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New deep-learning framework predicts gene regulation at single-cell level

Scientists at the University of California, Irvine have developed a new deep-learning framework that predicts gene regulation at the single-cell level.
Tags: Health, University of California Irvine


How to Talk with a Conspiracy Theorist: What the Experts Recommend

https://www.youtube.com/watch?v=JpInOs1Fyno Why do people pledge allegiance to views that seem fundamentally hostile to reality? Maybe believers in shadowy, evil forces and secret cabals fall prey to motivated reasoning. Truth for them is what they need to believe in order to get what they want. Their certainty in the justness of a cause can feel as comforting as a warm blanket on a winter’s night. But conspiracy theories go farther than private delusions of grandeur. They have spilled i...
Tags: Psychology, Google, Politics, College, Current Affairs, Reddit, University of Pennsylvania, Vox, Bill Nye, Daniel, Facebook Twitter, Pew Research, Josh Jones, University of California Irvine, Cass Sunstein, MIT Technology Review


How to Talk with a Conspiracy Theorist (and Why People Believe Conspiracy Theories in the First Place): What the Experts Recommend

https://www.youtube.com/watch?v=JpInOs1Fyno Why do people pledge allegiance to views that seem fundamentally hostile to reality? Maybe believers in shadowy, evil forces and secret cabals fall prey to motivated reasoning. Truth for them is what they need to believe in order to get what they want. Their certainty in the justness of a cause can feel as comforting as a warm blanket on a winter’s night. But conspiracy theories go farther than private delusions of grandeur. They have spilled i...
Tags: Psychology, Google, Politics, College, Current Affairs, Reddit, University of Pennsylvania, Vox, Bill Nye, Daniel, Facebook Twitter, Pew Research, Josh Jones, University of California Irvine, Cass Sunstein, MIT Technology Review


Squelched by Twitter, Trump seeks new online megaphone

By FRANK BAJAK BOSTON (AP) — One Twitter wag joked about lights flickering on and off at the White House being Donald Trump signaling to his followers in Morse code after Twitter and Facebook squelched the president for inciting rebellion. Though deprived of his big online megaphones, Trump does have alternative options of much smaller reach, led by the far right-friendly Parler — even if Google removed it from its app store Friday and Apple threatened the same. Trump may launch his own platform...
Tags: Apple, Health, Google, Facebook, Twitter, Business, Technology, Media, Instagram, Congress, Youtube, Washington, White House, China, Germany, Boston


A machine-learning model created to calculate COVID-19 health outcomes

University of California, Irvine health sciences researchers have created a machine-learning model to predict the probability that a COVID-19 patient will need a ventilator or ICU care. The tool is free and available online for any healthcare organization to use.
Tags: Health, University of California Irvine


UCI researchers develop noninvasive, at-home saliva test to detect COVID-19

Researchers in the Henry Samueli School of Engineering at the University of California, Irvine announced promising results in the development of a noninvasive at-home antigen test to detect the spike of SARS-CoV-2 proteins in saliva.
Tags: Health, UCI, University of California Irvine, Henry Samueli School of Engineering


Using fractional exponents in epidemic models could improve predictions of disease spread

A new class of epidemiological models based on alternative thinking about how contagions propagate, particularly in the early phases of a pandemic, provide a blueprint for more accurate epidemic modeling and improved disease spread predictions and responses, according to a study published recently in Scientific Reports by researchers at the University of California, Irvine and other institutions.
Tags: Health, University of California Irvine


Smiling or grimacing can reduce the pain of needle injection by 40%

The coming of winter means cooler temperatures, shorter days and flu shots. While no one looks forward to a vaccination, a study led by the University of California, Irvine, has found that either a sincere smile or a grimace can reduce the pain of a needle injection by as much as 40 percent.
Tags: Health, University of California Irvine


Study reveals a previously undetected repertoire of cancer driver genes

A new study, led by researchers from the University of California, Irvine, has deepened the understanding of epigenetic mechanisms in tumorigenesis and revealed a previously undetected repertoire of cancer driver genes.
Tags: Health, University of California Irvine


Researchers estimate prevalence of SARS-CoV-2 antibodies among adults in orange county

Testing a representative sample of Orange County residents for a wide range of coronavirus antibodies, University of California, Irvine researchers found that 11.5 percent of them have antibodies for COVID-19, in contrast to previous estimates of less than 2 percent.
Tags: Health, Orange County, University of California Irvine


$109 million NIH grant awarded to expand Alzheimer's disease and Down syndrome research

The Alzheimer's Biomarkers Consortium - Down Syndrome, a multi-institution research team, co-led by members from the University of California, Irvine, has been awarded an unprecedented five-year, $109 million grant by the National Institutes of Health, to expand research on the biomarkers of Alzheimer's disease in adults with Down syndrome.
Tags: Health, National Institutes of Health, University of California Irvine


Study helps restore retinal and visual functions of mice models of inherited retinal disease

A breakthrough study, led by researchers from the University of California, Irvine, results in the restoration of retinal and visual functions of mice models suffering from inherited retinal disease.
Tags: Health, University of California Irvine


UCI-led researchers receive $3 million NIH grant for 4D Nucleome project

The National Institutes of Health has awarded a team of researchers, led by the University of California, Irvine's Xiangmin Xu, PhD, a five-year, $3 million grant for a project titled, "Single-Cell Analysis of Aging-Associated 4D Nucleome in the Human Hippocampus."
Tags: Health, National Institutes of Health, UCI, University of California Irvine, Xiangmin Xu


New lab-on-a-chip can help study tumor heterogeneity, improve cancer therapies

Electrical engineers, computer scientists and biomedical engineers at the University of California, Irvine have created a new lab-on-a-chip that can help study tumor heterogeneity to reduce resistance to cancer therapies.
Tags: Health, University of California Irvine


Simple sugar in human breast milk can promote myelin repair in multiple sclerosis patients

N-acetylglucosamine, a simple sugar found in human breast milk and sold as an over-the-counter dietary supplement in the United States, promotes myelin repair in mouse models and correlates with myelination levels in multiple sclerosis patients according to a new University of California, Irvine-led study.
Tags: Health, United States, University of California Irvine


Study shows how autoimmune diseases may be targeted using Treg-based cellular therapies

In a new University of California, Irvine-led study, researchers have discovered how regulatory T cells (Treg) are instrumental in limiting the damage caused to the spinal cord in diseases like multiple sclerosis (MS).
Tags: Health, University of California Irvine, Treg


Rising stress and depressive symptoms linked to pandemic-related losses, media consumption

Experiencing multiple stressors triggered by the COVID-19 pandemic – such as unemployment – and COVID-19-related media consumption are directly linked to rising acute stress and depressive symptoms across the U.S., according to a groundbreaking University of California, Irvine study.
Tags: Health, University of California Irvine


Lab-on-a-chip technology detects COVID-19 antibody

A robust, low-cost imaging platform utilizing lab-on-a-chip technology created by University of California, Irvine scientists may be available for rapid coronavirus diagnostic and antibody testing throughout the nation by the end of the year.
Tags: Health, University of California Irvine


Researchers create a design schema for navigation technologies to help people with disabilities

Researchers at the University of Maryland, Baltimore County and the University of California, Irvine have collaborated to create a universal design schema for navigation technologies to better support people with disabilities in getting from place to place.
Tags: Health, University of California Irvine, University of Maryland Baltimore County


UCI researchers develop novel molecule for COVID-19 treatment

When the coronavirus pandemic hit, almost everyone at the University of California, Irvine – and colleges across the nation – had to abandon campus.
Tags: Health, UCI, University of California Irvine


Specifically designed cyclic peptide inhibitor shown to be active against SARS-CoV-2

A new bioRxiv study by a research group from the University of California Irvine shows in vitro activity and non-toxicity of the first-in-class cyclic peptide that inhibits the main protease of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – laying the groundwork for its use in the treatment of coronavirus disease (COVID-19).
Tags: Health, University of California Irvine


Cannabis could be a potentially effective treatment for sickle cell disease pain

Cannabis appears to be a safe and potentially effective treatment for the chronic pain that afflicts people with sickle cell disease, according to a new clinical trial co-led by University of California, Irvine researcher Kalpna Gupta and Dr. Donald Abrams of UC San Francisco. The findings appear in JAMA Network Open.
Tags: Health, University of California Irvine, Kalpna Gupta, Donald Abrams


Researchers discover key signaling pathway in the pathogenesis of Paget's disease

Researchers from the University of California, Irvine, in collaboration with their colleagues from Beijing, China, have gained new insights into the development of poorly understood malignant skin cancers collectively known as Paget's disease.
Tags: Health, Beijing China, University of California Irvine, Paget


Study reveals protein responsible for vulnerability in cancer cells

A new University of California, Irvine-led study reveals a protein responsible for genetic changes resulting in a variety of cancers, may also be the key to more effective, targeted cancer therapy.
Tags: Health, University of California Irvine


Pharmacists involved in cancer care face restricted access to essential PPE items

Oncology pharmacy practitioners around the globe are fighting to provide cancer patients high quality cancer care with increasingly limited and sometimes restricted personal protective equipment supply as well as impaired access to essential anticancer medication, according to University of California, Irvine-led study.
Tags: Health, University of California Irvine


Why coronavirus is spreading faster in Southern California than the rest of the state

As California looks to ease stay-home restrictions imposed to keep COVID-19 in check, infections of the new coronavirus seem to be spreading fastest in the southern third of the state, according to a Bay Area News Group analysis. Of California’s 58 counties, eight of the 10 with the highest rate of new infections are in Southern California. The infection rate is a Gov. Gavin Newsom’s administration is reviewing to allow counties to ease restrictions — to demonstrate “epidemiologic stability,” ...
Tags: Health, News, California, California News, Fresno, Los Angeles, San Francisco, Sport, Ap, Soccer, San Diego, Santa Barbara County, Orange County, Santa Clara, UC Berkeley, Gavin Newsom


Natural approaches along with current therapies could improve colon cancer treatment

Using a modified natural substance along with current approaches could improve colon cancer treatment, according to findings by University of California, Irvine biologists.
Tags: Health, University of California Irvine


Highly purified fish oil therapy could prevent thousands of cardiovascular events

Researchers from the University of California, Irvine have conducted a statistical analysis that predicts more than 70,000 heart attacks, strokes and other adverse cardiovascular events could be prevented each year in the U.S. through the use of a highly purified fish oil therapy.
Tags: Health, University of California Irvine


Researchers show possibility to control cell bioenergetics by changing mitochondria content

Researchers at the University of California, Irvine have shown that they can give cells a short-term boost of energy through mitochondrial transplantation.
Tags: Health, University of California Irvine


Study reveals major changes that occur in mammalian skin cells during wound healing

A team of University of California, Irvine researchers have published the first comprehensive overview of the major changes that occur in mammalian skin cells as they prepare to heal wounds.
Tags: Health, University of California Irvine



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