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How often do vaccine trials hit paydirt?

Vaccines are more likely to get through clinical trials than any other type of drug — but have been given relatively little pharmaceutical industry support during the last two decades, according to a new study by MIT scholars.Over a two-decade span from January 2000 to January 2020, private-sector vaccine-development efforts succeeded in bringing a drug to market 39.6 percent of the time, the researchers found. By contrast, programs to develop anti-infective therapeutics — medicines that lessen ...
Tags: Health, Mit, Medical Research, Innovation, Vaccines, Epidemiology, Zika, Lo, National Bureau of Economic Research NBER, MIT Sloan School of Management, Charles E, Pandemic, Andrew Lo, Susan T Harris, MIT Laboratory for Financial Engineering, Coronavirus


Bubonic plague case reported in China

The case was reported in the city of Bayannur, which has issued a level-three plague prevention warning.Modern antibiotics can effectively treat bubonic plague, which spreads mainly by fleas.Chinese health officials are also monitoring a newly discovered type of swine flu that has the potential to develop into a pandemic virus. A man in China's inner Mongolia region was infected with bubonic plague, according to health officials.The infection occurred in the city of Bayannur, located northwest ...
Tags: Health, Colorado, China, Innovation, Disease, China Daily, Centers For Disease Control And Prevention, Mongolia, National Academy of Sciences, New Mexico Arizona, Stanford Health Care, Beijing city, Coronavirus, Bayannur, Shanthi Kappagoda


Why is everyone so selfish? Science explains

Selfish behavior has been analyzed by philosophers and psychologists for centuries.New research shows people may be wired for altruistic behavior and get more benefits from it.Crisis times tend to increase self-centered acts. Why do so many people seem so selfish these days, putting their needs first? The coronavirus has not only decimated our population and placed lives on anxious hold, it has also been a test of character. A test that, by and large, we appear to be failing. People are at each...
Tags: Psychology, Politics, Society, Brain, Yale, Innovation, Consciousness, Mind, Paul Krugman, Ucla, Self, Social Psychology, Yale University, Nature Communications, Peter Singer, University of Zurich


Creativity: The science behind the madness

An all-star cast of Big Thinkers—actors Rainn Wilson and Ethan Hawke; composer Anthony Brandt; neuroscientists David Eagleman, Wendy Suzuki, and Beau Lotto; and psychologist Scott Barry Kaufman—share how they define creativity and explain how our brains uniquely evolved for the phenomenon. According to Eagleman, during evolution there was an increase in space between our brain's input and output that allows information more time to percolate. We also grew a larger prefrontal cortex which "allows...
Tags: Psychology, Art, Design, Biology, Writing, Neuroscience, Play, Brain, Creativity, Innovation, Ethan Hawke, Fear, Evolution, Mind, Personal Growth, Rainn Wilson


New study explores how to navigate 'desire discrepancies' in long term relationships

A new study highlights the difficulties faced by women who struggle with decreased sexual desire, and explains how to navigate desire discrepancies in long-term relationships. Hypoactive sexual desire disorder is one of the most common forms of female sexual dysfunction, impacting an estimated 1 in 10 women.Finding other ways to promote intimacy in your relationship is one of the keys to ensuring happiness on both sides. The loss of sexual desire is something that can impact anyone, no matter th...
Tags: Psychology, Marriage, Sex, Relationships, Love, Women, Compassion, Mental Health, Innovation, Emotions, Harvard Medical School, Avigail Moor, Yael Haimov, Shaked Shreiber, Shifren


Americans officially banned from entering EU, at least for now

The European Union made an agreement on a list of 15 countries that could travel in its bloc from July 1st.Citizens of the United States, as well as Russia, Brazil and India, are not on it.The exclusion of the U.S. reflects concerns over its coronavirus surge. From July 1st, when its external borders will re-open, American tourists won't be welcome in Europe, decrees a new agreement from the European Union. The bloc decided on a list of 15 safe countries whose residents would be allowed to trav...
Tags: Travel, Health, Europe, Politics, Medicine, Congress, Cdc, China, Russia, India, Eu, European Union, Public Health, United States, Innovation, Epidemics


