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Pharma giant J&J just launched a pivotal 60,000-person coronavirus vaccine trial, and we could learn if the shot works by the end of 2020

Steve Parsons-WPA Pool/Getty Images Johnson & Johnson, the world's largest healthcare company, advanced its coronavirus vaccine candidate into the final stage of clinical trials on Wednesday.  J&J will recruit up to 60,000 volunteers from around the world, including in the US, South Africa, Brazil, Argentina, Columbia, and Chile, said Paul Stoffels, the pharma giant's chief scientific officer. Dr. Anthony Fauci, the nation's top infectious-disease expert, estimated that J&J's trial will l...
Tags: Health, Science, US, Trends, Chile, Healthcare, Belgium, Astrazeneca, National Institutes of Health, Pfizer, University of Oxford, Anthony Fauci, Trump, Johnson & Johnson, J J, Fauci


NIH study details self-reported experiences with post-exertional malaise in ME/CFS

One of the major symptoms of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is post-exertional malaise (PEM), the worsening of symptoms after physical or mental activities. Using their own words and experiences, people with ME/CFS described how debilitating PEM can be in a study in Frontiers in Neurology. This is the first publication to come out of the National Institutes of Health's intramural post-infectious ME/CFS study.
Tags: Science, National Institutes of Health, Nih


Negative pressure wound therapy does not cut infection risk in obese women after cesarean

Negative pressure wound therapy (NPWT) does not appear to lower the risk of infection for obese women after cesarean delivery, suggests a study funded by the National Institutes of Health. The treatment involves placing a low-pressure pump over a closed surgical wound to create negative air pressure.
Tags: Science, National Institutes of Health


Pro-Trump NIH Goon to 'Retire' After Being Outed as Prolific Author of Anti-Mask, Anti-Fauci Blog Posts

One of the Trump administration’s flacks at the National Institute of Allergy and Infectious Diseases secretly trashed the agency under the persona “streiff” for the right-wing blog RedState, according to a Monday report by the Daily Beast. He is now planning to “retire.” Read more...
Tags: Health, Politics, Science, National Institutes of Health, Donald Trump, Anthony Fauci, Trump, Misinformation, Pandemic, Coronavirus, Covid 19, Sars Cov 2, Dr Fauci, 4d Chess, Trump NIH Goon


CSUN professor receives $1.4 million grant to study human gut

A Cal State Northridge microbial ecologist has received $1.4 million from the National Institutes of Health to help unravel mysteries involving the distinct bacterial community called the human gut microbiome, the university announced Tuesday, Sept. 15. The four-year grant supports Dr. Gilberto Flores’ research in understanding how one particular bacterium, Akkermansia muciniphila — seen by many health food manufacturers as a potential “good” bacteria to add to their products — promotes health i...
Tags: Science, News, Recommended, Sport, Soccer, Higher Education, Community, National Institutes of Health, Flores, CSUN, Cal State Northridge, Top Stories LADN, Akkermansia, Gilberto Flores


AstraZeneca COVID-19 vaccine trial suspended in US for at least several more days amid concerns over serious complication

A laboratory technicians handles vials as part of filling and packaging tests for the large-scale production and supply of the University of Oxfords COVID-19 vaccine candidate, AZD1222, conducted on a high-performance aseptic vial filling line on September 11, 2020 at the Italian biologics manufacturing facility of multinational corporation Catalent in Anagni, southeast of Rome, during the COVID-19 infection, caused by the novel coronavirus. VINCENZO PINTO/AFP via Getty Images The late-sta...
Tags: Science, News, US, Trends, Bbc, Rome, Britain, South Africa, Astrazeneca, National Institutes of Health, Fda, Nih, Charles Davis, Kaiser Health News, Reuters, US Food and Drug Administration


Substance use disorders linked to COVID-19 susceptibility

A National Institutes of Health-funded study found that people with substance use disorders (SUDs) are more susceptible to COVID-19 and its complications. The research, published today in Molecular Psychiatry, was co-authored by Nora D. Volkow, M.D., director of the National Institute on Drug Abuse (NIDA). The findings suggest that health care providers should closely monitor patients with SUDs and develop action plans to help shield them from infection and severe outcomes.
Tags: Science, National Institutes of Health, National Institute on Drug Abuse NIDA, Nora D Volkow


A scientist won $1.8 million to study how parasitic worms suppress our immune systems with venom to live inside us undetected

A Steinernema carpocapsae nematode — what the worms look like as they spit venom into a host. Adler Dillman/UCR Nearly a quarter of the world's population is infected with parasitic worms called nematodes. Some of these parasites can cause blindness or death. But our bodies' immune systems often have no idea they been invaded because the nematodes release a venom that cloaks their presence. The NIH recently awarded parasitologist Adler Dillman $1.8 million to figure out how these worms go ...
Tags: UK, Science, News, Biology, Animals, Nigeria, US, Trends, Ibd, National Institutes of Health, Parasites, Worms, Nih, Diseases, University of California Riverside, Crohn


We're ignoring one of the most obvious ways to avoid spreading the coronavirus: stop talking so much

Teachers wearing masks attend a meeting at Jean-Jaures elementary school in Cenon near Bordeaux, France on May 11, 2020 amid preparations to re-open primary schools. Mehdi Fedouach/AFP via Getty Images Talking loudly may spread the virus to others better than being quiet. It's possible that this is part of the reason why English speakers have had higher infection rates than the Japanese.  But that doesn't mean we should all go silent.  Talking to others is one of the most important things ...
Tags: Japan, Texas, Science, News, France, Berlin, US, Trends, Mental Health, Public Health, Atlantic, Arizona, Linguistics, National Institutes of Health, University of Pennsylvania, Anthony Fauci


GTEx Consortium releases fresh insights into how DNA differences govern gene expression

Scientists from the Genotype-Tissue Expression (GTEx) project, a National Institutes of Health-funded consortium, have completed a wide-ranging set of studies documenting how small changes in DNA sequence can impact gene expression across more than four dozen tissues in the human body. These studies, released in a set of 15 papers published in Science and other journals, constitute the most comprehensive catalog to date of genetic variations that affect gene expression.
Tags: Science, National Institutes of Health


US lawmakers grilled health officials about COVID-19 vaccines and whether Trump's word about their development can be trusted

US Surgeon General Jerome Adams (L) and National Institutes of Health (NIH) Director Francis Collins (R) bump elbows after testifying before the Senate Health, Education, Labor and Pensions Committee hearing on September 9, 2020 in Washington, DC to discuss vaccines and protecting public health during the coronavirus pandemic. (Photo by Greg Nash / POOL / AFP) (Photo by ) GREG NASH/POOL/AFP via Getty Images Dr. Francis Collins, the director of the National Institutes of Health, and Surgeon...
Tags: Politics, Science, News, Cdc, Senate, US, Trends, Joe Biden, Washington Dc, New York Times, Warren, National Institutes of Health, Vaccine, Donald Trump, Anthony Fauci, Nih


Don't expect a coronavirus vaccine before the election — here's the likely timeline according to doctors, government officials, and analysts

Nurse Kath Olmstead (right) gives volunteer Melissa Harting (left) the Moderna vaccine on July 27, 2020, in Binghamton, New York. AP Photo/Hans Pennink President Trump has suggested that a coronavirus vaccine may become available "right around" the election on November 3. But public-health experts, financial analysts, and US government officials have said that timeline is unrealistic. Most experts think there's little hope of a vaccine being ready before the end of the year. Under the most...
Tags: UK, Science, News, Cdc, Senate, White House, US, Trends, Food And Drug Administration, Astrazeneca, Cbs, National Institutes of Health, Philadelphia, Goldman Sachs, Fda, Npr


Probiotic skin therapy improves eczema in children, NIH study suggests

An experimental treatment for eczema that aims to modify the skin microbiome safely reduced disease severity and increased quality of life for children as young as 3 years of age, a National Institutes of Health study has found. These improvements persisted for up to eight months after treatment stopped, researchers report in Science Translational Medicine.
Tags: Science, National Institutes of Health, Nih


Top drugmakers made a rare joint pledge not to cut corners on the coronavirus vaccine amid fears shots are being rushed before the presidential election

Scientists work on a potential COVID-19 vaccine. Carl Recine/Reuters Leading drug companies have signed a pledge promising to put safety before speed with a coronavirus vaccine. The CEOs of nine companies signed a rare joint pledge promising not to seek regulatory approval before the safety and efficacy of their experimental vaccines are established in Phase 3 clinical trials. They said they expect the pledge to "ensure public confidence in the rigorous scientific and regulatory process by...
Tags: Politics, Science, News, Cdc, White House, US, Trends, Healthcare, News UK, National Institutes of Health, Fda, Associated Press, Pfizer, The New York Times, University Of Arizona, Donald Trump


Leading US drugmakers will sign a pact to produce a safe coronavirus vaccine amid concerns about shots being rushed to market before the presidential election

Scientists work on a potential COVID-19 vaccine. Carl Recine/Reuters Two drug companies at the forefront of the US race to develop a coronavirus vaccine, Moderna and Pfizer, are expected to join a pledge that promises to put safety before speed. In an early draft obtained by the Wall Street Journal, the companies promise to only seek emergency FDA approval after final human trials show "substantial evidence of safety and efficacy." Many public-health experts worry that the Trump administra...
Tags: Science, News, Cdc, White House, US, Trends, National Institutes of Health, Fda, Associated Press, Pfizer, The New York Times, University Of Arizona, Donald Trump, Baltimore, Wall Street Journal, University Of Alabama


Women surgeons earn their cut of NIH funding -- and then some

Women are underrepresented in academic surgery, but women surgeons are earning a disproportionate share of research grants from the National Institutes of Health, a new study has found.
Tags: Science, National Institutes of Health, Nih


NIH study suggests opioid use linked to pregnancy loss, lower chance of conception

Opioid use among women trying to conceive may be associated with a lower chance of pregnancy, suggests a National Institutes of Health study. Moreover, opioid use in early pregnancy may be associated with a greater chance of pregnancy loss.
Tags: Science, National Institutes of Health, Nih


Drugs against alpha-ketoglutarate may combat deadly childhood brain tumor

Every year, 150 to 300 children in the United States are diagnosed with diffuse intrinsic pontine gliomas (DIPGs), aggressive and lethal tumors that grow deep inside the brain, for which there are no cures. In a study funded by the National Institutes of Health, researchers showed that experimental drugs designed to lower the body's natural production of alpha-ketoglutarate extended the lives of mice harboring DIPG tumors by slowing the growth of the cancer cells.
Tags: Science, United States, National Institutes of Health


NIH-supported scientists demonstrate how genetic variations cause eczema

New research supported by the National Institutes of Health delineates how two relatively common variations in a gene called KIF3A are responsible for an impaired skin barrier that allows increased water loss from the skin, promoting the development of atopic dermatitis, commonly known as eczema. This finding could lead to genetic tests that empower parents and physicians to take steps to potentially protect vulnerable infants from developing atopic dermatitis and additional allergic diseases.
Tags: Science, National Institutes of Health, Nih


NIH researchers discover new set of channels connecting malaria parasite and blood cells

Researchers at the National Institutes of Health and other institutions have discovered another set of pore-like holes, or channels, traversing the membrane-bound sac that encloses the deadliest malaria parasite as it infects red blood cells. The channels enable the transport of lipids--fat-like molecules--between the blood cell and parasite, Plasmodium falciparum. The parasite draws lipids from the cell to sustain its growth and may also secrete other types of lipids to hijack cell functions to...
Tags: Science, National Institutes of Health, Nih


Experimental COVID-19 vaccine protects upper and lower airways in nonhuman primates

Two doses of an experimental vaccine to prevent coronavirus disease 2019 (COVID-19) induced robust immune responses and rapidly controlled the coronavirus in the upper and lower airways of rhesus macaques exposed to SARS-CoV-2, report scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. SARS-CoV-2 is the virus that causes COVID-19.
Tags: Science, National Institutes of Health


Kidney transplantation between people with HIV is safe, NIH study finds

Kidney transplantation from deceased donors with HIV to people living with both HIV and end-stage kidney disease is feasible and safe, investigators supported by the National Institutes of Health have found. Their study demonstrates that the pool of available kidneys for people with HIV can be expanded by including donors with HIV, making more kidneys available for all who are awaiting a transplant.
Tags: Science, National Institutes of Health, Nih


NIH leadership details unprecedented effort to ramp up testing technologies for COVID-19

In a paper in NEJM, scientific leaders from the National Institutes of Health set forth a framework to increase significantly the number, quality and type of daily tests for detecting SARS-CoV-2, the virus that causes COVID-19, and help reduce inequities for underserved populations that have been disproportionally affected by the disease. The authors describe the current testing landscape and explain the urgent need for nationwide deployment of low-complexity, point-of-care molecular diagnostics...
Tags: Science, National Institutes of Health, Nih, NEJM


UK coronavirus vaccine prompts immune response in early test

By MARIA CHENG LONDON  — Scientists at Oxford University say their experimental coronavirus vaccine has been shown in an early trial to prompt a protective immune response in hundreds of people who got the shot. British researchers first began testing the vaccine in April in about 1,000 people, half of whom got the experimental vaccine. Such early trials are designed to evaluate safety and see what kind of immune response was provoked, but can’t tell if the vaccine truly protects. In research pu...
Tags: Health, Business, UK, Science, London, News, China, Uncategorized, Sport, World news, Britain, Soccer, South Africa, Oxford, Brazil, Astrazeneca


NFL outperforms other blood tests to predict and diagnose traumatic brain injury

A study from the National Institutes of Health showed that neurofilament light chain (NfL) delivered superior diagnostic and prognostic performance as a blood biomarker for mild, moderate, and severe traumatic brain injury (TBI) when compared to blood proteins glial fibrillary acidic protein, tau, and ubiquitin c-terminal hydrolase-L1. The research was conducted by scientists at the NIH Clinical Center, Bethesda, Maryland, and published in the July 8, 2020, online issue of Neurology.
Tags: Science, NFL, National Institutes of Health, TBI, NIH Clinical Center Bethesda Maryland


Blood-based biomarker can detect, predict severity of traumatic brain injury

A study from the National Institutes of Health confirms that neurofilament light chain as a blood biomarker can detect brain injury and predict recovery in multiple groups, including professional hockey players with acute or chronic concussions and clinic-based patients with mild, moderate, or severe traumatic brain injury.
Tags: Science, National Institutes of Health


Outdoor light linked with teens' sleep and mental health

Research shows that adolescents who live in areas that have high levels of artificial light at night tend to get less sleep and are more likely to have a mood disorder relative to teens who live in areas with low levels of night-time light. The research was funded by the National Institute of Mental Health (NIMH), part of the National Institutes of Health, and is published in JAMA Psychiatry.
Tags: Science, National Institutes of Health, National Institute of Mental Health NIMH


Iodine exposure in the NICU may lead to decrease in thyroid function, NIH study suggests

Exposure to iodine used for medical procedures in a neonatal intensive care unit (NICU) may increase an infant's risk for congenital hypothyroidism (loss of thyroid function), suggests a study by researchers at the National Institutes of Health and other institutions.
Tags: Science, National Institutes of Health, Nih, NICU


NIH ACTIV working group weighs human challenge studies for SARS-CoV-2 vaccine development

In a Perspective for the New England Journal of Medicine, members of the National Institutes of Health's Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) Vaccines Working Group assess practical considerations and prerequisites for using controlled human infection models (CHIMs), which can be used for human challenge studies, to support SARS-CoV-2 vaccine development.
Tags: Science, National Institutes of Health, Nih, New England Journal of Medicine, Vaccines Working Group


NIH study finds out why some words may be more memorable than others

In a recent study of epilepsy patients and healthy volunteers, National Institutes of Health researchers found that our brains may withdraw some common words, like "pig," "tank," and "door," much more often than others, including "cat," "street," and "stair." By combining memory tests, brain wave recordings, and surveys of billions of words published in books, news articles and internet encyclopedia pages, the researchers not only showed how our brains may recall words but also memories of our p...
Tags: Science, National Institutes of Health, Nih



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