Posts filtered by tags: Children's Hospital[x]


 

Scotland's vaccine rollout suggests delaying the 2nd COVID-19 shot is a bad idea

A frontline healthcare worker receives a Moderna COVID-19 vaccination at the Park County Health Departments storefront clinic on January 5, 2021 in Livingston, Montana. Photo by William Campbell/Getty Images The UK strategy to delay the second coronavirus vaccine dose for up to 12 weeks carries real risk. New data from Scotland showed protection against hospitalization peaking after five weeks — and then declining. Vaccine developers and public-health experts told Insider it's a mistake to...
Tags: Health, UK, Science, News, Obama, Scotland, Israel, Trends, Healthcare, Astrazeneca, Philadelphia, Pfizer, Children s Hospital, Patel, Paul Offit, Livingston Montana


CHOP experts describe types of rashes associated with MIS-C

In a study published in Open Forum Infectious Diseases, researchers at Children's Hospital of Philadelphia (CHOP) describe the array of rashes seen in MIS-C patients at their hospital through late July 2020, providing photos and information that could help doctors diagnose future cases.
Tags: Science, Philadelphia, Children s Hospital


The first dose of the Pfizer vaccine is 85% effective, Israeli study finds

Sheba's research suggests an 85% reduction in symptomatic COVID-19 within 15 to 28 days. Dado Ruvic/Reuters The first dose of Pfizer and BioNTech's coronavirus vaccine is 85% effective, Reuters reported. The UK government has already prioritized the first dose scheme over the two-shot scheme. The European Medicines Agency and the FDA are against delaying the second vaccine dose, however. Visit the Business section of Insider for more stories. The first dose of Pfizer and BioNTech's cor...
Tags: UK, Israel, US, Trends, Philadelphia, Fda, Pfizer, Reuters, European Medicines Agency, Children s Hospital, US Food and Drug Administration FDA, Sheba, European Medicines Agency EMA, Gaston De Serres, Paul Offit, Reuters Two


A potentially safer, more effective gene therapy vector for blood disorders

Researchers at Children's Hospital of Philadelphia (CHOP) have developed a gene therapy vector for blood disorders like sickle cell disease and beta-thalassemia that is potentially safer and more effective than those currently used in gene therapy trials for those conditions. The vector, an engineered vehicle for delivering functional copies of the hemoglobin gene to correct a genetic abnormality, leads to the production of more hemoglobin with a lower dose, minimizing the risk of toxic side eff...
Tags: Science, Philadelphia, Children s Hospital


Boston Children’s Hospital Employees Announce Engagement While Getting Vaccinated Together

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Tags: Boston, Massachusetts, Cbs, Olivia, Boston Children s Hospital, Children s Hospital, Around the Nation, Boston Children 's Hospital Employees


Are Experts Underselling the Effectiveness of Covid-19 Vaccines?

David Leonhardt won a Pulitzer Prize for commentary in 2011. This week in a New York Times newsletter, he argues that early in the pandemic experts around the world mistakenly discouraged mask use because of "a concern that people would rush to buy high-grade medical masks, leaving too few for doctors and nurses. The experts were also [at the time] unsure how much ordinary masks would help." But are they now spreading a similarly misguided pessimism about vaccines? Right now, public discussio...
Tags: Tech, New York Times, Philadelphia, Pfizer, Peter Hotez, Baylor College of Medicine, Children s Hospital, Paul Offit, David Leonhardt, Moderna, Vaccine Education Center


Kamala Harris was just sworn in as the first female vice president in US history. Here are 35 of the most powerful women in 2021.

Kamala Harris, Jill Biden, and Shonda Rhimes. Tasos Katopodis/JIM WATSON/AFP/George Pimentel/Getty Images First ladies, political figures, and prominent businesswomen hold great power in the US. Kamala Harris was sworn in as the first female vice president of the United States. Queen Elizabeth II, the longest-reigning monarch of the United Kingdom, has served for over 65 years. Visit Business Insider's homepage for more stories. From the boardroom to Hollywood and the floor of the House of...
Tags: Strategy, Features, Women And Leadership, Women's History Month, Feminism, Women, CDU


New drug reduces tumor volume and pain in patients with neurofibromatosis type 1

Based on preclinical studies of an investigational drug to treat peripheral nerve tumors, researchers at Children's Hospital of Philadelphia (CHOP) as part of the Neurofibromatosis Clinical Trials Consortium have shown that the drug, cabozantinib, reduces tumor volume and pain in patients with the genetic disorder neurofibromatosis type 1 (NF1).
Tags: Health, Philadelphia, Children s Hospital, Neurofibromatosis Clinical Trials Consortium


CHOP researchers Find NTRK fusions more common than expected in pediatric tumors

Researchers from Children's Hospital of Philadelphia (CHOP) have found that NTRK fusions are more common in pediatric tumors and also involve a wider range of tumors than adult cancers, information that could help prioritize screening for NTRK fusions in pediatric cancer patients who might benefit from treatment with TRK inhibitors.
Tags: Science, Philadelphia, Children s Hospital


35 of the most powerful women in 2021

Kamala Harris, Jill Biden, and Shonda Rhimes. Tasos Katopodis/JIM WATSON/AFP/George Pimentel/Getty Images From first ladies of the United States to prominent businesswomen and leading figures in the entertainment industry, these women hold great power. On January 20, Senator Kamala Harris will be sworn in as the first female and first Black and South Asian vice president of the United States. Queen Elizabeth II, one of the best-known female leaders in the world and the longest-reigning mon...
Tags: Strategy, Features, Women And Leadership, Women's History Month, Feminism, Women, CDU