As belly size gets larger, the memory center in the brain gets smaller

Researchers at University College London have discovered a link between waist circumference and dementia. Seventy-four percent of volunteers that developed dementia were overweight or obese.Women with central obesity had a 39 percent greater risk of dementia. One of every eight deaths in England was attributed to dementia in 2017. Considering the substantial public health burden this adds to a society, researchers at University College London wanted to understand the role of obesity on cognitiv...
Tags: Health, England, London, Aging, Women, Innovation, Dementia, Ucl, Mediterranean, University College London, Derek, Epidemiology, University College, Twitter Facebook, International Journal of Epidemiology, Weill Cornell Medical College


Pop-up wearable tent for COVID-19 protection in offices, schools, and medical facilities

A few years back, my brother Rick Pescovitz came up with Under The Weather Pods, single-person pop-up shelters. (You may have caught Rick on Shark Tank.) Rick was sick of getting soaked at his kids' soccer games and was inspired by a portable toilet he saw by the field. Under The Weather Pods are designed for watching sports, fishing, and other outdoor events where it's raining, windy, or cold, but you are either obligated to watch or having so much fun you don't want to leave. When the pa...
Tags: Health, Post, Design, News, Medical, Innovation, Kelly, Rick, Rick Pescovitz, COVID-19


The psychology of narcissism explained

Narcissistic personality disorder is one of several types of personality disorders. It is characterized as a mental condition in which people have an inflated sense of self.According to the most recent data, narcissistic personality disorder isn't as common as we think, impacting an estimated 1 percent of our population. The confusion lies in how we define the disorder compared to other narcissistic personality traits.Dr. Ramani Durvasula explains that we need a clearer definition of what this d...
Tags: Psychology, Relationships, Empathy, Mental Health, Brain, Personality, Innovation, Emotions, Mind, Self, Personal Growth, Santa Monica California, NPI, Durvasula, Ramani Durvasula, Preston Ni


Antidepressants linked to increased suicide and self-harm in teens

Australian researchers note a link between rising antidepressant usage and rising suicide rates in youth. Their research pushes back on psychiatry talking points that SSRIs decrease suicide risk. The top method for self-harm and suicide in younger age groups is overdosing antidepressants. In 1947, Dr Howard Rusk published an article in the NY Times. The doctor is advocating for better public education on issues of mental health. Considered to be the founder of rehabilitation medicine, Rusk was...
Tags: Psychology, Australia, Youth, US, America, Mental Health, Depression, Psychiatry, Medical Research, Innovation, New South Wales, Adelaide, Fda, OECD, Perth, Derek


Dating over Zoom? Don’t be surprised if those online sparks fizzle in person

For those dipping their toes into the dating pool during stay-at-home orders, it's been like swimming in a version of Netflix's reality series “Love is Blind." In the show, contestants must get engaged before ever actually meeting one another in person. And while a lockdown engagement might be a bit extreme, it's entirely possible that two people have grown to really like one another over the previous weeks and months. Maybe it started with a match on a dating app, followed by flirting over text...
Tags: Psychology, Sex, Relationships, Love, Web, Netflix, Innovation, Body Language, University of Albany


The 'Western diet' is linked to adult acne in a new study

University of Paris researchers found that the consumption of fatty and sugary products, sugary beverages, and milk seems to increase adult acne. The team used data from over 24,000 participants in a famous French study. Roughly 50 percent of adults in Western countries over age 25 suffer from acne. The bane of adolescence can be a lifetime recurrence with the wrong diet. According to a new study, published in JAMA Dermatology, the Western diet is associated with an increased likelihood of adul...
Tags: Psychology, Health, Biology, Happiness, Acne, Medical Research, Paris, Innovation, Derek, Skin, Twitter Facebook, IGF, University of Paris, Human body, NutriNet Sante, Drew Ramsey


