Moffitt researchers use mathematical modeling to help explain outcomes of CAR T-cell therapy

Chimeric antigen receptor T-cell therapy, or CAR T, is a relatively new type of therapy approved to treat several types of aggressive B cell leukemias and lymphomas.
Tags: Health, Moffitt

Researchers reveal a mechanistic link in kidney cancer between fat metabolism and obesity

Altered cellular energetics, a hallmark of cancers, has been associated with obesity. However, links between systemic energy regulation and aberrant cancer cell metabolism have been lacking.
Tags: Health

UArizona researcher finds a unique approach to tackle both Alzheimer’s disease and diabetes

A University of Arizona Health Sciences researcher examined the role of cholesterol in both Alzheimer's disease and Type 2 diabetes to identify a small molecule that may help regulate cholesterol levels in the brain, making it a potential new therapeutic target for Alzheimer's disease.
Tags: Health, University of Arizona Health Sciences

Blood type-incompatible pediatric heart transplant shown to be as effective as the traditional approach

A pediatric heart transplant procedure pioneered by Canadian doctors--once deemed impossible--has been shown to be at least as effective as the traditional approach, according to newly published research in The Lancet Child & Adolescent Health.
Tags: Health

Therapeutic bed can help keep premature babies' brain oxygen levels steady during procedures

A medical device that has been shown to manage pain among babies born preterm can also help keep their brain oxygen levels steady during medical procedures, finds new analysis by researchers at UBC.
Tags: Health

New technology to obtain 'protein fingerprints' in just a few minutes

Researchers from Charité - Universitätsmedizin Berlin and the Francis Crick Institute have developed a mass spectrometry-based technique capable of measuring samples containing thousands of proteins within just a few minutes.
Tags: Health, Francis Crick Institute, Charité Universitätsmedizin Berlin

Study may provide an explanation for dawn phenomenon in patients with type 2 diabetes

Researchers at Baylor College of Medicine, Shandong University in China and other institutions may have found an explanation for dawn phenomenon, an abnormal increase of blood sugar only in the morning, observed in many patients with type 2 diabetes.
Tags: Health

First-of-its-kind project to disseminate bundled interventions for Black women with HIV

The University of Massachusetts Lowell, in collaboration with AIDS United, and the Center for Innovation in Social Work & Health at Boston University's School of Social Work (BUSSW), have been tapped to lead a national, first-of-its-kind project to evaluate and disseminate bundled evidence-informed and trauma-informed interventions for Black women with HIV.
Tags: Health, University of Massachusetts Lowell, Center for Innovation in Social Work Health, Boston University s School of Social Work BUSSW

Scientists reveal salivary gland cells as sites of COVID-19 infection

Scientists have shown that SARS-CoV-2, the virus that causes COVID-19, can infect specific cells in the salivary gland in the mouth.
Tags: Health

Study examines the health effects of diet and resistance training in middle-aged adults

A 10-week muscle-building and dietary program involving 50 middle-aged adults found no evidence that eating a high-protein diet increased strength or muscle mass more than consuming a moderate amount of protein while training.
Tags: Health

Duke-NUS professor and his team receive two awards at the International Stroke Conference 2021

Professor David Matchar and his team from the Health Services and Systems Research Programme at Duke-NUS Medical School, Singapore, bagged two prestigious awards at the International Stroke Conference 2021 for their project on a randomised controlled trial investigating the effects of incentives on improving the uptake of outpatient rehabilitation services (ORS) among stroke patients in Singapore.
Tags: Health, Singapore, Duke NUS Medical School, Duke NUS, David Matchar, Health Services and Systems Research Programme

Resolving an argument is important for maintaining well-being in daily life

A recent Oregon State University study found that when people feel they have resolved an argument, the emotional response associated with that disagreement is significantly reduced and, in some situations, almost entirely erased.
Tags: Health, Oregon State University

Study identifies NCOA3 as a novel therapeutic target for melanoma

For the first time, activation of nuclear receptor coactivator 3 (NCOA3) has been shown to promote the development of melanoma through regulation of ultraviolet radiation (UVR) sensitivity, cell cycle progression and circumvention of the DNA damage response.
Tags: Health

Vigorous exercise can modulate various parameters associated with improved sleep

Physical exercise has long been prescribed as a way to improve the quality of sleep. But now, researchers from Japan have found that even when exercise causes objectively measured changes in sleep quality, these changes may not be subjectively perceptible.
Tags: Health, Japan

Vaccine hesitancy could pose a major threat to public health efforts to end COVID-19

Although demand for COVID-19 vaccines currently seems high, vaccine hesitancy could pose a major threat to public health efforts to end the pandemic, according to an editorial published today in the journal Science.
Tags: Health

Corticotropin-releasing stress hormone may be linked to increased allergic reactions

Increased allergic reactions may be tied to the corticotropin-releasing stress hormone (CRH), suggests a study published this month in the International Journal of Molecular Sciences.
Tags: Health, Crh

