cord injuries every year. Many of these people are unable to use their hands and arms and can't do everyday tasks such as eating, grooming or drinking water without help.
Tags: Health


Hypoxia signaling pathway could lead to COVID-19 treatments

Researchers in Spain have demonstrated that studying the hypoxia signaling pathway could provide opportunities for treating coronavirus disease 2019 (COVID-19).
Tags: Health, Spain


Inherited or transmitted gut microbes affect skeletal development in animals

Gut microbes passed from female mice to their offspring, or shared between mice that live together, may influence the animals' bone mass, says a new study published today in eLife.
Tags: Health


Researchers call for stronger regulations to reduce health burden of smokeless tobacco

Researchers at the University of York are calling for more stringent regulatory measures to reduce the health burden of smokeless tobacco, a product often found in UK stores without the proper health warnings and as a result of illicit trading.
Tags: Health, UK, University of York


K-State medical director contributes to research on SARS-CoV-2 transmission and quarantine periods

Kyle Goerl, the medical director of Kansas State University's Lafene Health Center, is part of a collaborative team that is providing research-based guidance during the COVID-19 pandemic.
Tags: Health, K State, Kyle Goerl, Kansas State University s Lafene Health Center


New technique may enable researchers to more efficiently isolate and identify rare T cells

Scientists from the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have developed a technique that will enable researchers to more efficiently isolate and identify rare T cells that are capable of targeting viruses, cancer and other diseases.
Tags: Health, Ucla, Eli


Incidence of osteoporotic hip fractures expected to escalate in some Eurasian countries

A detailed analysis of the burden of osteoporosis in eight Eurasian countries has found that osteoporosis is a significant and growing health problem in the region that will escalate in the future due to expected demographic changes.
Tags: Health


Leading pediatric hospital reveals top AI models in COVID-19 Grand Challenge

The top 10 results have been unveiled in the first-of-its-kind COVID-19 Lung CT Lesion Segmentation Grand Challenge, a groundbreaking research competition focused on developing artificial intelligence (AI) models to help in the visualization and measurement of COVID specific lesions in the lungs of infected patients, potentially facilitating to more timely and patient-specific medical interventions.
Tags: Health


Poor gut health may adversely affect COVID-19 prognosis

People infected with COVID-19 experience a wide range of symptoms and severities, the most commonly reported including high fevers and respiratory problems.
Tags: Health


Study examines the role of gut microbes in anorexia

You are likely familiar with the serious consequences of anorexia for those who experience it, but you might not be aware that the disorder may not be purely psychological.
Tags: Health


Highly sensitive wearable sensor shows promise for cardiorespiratory monitoring

A highly sensitive wearable sensor for cardiorespiratory monitoring could potentially be worn continuously by cardiac patients or others who require constant monitoring.
Tags: Health


Metabolites may be predictive indicators of patients at risk for recurrent major depression

Researchers at University of California San Diego School of Medicine, in collaboration with Dutch scientists, have found that certain metabolites -; small molecules produced by the process of metabolism -; may be predictive indicators for persons at risk for recurrent major depressive disorder.
Tags: Health


Study: Sugar substitute doesn't lead to the development of diabetes in healthy adults

For those trying to live a healthy lifestyle, the choice between sugar and artificial sweeteners such as saccharin can be confusing.
Tags: Health



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