Europe to ban American travel as U.S. struggles to contain pandemic

The EU has slowed the spread of COVID-19 in most regions, while cases in the U.S. continue to grow.The U.S. is reportedly excluded from both lists of "accepted nations," but Secretary of State Mike Pompeo suggested the U.S. may reach an agreement with European officials.A ban on American travel would surely have political consequences for the Trump administration. The European Union is preparing to block Americans from traveling to member nations when borders begin to reopen on July 1.European ...
Tags: Travel, Health, Europe, Florida, Eu, European Union, United States, Innovation, Oklahoma, Donald Trump, Trump, State, Texas California, Pompeo, Disease Prevention and Control, Mike Pompeo


Man unable to 'see' numbers after suffering rare brain disease

When a man who was diagnosed with the neurodegenerative disease corticobasal syndrome looks at the numbers 2 through 9, he sees unintelligible squiggly lines.The disability appears to be a peculiar type of metamorphopsia, a visual defect that causes linear objects, like the lines on a grid, to look curvy or rounded.The study has some interesting implications on theories of consciousness. Someone writes the number 8 on a piece of paper. You look at it, see a shape, but you can't identify what nu...
Tags: Health, Brain, Medical Research, Harvard University, Innovation, Consciousness, National Academy of Sciences PNAS, Michael McCloskey, Teresa Schubert


What is an immunity passport and could it work?

Weeks into lockdown and with economic indicators signalling a deep global recession, governments around the world are searching for ways to get their countries back up and running. But emerging from a cocooned state could risk a second spike of coronavirus infections as people start mixing once more. Among the measures being considered by governments including Chile, Germany, Italy, Britain and the US are immunity passports – a form of documentation given to those who have recovered from COVID-1...
Tags: Health, US, Public Health, Medical Research, Chile, Innovation, Who, Epidemiology, World Health Organization WHO, Phelan, International Labour Organization, Georgetown University, Pandemic, Coronavirus, COVID, Center for Global Health Science and Security


New research suggests biases play a role in FDA drug approval

When new drugs are similar to popular drugs on the market, FDA approval takes up to 75 percent longer. Texas McCombs Professor Francisco Polidoro Jr. reviewed 291 drugs over a 35-year period. Polidoro believes that potential coronavirus treatments or vaccines could help the FDA improve upon this longstanding bias. Speaking in front of Congress earlier this week, Dr. Anthony Fauci said he is "cautiously optimistic" that a coronavirus vaccine will be developed. He believes "it will be when and n...
Tags: Psychology, Texas, Congress, Virus, Medical Research, Innovation, Fda, Health Care, Anthony Fauci, Derek, Twitter Facebook, Strategic Management Journal, Robert Whitaker, Coronavirus, COVID-19, Francisco Polidoro Jr


Want better sex? Science says show more gratitude

A new study shows that people who express and receive gratitude from their partners are more motivated to meet their sexual needs. The effect was also seen with the mere perception of gratitude. As science is increasingly coming to understand, gratitude has many more benefits than this. A new study finds that people who appreciate and are appreciated by their partners are more motivated to respond to their partner's sexual needs than those in relationships marked by a lack of mutual gratitude. T...
Tags: Psychology, Sex, Relationships, Communication, Compassion, Innovation, North Carolina, Cicero, SCS, Greensboro, Ashlyn Brady


Horror video games may have therapeutic value

Some of the most downloaded video game genres during the pandemic quarantine have been horror games designed to inspire terror and anxiety.Authors of a new study say that inserting yourself into a virtual horror realm could offer relief during times of stress by allowing you to engage and dominate materialized monsters and demons. They argue that the horror game appeal is similar to religious methods to grapple with fear and guilt (sin). A befuddling trend in the world of gaming culture has e...
Tags: Psychology, Gaming, Video Games, Horror, Religion, Innovation, Fear, Coronavirus