Study identifies gene variants that cause metabolic deficiency in the eye

Treatments for a rare retinal disease may be on the horizon after a new study has identified gene variants that cause a metabolic deficiency in the eye.
Tags: Health

Why this plastic surgeon chose to become a high school science teacher [PODCAST]

“I have closed my practice, but I have no plans to retire at the age of 52. I have started the journey to become a high school science teacher. There are frequent internet postings and blogs by physicians with strategies to retire young. I suspect that many of us, not near traditional retirement age, still […] Find jobs at Careers by Search thousands of physician, PA, NP, and CRNA jobs now. Learn more.
Tags: Health, Podcast, Surgery, PA NP, CRNA

Oncotarget publishes phase 1 study of Z-Endoxifen in patients with advanced cancers

Oncotarget published "Phase 1 study of Z-Endoxifen in patients with advanced gynecologic, desmoid, and hormone receptor-positive solid tumors" which reported that Z-endoxifen administration was anticipated to bypass these variations, increasing active drug levels, and potentially benefiting patients responding sub-optimally to tamoxifen.
Tags: Health

INRS project receives major funding to assess the risks of well contamination in Madagascar

The project of Professor Geneviève Bordeleau, from the Institut national de la recherche scientifique, received financial support from the Quebec government under the International Climate Cooperation Program, a program of the 2013-2020 Action Plan on Climate Change, which was succeeded by the 2030 Plan for a Green Economy.
Tags: Health, Madagascar, Geneviève Bordeleau, International Climate Cooperation Program

Study shows substantial benefit of combination therapy for advanced Marburg infections

A new study conducted at the Galveston National Laboratory at the The University of Texas Medical Branch at Galveston has shown substantial benefit to combining monoclonal antibodies and the antiviral remdesivir against advanced Marburg virus.
Tags: Health, Galveston, The University of Texas Medical Branch, Galveston National Laboratory

Lupus Research Alliance announces recipients of the 2020 Distinguished Innovator Award

The Lupus Research Alliance proudly announces two exceptional recipients of the 2020 Dr. William E. Paul Distinguished Innovator Award in Lupus and Autoimmunity: Jacques Banchereau, PhD and Ignacio Sanz, MD.
Tags: Health, Lupus Research Alliance, William E Paul, Jacques Banchereau, Ignacio Sanz

UB receives $1.5 million grant to develop new therapies for oral cancers

The University at Buffalo has received a $1.5 million grant from the United States Department of Defense to develop new therapies that help reduce chronic inflammation and immunosuppression in oral cancers.
Tags: Health, UB, University at Buffalo, United States Department of Defense

ColoradoSPH wins NIH grant to study how air pollutants impact kidney health of sugarcane workers

Three groups from the Colorado School of Public Health have been awarded a $3 million 5-year grant from the National Institutes of Health to study the effects of air pollution and climate on the kidney health of sugarcane workers in Guatemala.
Tags: Health, National Institutes of Health, Nih, Colorado School of Public Health

UCLA researchers receive NIH grants to identify new ways to treat pancreatic cancer

A team of researchers from the UCLA Jonsson Comprehensive Cancer Center has been awarded two research grants totaling $6 million from the National Institutes of Health to identify new ways to treat pancreatic cancer.
Tags: Health, National Institutes of Health, Nih, Ucla, UCLA Jonsson Comprehensive Cancer Center

Study shows persisting cognitive benefits of common Alzheimer’s treatment

Cholinesterase inhibitors are a group of drugs recommended for the treatment of Alzheimer's disease, but their effects on cognition have been debated and few studies have investigated their long-term effects.
Tags: Health

Physically active people recover better after colorectal cancer surgery

People who are physically active on a regular basis recover better after surgery for colorectal cancer. However, starting to exercise only after the diagnosis is a fact had no effect on recovery, a University of Gothenburg thesis shows.
Tags: Health, University of Gothenburg

Five Great and Helpful Ways To Feel Fit Again

We all want to feel good in our bodies but when we don’t, it can really impact our lives in many ways. Not only that but mentally, it can have an effect on your body. It’s important that you’re finding the fitness you love, the right balance of good and not-so-good foods to eat, and ensuring that things in life aren’t going to stress you out too much that they make you ill. Here are five ways to feel fit again. Start Off Small Firstly, always start off small where you can. It’s important tha...
Tags: Health, Fitness, Jazz, Feel Fit Again

Smoking cessation therapy for hospitalized patients may help avoid many premature deaths

Smoking cigarettes causes 480,000 premature deaths each year in the United States, due mainly to a two-fold risk of cardiovascular disease and a 20-fold risk of lung cancer. Although smoking rates have declined dramatically, there are currently 35 million smokers in the U.S.
Tags: Health, United States

FDA approves new indication for drug to treat pediatric NDO patients

Today, the U.S. Food and Drug Administration approved a new indication for Myrbetriq (mirabegron extended-release tablets) and Myrbetriq Granules (mirabegron for extended-release oral suspension) to treat neurogenic detrusor overactivity (NDO), a bladder dysfunction related to neurological impairment, in children ages three years and older.
Tags: Health, Fda, U S Food and Drug Administration

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