Study demonstrates efficacy of new treatment for neurofibromatosis type 1-related tumors

Based on preclinical studies of an investigational drug to treat peripheral nerve tumors, researchers at Children's Hospital of Philadelphia (CHOP) as part of the Neurofibromatosis Clinical Trials Consortium have shown that the drug, cabozantinib, reduces tumor volume and pain in patients with the genetic disorder neurofibromatosis type 1 (NF1). The results of the Phase 2 clinical trial, co-chaired by Michael J. Fisher, MD at CHOP, were published recently in Nature Medicine.
Tags: Science, Philadelphia, Children s Hospital, Neurofibromatosis Clinical Trials Consortium, Michael J Fisher


Researchers identify nanoparticles that could deliver therapeutic mRNA before birth

Researchers at Children's Hospital of Philadelphia and the School of Engineering and Applied Science at the University of Pennsylvania have identified ionizable lipid nanoparticles that could be used to deliver mRNA as part of fetal therapy. The proof-of-concept study, published today in Science Advances, engineered and screened a number of lipid nanoparticle formulations for targeting mouse fetal organs and has laid the groundwork for testing potential therapies to treat genetic diseases before...
Tags: Science, Philadelphia, University of Pennsylvania, Children s Hospital, School of Engineering


Apps and web portals are streamlining vaccine rollout, but the digital strategies could leave vulnerable populations behind, experts warn

A healthcare worker administers a COVID-19 vaccine to an elderly Palestinian man at the Clalit Health Services in the Palestinian neighbourhood of Beit Hanina, in the Israeli-annexed east Jerusalem, on January 7, 2021. Ahmad Gharabli/ AFP/ Getty Images Health systems are starting to give Americans aged 65 and older vaccine access, and some are using smartphone apps and online programs to streamline the process.  But some older people without smartphones or computers reportedly had difficul...
Tags: Florida, Usa, News, Colorado, US, Haven, Jerusalem, America, Trends, Walmart, Hospitals, Tennessee, Healthcare, Food And Drug Administration, Philadelphia, Older people


US Allows Pfizer’s Emergency COVID-19 Vaccine

WASHINGTON (AP) — The U.S. gave the final go-ahead Friday to the nation’s first COVID-19 vaccine, marking what could be the beginning of the end of an outbreak that has killed nearly 300,000 Americans. Shots for health workers and nursing home residents are expected to begin in the coming days after the Food and Drug Administration authorized an emergency rollout of what promises to be a strongly protective vaccine from Pfizer Inc. and its German partner BioNTech. Initial doses are scarce a...
Tags: Europe, News, Washington, China, Russia, US, Ap, Britain, Food And Drug Administration, Philadelphia, Fda, Pfizer, Donald Trump, Trump, The Associated Press, Johnson Johnson


Researchers find elevated biomarker for blood vessel damage in children with SARS-CoV-2

Researchers at Children's Hospital of Philadelphia have found elevated levels of a biomarker related to blood vessel damage in children with SARS-CoV-2 infection, even if the children had minimal or no symptoms of COVID-19.
Tags: Health, Philadelphia, Children s Hospital


Elevated biomarker for blood vessel damage found in all children with SARS-CoV-2

Researchers at Children's Hospital of Philadelphia (CHOP) have found elevated levels of a biomarker related to blood vessel damage in children with SARS-CoV-2 infection, even if the children had minimal or no symptoms of COVID-19. They also found that a high proportion of children with SARS-CoV-2 infection met clinical and diagnostic criteria for thrombotic microangiopathy (TMA).
Tags: Science, Philadelphia, Children s Hospital, COVID


Study finds no significant change in preterm or stillbirth rates during COVID-19 pandemic

Despite early reports suggesting a decline in preterm births during the COVID-19 pandemic period, an analysis by researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania has found no change in preterm births or stillbirths at two Philadelphia hospitals in the first four months of the pandemic.
Tags: Health, Philadelphia, University of Pennsylvania, Perelman School of Medicine, Children s Hospital


What it feels like to get an mRNA coronavirus vaccine

By Andrea Kane | CNN As the United States inches closer to authorizing a Covid-19 vaccine many people may now let themselves start wondering what it will feel like to get it. Is it going to be like the flu vaccine? Will it be more painful? And what about side-effects? The two front-runners for getting an emergency use authorization from the US Food and Drug Administration — Pfizer/BioNTech and Moderna — use new mRNA technology. No US-licensed vaccine has ever used it, although researchers have ...
Tags: Facebook, Mark Zuckerberg, News, California, Boston, US, Sport, Cnn, Soccer, United States, Philadelphia, Fda, Pfizer, Anthony Fauci, Nih, Rudy Giuliani


Study finds no change in preterm birth or stillbirth in Philadelphia during pandemic

Despite early reports suggesting a decline in preterm births during the COVID-19 pandemic period, an analysis by researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania has found no change in preterm births or stillbirths at two Philadelphia hospitals in the first four months of the pandemic. The findings, published today in JAMA, resulted from the examination of an ongoing, racially-diverse pregnancy cohort that assesses bo...
Tags: Science, Philadelphia, University of Pennsylvania, