Single BNT162b2 mRNA dose induces humoral and T cell responses against mutated variants with a history of COVID-19

In a paper recently uploaded to the preprint server bioRxiv by Tauzin et al. (March 18th, 2021) the ability of a single dose of mRNA vaccine to induce humoral and T cell responses against mutated variants are demonstrated and found to be reinforced in individuals with a history of COVID-19.
Tags: Health, Tauzin

Simple SARS-CoV-2 mutations allow escape from the majority of polyclonal antibodies

The group identified a single class of antibodies that target a particular epitope on the RBD of SARS-CoV-2, suggesting that the human polyclonal response to SARS-CoV-2 infection is dominated by a worryingly narrow range of antibodies that target an epitope undergoing rapid mutation.
Tags: Health

Star-shaped brain cells impact the length and depth of sleep in mice

For something we spend one-third of our lives doing, we still understand remarkably little about how sleep works -- for example, why can some people sleep deeply through any disturbance, while others regularly toss and turn for hours each night? And why do we all seem to need a different amount of sleep to feel rested?
Tags: Health

Survey of smokers and vapers in the U.S. during COVID

Researchers at the Massachusetts General Hospital aimed to understand the changes in cigarette and e-cigarette use behaviors among adults in the United States. They found that a third of cigarette smokers and a quarter of vape or e-cigarette users increased their use during the pandemic, mainly due to stress.
Tags: Health, United States, Massachusetts General Hospital

Non-invasive scTS improves handgrip strength, motor control in people with complete tetraplegia

Kessler Foundation researchers demonstrated that spinal cord transcutaneous stimulation (scTS) combined with hand training improves upper extremity and hand function in individuals with motor and sensory compete spinal cord injury (SCI).
Tags: Health, Kessler Foundation

Study identifies metabolic processes associated with multiple, unrelated diseases

Many older, but also increasingly younger, people suffer from several diseases at the same time. Scientists at the Berlin Institute of Health at Charité – Universitätsmedizin Berlin, together with colleagues from Munich and the United Kingdom, have now identified common risk factors that predispose to multiple even seemingly unrelated diseases.
Tags: Health, Munich, United Kingdom, Charité, Universitätsmedizin Berlin, Berlin Institute of Health

B.1.1.7 SARS-CoV-2 variant significantly more dangerous

Now, researchers at the University of Exeter, the NHS Foundation Trust, report a significant increase in mortality risk due to the B.1.1.7 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant.
Tags: Health, University of Exeter the NHS Foundation Trust

Most cancer patients with COVID-19 produce antibodies at a rate comparable to general population

Most people with cancer who are infected by the novel coronavirus produce antibodies at a rate comparable to the rest of the population--but their ability to do so depends on their type of cancer and the treatments they've received, according to a new study by researchers at Montefiore Health System and Albert Einstein College of Medicine.
Tags: Health, Montefiore Health System

New research could help predict acute reactions to psychedelic drugs

As psychedelics gain ground as a potential therapy for mental health disorders, there remains a pressing concern that patients in clinical trials may have adverse effects to the drugs.
Tags: Health

Virginia Tech neuroscientist uses NIH grant to understand astrocytic processes in the healthy brain

Of all the worlds still to be explored, among the most mysterious may be closest to home. Indeed, it may be right between your ears.
Tags: Health, Nih, Virginia Tech

New method could drive down the production cost of antibodies

Antibody injections are a highly desirable treatment for people with chronic diseases such as cancer, psoriasis, Crohn's disease and arthritis. And recently, antibodies have been in the news as a promising treatment for severe cases of COVID-19.
Tags: Health, Crohn

SARS-CoV-2 infection is circadian

An international team of researchers has found that angiotensin-converting enzyme 2 (ACE2) levels in lung cells vary over the day, affecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The virus entry and replication in the lung cells also have a rhythmic cycle, suggesting circadian processes can affect the virus's life cycle.
Tags: Health

New treatment for late-stage neuroendocrine tumors found to be more effective and less toxic

A new treatment for late-stage neuroendocrine tumors (NETs) has been found to be more effective and have fewer side effects than the current standard of care, according to research published in the March issue of The Journal of Nuclear Medicine.
Tags: Health

Disease-driving B cells play a role in the development of NAFLD

New research from the University of Minnesota Medical School suggests that disease-driving B cells, a white blood cell, play a role in the development of non-alcoholic fatty liver disease (NAFLD) - the most common chronic liver condition in the U.S.
Tags: Health, NAFLD, University of Minnesota Medical School

YAP inhibitors could facilitate targeted treatment of basal-like breast cancer

Targeted treatment of basal-like breast cancer could be facilitated by YAP inhibitors in the future. As reported by an MDC team headed by Walter Birchmeier in the scientific journal Cancer Research, this type of cancer requires the support of the YAP protein to stimulate the growth of cancer stem cells.
Tags: Health, Cancer Research, MDC, Walter Birchmeier

Crisis standard of care guidelines may not exacerbate racial inequities

There are two simultaneously occurring pandemics in the U.S.: Racism and COVID-19. "These mutualistic pandemics have thrown into stark focus the separate and unequal systems through which people access health care," explained corresponding author Emily Cleveland Manchanda, MD, assistant professor of emergency medicine at Boston University School of Medicine.
Tags: Health, Emily Cleveland Manchanda

