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Mount Sinai awarded $12.5 million NIH grant for research program in aging biology

Researchers from the Icahn School of Medicine at Mount Sinai have been awarded a $12.5 million grant from the National Institute on Aging, part of the National Institutes of Health, for a five-year program called the U19 that consists of four multidisciplinary projects in aging biology.
Tags: Health, Mount Sinai, Icahn School of Medicine


Prior dengue virus infection increases Zika virus-induced damage during pregnancy

Women who have previously been infected with dengue virus may be at risk for increased damage to their fetuses and placentas if they should later become infected with the Zika virus, researchers from the Department of Microbiology at the Icahn School of Medicine at Mount Sinai report.
Tags: Health, Mount Sinai, Zika, Icahn School of Medicine, Department of Microbiology


New prostate cancer prediction tool has unmatched accuracy

A team of researchers from the Icahn School of Medicine at Mount Sinai and Keck School of Medicine at the University of Southern California have developed a novel machine-learning framework that distinguishes between low- and high-risk prostate cancer with more precision than ever before.
Tags: Health, University Of Southern California, Mount Sinai, Icahn School of Medicine, Keck School of Medicine


Honest Company co-founder Christopher Gavigan has a new, and newly funded, CBD startup called Prima

Christopher Gavigan, sitting in a crisp white shirt inside a small TechCrunch conference room, radiates energy, even in a late-day interview just hours before he’s scheduled to fly home from San Francisco to L.A. We’re meeting to talk about Prima, a new startup that Gavigan began developing seven months ago with two co-founders. One of them is a former beauty and marketing executive, Jessica Assaf, who was until recently running a company called Cannabis Feminist to sell marijuana wellness pr...
Tags: Health, Startups, TC, California, Oregon, New York City, San Francisco, Tech, Atlantic, United States, Fda, Honest Company, Greycroft, Ucla, Southern California, Mount Sinai


Mount Sinai joins with Paradigm and ReqMed to repurpose drug for treatment of MPS

The Icahn School of Medicine at Mount Sinai has entered into two exclusive licenses to develop the drug pentosan polysulfate sodium for and ReqMed Company, Ltd. of Japan.
Tags: Health, Mount Sinai, Icahn School of Medicine, ReqMed Company Ltd


Study shows how herpes viruses and tumors have learned to manipulate the same ancient RNA

Herpes viral infections use the ancient genetic material found in the human genome to proliferate, mimicking the same process tumors have been found to manipulate, Mount Sinai researchers have shown for the first time.
Tags: Health, Mount Sinai


Whole genome study identifies genetic architecture for diagnosis of polycystic ovary syndrome

In the largest genetic analysis of polycystic ovary syndrome (PCOS) performed to date, an international consortium, including researchers at the Icahn School of Medicine at Mount Sinai, conducted a whole genome association study to identify common genetic architecture for different diagnostic criteria used to define the syndrome.
Tags: Health, Mount Sinai, Icahn School of Medicine


Mount Sinai researcher awarded $2.5 million to advance understanding of neurodegenerative diseases

Ivan Marazzi, PhD, Assistant Professor of Microbiology at the Icahn School of Medicine at Mount Sinai, was awarded $2.5 million in funding by the Chan Zuckerberg Initiative to further the understanding of the underlying causes of neurodegenerative disorders such as Lou Gehrig's, Alzheimer's, and Parkinson's diseases. The
Tags: Health, Chan Zuckerberg Initiative, Mount Sinai, Lou Gehrig, Icahn School of Medicine, Ivan Marazzi


Study evaluates second-hand marijuana smoke exposure among children

In a study designed to evaluate second-hand marijuana smoke exposure among children--a topic that scientists have not yet widely addressed--researchers at the Icahn School of Medicine at Mount Sinai found that nearly half of children whose parents smoked marijuana showed evidence of second-hand marijuana smoke exposure.
Tags: Health, Mount Sinai, Icahn School of Medicine


Researchers develop tool that speeds up analysis and publication of biomedical data

Researchers at the Icahn School of Medicine at Mount Sinai have developed a tool that speeds up the analysis and publication of biomedical data from many months or years to mere minutes, transforming the way researchers communicate results of their studies.
Tags: Health, Mount Sinai, Icahn School of Medicine