The psychology of psychopathy: An inside look at the psychopathic brain

According to a 2017 study led by the University of Wisconsin-Madison, psychopaths have reduced connections in the areas of the brain that control fear, anxiety, empathy and sentimentality.Psychopathy is typically diagnosed using a 20-item checklist called the Hare Psychopathy Checklist.Psychopathic tendencies could be considered "warning signs" of psychopathy, but it's important to note that not everyone who shows psychopathic tendencies becomes a psychopath. Psychopathy is defined as a conditio...
Tags: Psychology, Empathy, Mental Health, Genetics, Personality, Innovation, Fear, Emotions, Mind, David Mitchell, University of Wisconsin Madison, Ramirez, Beth, Ted Bundy, Beth Thomas


Weight gain affects the efficacy of antidepressants, new study finds

A comprehensive scoping review of 12 studies found that being overweight negatively affects the efficacy of antidepressants.McGill University researchers investigated SSRIs, SNRIs, tricyclic antidepressants, and tetracyclic antidepressants. A double-edged sword: obesity impacts antidepressants, yet a side effect of these drugs is weight gain. The initial European trials for gaboxadol produced positive results. Merck and Lundbeck were convinced they had a blockbuster drug on their hands. Resear...
Tags: Psychology, Biology, US, Merck, Mental Health, Depression, Psychiatry, Medical Research, Innovation, Who, Mcgill, Derek, McGill University, Twitter Facebook, Julie Holland, Lundbeck


Inside the brains of psychopaths

How are the brains of psychopaths wired differently? In this video, psychologist Kevin Dutton, neuroscientist (and psychopath himself) James Fallon, and professor of psychiatry Michael Stone take the wiring apart. In neurotypical people, the amygdala and the orbitofrontal cortex inhibit one another to allow for reasonable, moral decision-making. Psychopaths don't have that mechanism. Up to 80% of who a psychopath will turn out to be is down to environment. Intelligence, natural aggressiven...
Tags: Psychology, Decision Making, Science, Crime, Relationships, Neuroscience, Intelligence, Empathy, Mental Health, Brain, Personality, Innovation, Fear, Violence, Emotions, Psychopath


The insane problem of US standardized testing

When it comes to elements of the US education system that simply don't work, there is one controversial topic that educators always come back to: standardized testing.For Rosalind Wiseman, best-selling author and founder of Cultures of Dignity, using standardized tests as the ultimate barometer of a student's worth (and of the quality of education provided by an institution), and perpetuating that system for profit, is not only problematic and inaccurate, it is "criminal" and "irresponsible."The...
Tags: Learning, Education, Children, Youth, Future, US, Teaching, Mental Health, Capitalism, Testing, Innovation, Rosalind Wiseman, Future Of Learning


Remote working is the new norm—work-life balance is more important than ever

Over the last decade, remote working has become more and more popular. Now, because of the COVID-19 pandemic, up to 62% of people are now working from home.Up to 40% of survey respondents say they feel more productive while working from home. However, there are also negative impacts, such as not taking as many breaks. "Employee burnout" is increasing at an alarming rate.Telecommuting and remote working will be the norm long after the pandemic, according to many outlets. There are things we can d...
Tags: Psychology, Health, Work, Productivity, Europe, Mindfulness, Mental Health, United States, Work-life balance, Innovation, New Zealand, Emotions, Personal Growth, Across


This Kickstarter-funded brass stylus helps you avoid germs in public places

The CDC says your hands spread germs on objects like tables, ATM machines, elevator buttons, and door handles.Hygiene Hand is a tool to help avoid direct contact with shared surfaces.After a successful funding round on Kickstarter, the Hygiene Hand is now available to everyone. You've likely never washed your hands as much as you have in these last few months. But sadly, not everyone is as vigilant about hand-washing as you are. As the CDC warns, hands can leave germs on numerous objects—tablet...
Tags: Health, Science, Cdc, Virus, Innovation, Invention, Edc, Hunter, Coronavirus, StatGear Hygiene Hand, Hygiene Hand


New bandages turn color to identify an infected wound

Judicious use of drugs for resistant bacteria requires time- and money-consuming tests until now.New smart bandages turn red for resistant bacteria and yellow for antibiotic-sensitive bacteria.The bandages also promote healing with the application of UV light. The growing incidence of antibiotic-resistant bacteria was already a worrying problem before we all started washing our hands with anti-bacterial soaps in response to SARS-CoV-2. While necessary, we may also have provided even more bacter...
Tags: Health, Medicine, Bacteria, Medical Research, Innovation, Invention, Health Care, Microbes, Coli, Smart bandaid, Chinese Academy of Sciences Changchun Jilin


Free self-hypnosis therapy in your home? Just ask Alexa

Hypnosis refers to a trance state that is characterized by extreme suggestibility, relaxation, and heightened imagination.Hypnotherapy can be used to help you quit smoking, to manage chronic and acute pain, during labor and childbirth, as well as to ease stress and anxiety.Reveri Health, headed by Ariel Poler and Dr. David Spiegel, has launched several self-hypnosis skill programs through Amazon Alexa and Google Assistant, one of which is designed to combat the anxiety surrounding the COVID-19 g...
Tags: Psychology, Google, Science, Mental Health, Brain, Therapy, United States, Innovation, Fear, Consciousness, Visualizations, Emotions, Mind, Hypnosis, Stanford University, Alexa


LIVE TOMORROW | Do the 'Great Midlife Edit' with Airbnb alum Chip Conley

Add event to your calendar Aging is inevitable, but it doesn't have to be so taboo. After helping turn AirBnB into a multi-billion-dollar business, hospitality maverick Chip Conley founded the Modern Elder Academy, the world's first midlife wisdom school. In this Big Think Live session, Conley will explain why the term 'elder' must be reclaimed, how to make the absolute best of your career at this stage, and how to conduct the 'Great Midlife Edit' to boost your happiness. Ask your question...
Tags: Health, Career, Facebook, Identity, Life, Aging, Happiness, Success, Innovation, Chip Conley, Personal Growth, Conley, Modern Elder Academy


Midlife crisis? More like midlife calling. Here's how to find yours.

Add event to your calendar Aging is inevitable, but it doesn't have to be so taboo. After helping turn AirBnB into a multi-billion-dollar business, hospitality maverick Chip Conley founded the Modern Elder Academy, the world's first midlife wisdom school. In this Big Think Live session, Conley will explain why the term 'elder' must be reclaimed, how to make the absolute best of your career at this stage, and how to conduct the 'Great Midlife Edit' to boost your happiness. Ask your question...
Tags: Health, Career, Facebook, Identity, Life, Aging, Happiness, Success, Innovation, Chip Conley, Personal Growth, Conley, Modern Elder Academy


10 lessons from the COVID-19 frontline for a more gender-equal world

Evidence shows that disease outbreak affects women and men differently, that pandemics exacerbate inequalities for girls and women, who are also often the hardest hit, and that women play an outsize role responding to crises, including as frontline healthcare and social workers, caregivers at home, and as mobilizers in their communities.That's why the world must put a gender lens on the response to COVID-19, to ensure the unique needs of girls and women are addressed, and their unique expertise ...
Tags: Health, Gender, Women, Innovation, Women In Business, Inequality, Coronavirus, COVID


Do antidepressants create more mental illness than they cure?

Many antidepressants show no better efficacy than placebo or talk therapy in long-term usage. Proselytizing pharmaceutical interventions has been part of a concerted effort since the 1970s. Journalist Robert Whitaker discusses the impact of pathologizing children, moral therapy, and more. Doctors wrote a record number of prescriptions for Zoloft in March, causing the FDA to add this SSRI to its drug shortage list. Zoloft prescriptions then dropped in April—4.5 million, down from 4.9 million—ye...
Tags: Psychology, Nigeria, US, America, Mental Health, Depression, Anxiety, Harvard, Innovation, World Health Organization, Fda, Psychotherapy, Robert, Derek, Boston Globe, American Medical Association



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