Review: Using biomaterials in dental implants

Announcing a new article publication for BIO Integration journal. In this review article the authors Oliver K. Semisch-Dieter, Andy H. Choi and Martin P. Stewart from the University of Technology Sydney, Ultimo, NSW, Australia discuss the use of biomaterials in dental implants.
Tags: Health, BIO Integration journal In, Oliver K Semisch Dieter Andy H Choi, Martin P Stewart

RedHill provides opaganib treatment under compassionate use exemption for Swiss COVID-19 patients

RedHill Biopharma Ltd., a specialty biopharmaceutical company, today announced that it has acted on a request to provide opaganib treatment on an outpatient basis under compassionate use exemption for several Swiss patients suffering from COVID-19 pneumonia.
Tags: Health, Redhill, RedHill Biopharma Ltd

COVID-19 lockdown restrictions reduced light activity related to socializing and work

A study which looked at activity levels before and during the COVID-19 pandemic has found lockdown restrictions significantly reduced light activity associated with socializing and work.
Tags: Health

10% of older adults have got a new pet during the pandemic, poll shows

A lot of the attention around "pandemic pets" has focused on families with children getting a cat, dog or other pet in 2020, during a time when many people were learning or working from home.
Tags: Health

Study examines workplace mentoring and socializing behaviors in the wake of #MeToo

It's well known that mentoring opportunities are critical for development and career advancement, and are associated with greater job satisfaction and increased earnings and promotions.
Tags: Health

Sealing fistulas more effectively with water-immiscible mussel protein-based bioadhesive

A Korean research team has recently developed an innovative vesico-vaginal fistula treatment method using the mussel adhesive protein (MAP) that can effectively seal fistulas in organs even when exposed to urine.
Tags: Health

UK faces 'Covid decade' due to damage done by pandemic, says report

British Academy review calls for wide-ranging new policies to reverse rise in deprivation and ill healthBritain faces a “Covid decade” of social and cultural upheaval marked by growing inequality and deepening economic deprivation, a landmark review has concluded.Major changes to the way society is run in the wake of the pandemic are needed to mitigate the impact of the “long shadow” cast by the virus, including declining public trust and an explosion in mental illness, the British Academy repor...
Tags: Health, Politics, UK, Society, UK News, Public finance, Poverty, Mental Health, Social exclusion, Inequality, Patrick Vallance, British Academy, Coronavirus

Direct differentiation of progenitor stem-like cells into mesenchymal stem, and osteogenic cells

Epithelial cell rests of Malassez derived from the periodontal ligament were transformed into progenitor stem-like cells by stimulation with epigenetic agents.
Tags: Health

Anti-androgen drugs may help disarm coronavirus spike protein, stop progression of COVID-19

Hormone drugs that reduce androgen levels may help disarm the coronavirus spike protein used to infect cells and stop the progression of severe COVID-19 disease, suggests a new preclinical study from researchers in the Abramson Cancer Center at the University of Pennsylvania and published online in Cell Press's iScience.
Tags: Health, University of Pennsylvania, Abramson Cancer Center

Covid-19 pandemic has a substantial impact on the mental health of young adults

The Covid-19 pandemic severely impacted the mental health of young people, with increased levels of clinical depression being identified, a new study published in the journal Psychiatry Research reports. A decrease in alcohol consumption was also identified amongst young people during the pandemic.
Tags: Health, Psychiatry Research

Computational analysis helps identify hematological malignancies that elude the human eye

Myelodysplastic syndrome (MDS) is a disease of the stem cells in the bone marrow, which disturbs the maturing and differentiation of blood cells. Annually, some 200 Finns are diagnosed with MDS, which can develop into acute leukemia. Globally, the incidence of MDS is 4 cases per 100,000 person years.
Tags: Health, MDS

FDA warns two companies for illegal marketing of unapproved CBD products

The U.S. Food and Drug Administration has issued warning letters to two companies for selling products labeled as containing cannabidiol (CBD) in ways that violate the Federal Food, Drug, and Cosmetic Act (FD&C Act).
Tags: Health, Fda, U S Food and Drug Administration

LA County agrees to partner with Blue Shield on vaccination network

After weeks of concern over potentially losing the huge network of vaccination sites it had built, Los Angeles County has formally agreed to collaborate with healthcare giant Blue Shield, which will provide performance metrics to assess the success of the rollout. The agreement allows the county to continue to coordinate vaccinations via its nearly 400 vaccine providers throughout the region, including in such hard-hit area as South and East L.A. and pockets of the San Fernando Valley. ...
Tags: Health, Business, News, Education, California, Cdc, Government, Sport, Public Health, Soccer, Community, Lausd, Blue Shield, Pasadena, State, Los Angeles County

Study reveals the incidence of structural abnormalities in the developing brain

A large study of brain MRI scans from 11,679 nine- and ten-year-old children reviewed by UC San Francisco neuroradiologists identified potentially life-threatening conditions in 1 in 500 children, and more minor but possibly clinically significant brain abnormalities in 1 out of 25 children.
Tags: Health, UC San Francisco

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