Psychology Around the Net: November 3, 2018

This week’s Psychology Around the Net takes a look at what your reaction to WiFi failure says about your personality, the psychology of faking your own death, why reading could be the key to breaking free from chronic loneliness (and all the health risks loneliness brings), and more. ‘Darkitecture’: The Art and Psychology of Haunted House Design: Did you visit any haunted houses for Halloween, or maybe plan to this weekend? If you’re lucky (i.e. want the potentially scariest experience possible...
Tags: Psychology, UK, Mount Sinai, Icahn School of Medicine, Knox College, Frank T McAndrew, Seaver Autism Center for Research and Treatment


Researchers find key differences in brains of males and females with schizophrenia

Researchers from the Icahn School of Medicine at Mount Sinai have found clear disparities in the way males and females--both those with schizophrenia and those who are healthy--discern the mental states of others.
Tags: Health, Mount Sinai, Icahn School of Medicine


Lifespan vs. healthspan: "I'LL do it" mnemonic

Epigenetics"Tthere is nobody who disputes that epigenetics predicts life span”. Aging eight or more years faster than your calendar age equates to twice the typical risk of dying, while aging seven years slower is associated with half the risk of death, Horvath says."Life span predictor" clockHis lab has developed a "life span predictor" they named it after the Grim Reaper: DNAm GrimAge. The epigenetic clock is more accurate the younger a person is. It’s especially inaccurate for the very old. “...
Tags: Health, Facebook, New York City, Lifestyle, Mount Sinai, Icahn School of Medicine, Horvath, Ves Dimov, Geriatrics, Diane Meier


Researchers design modeling system to infer relationships between genes, drugs, and their environment

A team of researchers at the Icahn School of Medicine at Mount Sinai and the University of Washington has designed a modeling system that integrates genomic and temporal information to infer causal relationships between genes, drugs, and their environment, allowing for a more accurate prediction of their interactions over time.
Tags: Health, Mount Sinai, University of Washington, Icahn School of Medicine


Excessive use of erectile-dysfunction medication could lead to long-term vision problems

In a first-of-its-kind study, Mount Sinai researchers have shown that color vision problems caused by retinal damage on a cellular level can result from a high dose of sildenafil citrate, the popular erectile-dysfunction medication sold under the brand name Viagra.
Tags: Health, Mount Sinai


TEAD1 protein appears to be important regulator of tumor migration in glioblastoma

A specific protein called TEAD1 is an important regulator of tumor migration in glioblastoma, the most common brain tumor in adults, and deactivating this protein may stop tumor cells from migrating away from the main tumor mass, according to research conducted at the Icahn School of Medicine at Mount Sinai and published October 1 in the journal Nature Communications.
Tags: Health, Mount Sinai, Icahn School of Medicine


Study offers solid link between visceral organs and brain’s reward, motivation system

A novel gut-to-brain neural circuit establishes the vagus nerve as an essential component of the brain system that regulates reward and motivation, according to research conducted at the Icahn School of Medicine at Mount Sinai and published September 20 in the journal Cell.
Tags: Health, Mount Sinai, Icahn School of Medicine


Study: Women exposed to trauma in their lives gave birth to underweight male infants

In the first study of its kind, researchers from the Icahn School of Medicine at Mount Sinai have found significantly lower birth weights in male infants--an average decrease of 38 grams, or approximately 1.3 ounces--born to women who had been exposed to trauma at some point in their lives and who secreted higher levels of cortisol, a hormone related to stress, in late pregnancy.
Tags: Health, Mount Sinai, Icahn School of Medicine


Researchers discover reason why many bladder cancer patients do not respond to immunotherapy

Mount Sinai researchers have discovered that a particular type of cell present in bladder cancer may be the reason why so many patients do not respond to the groundbreaking class of drugs known as PD-1 and PD-L1 immune checkpoint inhibitors, which enable the immune system to attack tumors.
Tags: Health, Mount Sinai


Researchers find new therapy to prevent drug resistance for melanoma patients

Mount Sinai researchers have discovered a previously unknown reason for drug resistance in a common subtype of melanoma, one of the deadliest forms of cancer, and in turn, have found a new therapy that could prevent or reverse drug resistance for melanoma patients with a particular gene mutation, according to a study published in Nature Communications in August.
Tags: Health, Mount Sinai, Nature Communications


