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Arthritis drug is no better than standard care in improving severe COVID-19 outcomes, shows new trial

Adding the arthritis drug tocilizumab to standard care for patients in hospital with severe or critical covid-19 is no better than standard care alone in improving clinical outcomes at 15 days, finds a new trial published by The BMJ today.
Tags: Health, Bmj


New trial finds arthritis drug no better than standard care for severe covid-19

Adding the arthritis drug tocilizumab to standard care for patients in hospital with severe or critical covid-19 is no better than standard care alone in improving clinical outcomes at 15 days, finds a new trial published by The BMJ today.
Tags: Science, Bmj


A Natural Intellectual Property Experiment Proves What Is Necessary May Not Be Sufficient

On December 1, 2020, Dr. Sott Atlas resigned his position as “special advisor [on the coronavirus] to the president of the United States.” Many of us breathed a sigh of relief, if through our masks. After all, my Stanford colleagues had voted for a faculty senate resolution, that condemned this Stanford-affiliated man’s “disdain for established medical knowledge.” To take but one example I’ll return to below, Atlas had tweeted “Masks work? NO,” citing Oxford Professor Carl Heneghan. What Atlas i...
Tags: Law, Stanford, Atlas, United States, Oxford, Pfizer, Bmj, Heneghan, Legal Publishing, Moderna, Scott Atlas, Altas, Tom Jefferson, COVID, Carl Heneghan, Sott Atlas


UK government plans to expand the innova lateral flow test, warn experts

UK government plans to widen the roll out of the Innova lateral flow test without supporting evidence risks serious harm, warn experts in The BMJ today.
Tags: Health, UK, Bmj, Innova


UK government must urgently rethink lateral flow test roll out, warn experts

UK government plans to widen the roll out of the Innova lateral flow test without supporting evidence risks serious harm, warn experts in The BMJ today.
Tags: UK, Science, Bmj, Innova


Coronavirus: BMJ urges NYT to correct vaccine 'mixing' article

The medical journal's editor says UK guidelines don't recommend giving different coronavirus jabs.
Tags: UK, News, Bmj


How Do Vaccines (Including the COVID-19 Vaccines) Work?: Watch Animated Introductions

https://www.youtube.com/watch?v=rb7TVW77ZCs The other day, I found myself reading about what life is like in countries that have successfully minimized the pandemic: worry free holidays, meeting friends and family without the danger of infection, a general air of normalcy thanks to a combination of rigorous public health efforts and public cooperation. I live in the U.S., where the political party currently in power (and desperate to keep it) convinced millions of my fellow citizens that...
Tags: Health, Google, Science, College, America, United States, Current Affairs, Who, Philadelphia, Pbs, Bmj, Johns Hopkins, Facebook Twitter, Josh Jones, Durham NC Follow, Katherine O'Brien


Liverpool is attempting mass COVID-19 testing during the UK's lockdown — but the reaction to the program is mixed

Liverpool is undertaking a mass coronavirus testing pilot, with residents having access to lateral flow tests that are able to determine if someone has coronavirus in under an hour. Peter Byrne/Getty Images Liverpool's mass COVID-19 testing program, a pilot in Prime Minister Boris Johnson's "Operation Moonshot vision," is dividing public health officials and politicians, according to The Washington Post. The Post reported that as of November 3, Liverpool's weekly rate of COVID-19 tests was...
Tags: Post, Politics, UK, England, Science, Trends, Bbc, NHS, Liverpool, Boris Johnson, University of Bristol, Public Health England, The Washington Post, Bmj, Pcr, Cabinet Office


Vaccine trials didn't monitor one variable: volunteers' behavior. 'Masks and social distancing were left up to us,' a participant said.

People wear face masks at the Union Square Greenmarket on September 19, 2020, in New York City. Noam Galai/Getty Images In their COVID-19 vaccine trials, Pfizer and Moderna didn't monitor participants' social interactions, risk-taking, or exposure after they were injected with a vaccine or placebo.  Volunteers who suspected they'd gotten the vaccine may have been inclined to engage in riskier behavior. Public-health experts say the risk of getting COVID-19 was relatively low for most trial...
Tags: Science, News, US, Trends, Atlanta, Turkey, Philadelphia, Pfizer, Bmj, Hamilton, Children s Hospital, Paul Offit, Abbot Kinney Boulevard, Medscape, Moderna, University of Maryland School of Pharmacy


Spinal or epidural anesthesia linked with high survival rate in leg artery bypass surgery

A new study published in The BMJ shows that people who had surgery to improve blood flow in their legs under spinal or epidural anesthesia were less likely to die than those who were given general anesthesia.
Tags: Health, Bmj


Spinal/epidural anesthesia associated with increased survival in leg artery bypass surgery

A new study published in The BMJ shows that people who had surgery to improve blood flow in their legs under spinal or epidural anesthesia were less likely to die than those who were given general anesthesia.
Tags: Science, Bmj


The WHO will not recommend remdesivir for COVID-19 patients, since it doesn't seem to boost their chances of survival

A vial of remdesivir as seen during a news conference at the University Hospital Eppendorf in Hamburg, Germany, April 8, 2020. Ulrich Perrey/Reuters The FDA approved remdesivir as a treatment for severe COVID-19 cases last month, after granting emergency authorization in May. But on Thursday, the World Health Organization announced it will not recommend the drug's use for COVID-19 patients. "There is currently no evidence that it improves survival or the need for ventilation," the organiza...
Tags: Science, News, International, Trends, Who, World Health Organization, Fda, The New York Times, Bmj, Reuters, Brussels Belgium, University of Birmingham, Gilead Sciences, Houston Texas, Hamburg Germany, Ridley


WHO Guideline Development Group advises against use of remdesivir for covid-19

The antiviral drug remdesivir is not suggested for patients admitted to hospital with covid-19, regardless of how severely ill they are, because there is currently no evidence that it improves survival or the need for ventilation, say a WHO Guideline Development Group (GDG) panel of international experts in The BMJ today.
Tags: Science, Bmj, WHO Guideline Development Group


Politicians and governments are suppressing science, argues The BMJ

Politicians and governments are suppressing science, and when good science is suppressed, people die, argues a senior editor at The BMJ today.
Tags: Science, Bmj


Machine learning shows similar performance to traditional risk prediction models

Some claim that machine learning technology has the potential to transform healthcare systems, but a study published by The BMJ finds that machine learning models have similar performance to traditional statistical models and share similar uncertainty in making risk predictions for individual patients.
Tags: Science, Bmj


Covid-19 vaccine trials cannot tell us if they will save lives

Vaccines are being hailed as the solution to the covid-19 pandemic, but the vaccine trials currently underway are not designed to tell us if they will save lives, reports Peter Doshi, Associate Editor at The BMJ today.
Tags: Science, Bmj, Peter Doshi


New tool predicts risks of hospital admission and death from Covid-19

A new risk tool, developed by UK researchers to predict a person's risk of being admitted to hospital and dying from Covid-19 has been published by The BMJ today.
Tags: UK, Science, Bmj


A UK model suggests school closures could lead to more deaths after lockdowns lift — but experts are wary of the prediction

A woman disinfects a school hallway. Getty A new peer-reviewed report suggests that closing UK schools may have led to more COVID-19 deaths than if schools had stayed open. But the model is based on an "unrealistic" scenario, experts say. It assumes that lockdown measures are completely lifted after three months, before a vaccine is available. Other studies show that school closures lower coronavirus transmission — potentially resulting in fewer deaths. Visit Business Insider's homepage fo...
Tags: School, UK, Science, News, Education, Germany, Israel, US, Trends, Nature, Shanghai, Ferguson, Graham, Getty, University of Warwick, Anthony Fauci


Neocis, the maker of dental surgery robots, roots out another $72 million

Since the robotic dental surgery assistant Yomi first came on the market in 2019 more than 2,700 patients have stared up at its plastic sheathed metal arms, and now the company behind it, Neocis, has raised $72 million to bring it into more dentists’ offices. The money came from new investors DFJ Growth and Vivo Capital, with existing investors Mithril Capital Management, Norwest Venture Partners, Section 32, and the godfather of robotic surgery Fred Moll all participating in the new funding rou...
Tags: TC, UK, Tech, West Virginia University, Houston, Bmj, Dfj, Boston University, U S Food and Drug Administration, Yomi, Vivo Capital, Fred Moll, Neocis, Mike Liang Naila Dhanani, Oscar Olavarria, Alon Mozes Neocis


Exercise intensity not linked to mortality risk in older adults, finds trial

Exercise intensity appears to make no difference to risk of mortality among older adults, suggests a randomised controlled trial from Norway published by The BMJ today.
Tags: Science, Norway, Bmj


Is it time to reframe the assisted dying debate?

Several articles published by The BMJ today explore the debate around assisted dying, in which, subject to safeguards, terminally ill people who are near to death, suffering, and of sound mind, could ask for drugs that they would take to end their lives.
Tags: Science, Bmj


With proven dangers to prolonged wearing of cloth masks, what is a parent to do?

I am well aware that for some people the science on masks is over, they've heard what they want to hear, that masks may provide some utility in mitigating viral spread, and that's that.....the book is closed. True students of science of course know that science is a process, and that things can change as newer and/or better evidence comes out.  Changes can be sublte, evolving over time, or they can be dramatic.  New studies are done, in science the gold standard is radomized trials, with some...
Tags: Travel, Bmj, University of Toronto, Ontario, Cbc, Furness, British Medical Journal BMJ, Gordie Canuk, COVID, Colin Furness


Systematic efforts and clear structure are crucial for person-centered care

Systematic efforts and a clear structure are decisive factors in the transition to person-centred health care. A University of Gothenburg study, published in the scientific journal BMJ, reflects what is now a decade of experience and research in the field.
Tags: Health, Bmj, University of Gothenburg


Systematic approach crucial for person-centred care

Systematic efforts and a clear structure are decisive factors in the transition to person-centred health care. A University of Gothenburg study, published in the scientific journal BMJ, reflects what is now a decade of experience and research in the field.
Tags: Science, Bmj, University of Gothenburg


New research sheds light on the risks of COVID-19 for pregnant women and their babies

New research findings published today in the BMJ helps to shed light on the risks of COVID-19 for pregnant women and their babies.
Tags: Health, Bmj


Shifting public health messaging about face coverings could improve uptake

Encouraging the public to see face masks as a social practice, which they can use to express their cultural background or their personality, could encourage more people to use them regularly, say researchers writing in The BMJ today.
Tags: Science, Bmj


Premature delivery linked to heightened risk of early death for mothers

Preterm and early term delivery are independent risk factors for premature death in women up to 40 years later, finds a study from Sweden published by The BMJ today.
Tags: Science, Sweden, Bmj


Experts make weak recommendation for remdesivir in severe COVID-19

In The BMJ today, a panel of international experts make a weak recommendation for the use of remdesivir in patients with severe covid-19, and strongly support continued enrolment of patients into ongoing clinical trials of remdesivir.
Tags: Science, Bmj


Diets high in protein, particularly plant protein, linked to lower risk of death

Diets high in protein, particularly plant protein, are associated with a lower risk of death from any cause, finds an analysis of the latest evidence published by The BMJ today.
Tags: Science, Bmj


Why are patient and public voices absent in COVID-19 policy-making?

Patient and public voices were "regrettably" absent in the early stages of the COVID-19 pandemic, but must now move centre stage, argue experts in The BMJ today.
Tags: Science, Bmj, COVID