Mount Sinai study could transform treatment for patients with retinal degenerative diseases

Researchers at Mount Sinai have successfully restored vision in mice through activating retinal stem cells, something that has never been done before. Their study, published in the August 15 online issue of Nature, could transform treatment for patients with retinal degenerative diseases, which currently have no cure.
Tags: Health, Mount Sinai


Researchers identify way to grow immune cells at large scale for preventing cancer reoccurrence

For the first time, Mount Sinai researchers have identified a way to make large numbers of immune cells that can help prevent cancer reoccurrence, according to a study published in August in Cell Reports.
Tags: Health, Mount Sinai


Innovative oncofertility program launched by RMA of New York and Mount Sinai Health System

Reproductive Medicine Associates of New York, a Manhattan-based fertility center, and the Mount Sinai Health System have launched an innovative, integrated oncofertility program at The Blavatnik Family – Chelsea Medical Center at Mount Sinai to provide individuals and couples the benefit of advanced medical technologies to help with someday building their families.
Tags: Health, New York, Manhattan, Mount Sinai, RMA, Mount Sinai Health System, Reproductive Medicine Associates of New York, Chelsea Medical Center


NIH grant for Mount Sinai to study use of inhaled corticosteroids for treatment of sickle cell disease

The Departments of Emergency Medicine and Hematology at the Icahn School of Medicine at Mount Sinai have been awarded a $4 million grant from the National Institutes of Health toward further study of inhaled corticosteroids to treat sickle cell disease in individuals who do not have asthma.
Tags: Health, National Institutes of Health, Nih, Mount Sinai, Icahn School of Medicine, Emergency Medicine and Hematology


Switching anti-psychotic drugs in first-episode schizophrenia patients does not improve clinical outcomes

Switching anti-psychotic medications does not improve clinical outcomes in patients with first-episode schizophrenia who haven't responded to treatment, Mount Sinai researchers have shown for the first time.
Tags: Health, Mount Sinai


AI platform identifies acute neurological illnesses faster than human diagnosis

An artificial intelligence platform designed to identify a broad range of acute neurological illnesses, such as stroke, hemorrhage, and hydrocephalus, was shown to identify disease in CT scans in 1.2 seconds, faster than human diagnosis, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published today in the journal Nature Medicine.
Tags: Health, Mount Sinai, Icahn School of Medicine


New drug cocktails make targeted cancer therapies more efficient with less side effects

Mount Sinai researchers have discovered that certain drug cocktails help targeted therapies attack cancer more efficiently while lessening common side effects, according to a study published today in Cancer Research.
Tags: Health, Mount Sinai


"New York’s CBD craze has already reached Dadaesque levels of consumerism—hundred-dollar tinctures to treat anxiety in pet cats and dogs; CBD-laced room service at the NoMad location of the James hotel, in Manhattan."

Explains Rachel Symes (at The New Yorker).Like many New Yorkers, I tend to be deeply wary of the nouveau-wellness movement that has crept into the city from L.A., with its Goopian buzzwords and mushroom tonics and colloidal silver—the idea that you can shop your way to an internal glow... But CBD, with its potential to unclench tense muscles and pacify anxious thoughts, also promises to deliver something that many New Yorkers desperately need....CBD is the hemp derivative that New Yorkers can ha...
Tags: Psychology, New York, Law, Marijuana, Commerce, Manhattan, James, Mount Sinai, Hurd, Ann Althouse, Rachel Symes


Mount Sinai study could help doctors to better understand and manage diseases affecting the larynx

In a first-of-its-kind study, Mount Sinai researchers have used sensory mapping to discover that the posterior part of the larynx (closest to the swallowing tract) is the main area of the voice box to protect the airway from potentially dangerous swallowed or inhaled substances.
Tags: Health, Mount Sinai


Researchers report unusually high levels of herpesvirus in the brains of people with Alzheimer's disease

Two strains of human herpesvirus-;human herpesvirus 6A (HHV-6A) and human herpesvirus 7 (HHV-7) -;are found in the brains of people with Alzheimer's disease at levels up to twice as high as in those without Alzheimer's, researchers from the Icahn School of Medicine at Mount Sinai report.
Tags: Health, Mount Sinai, Icahn School of Medicine



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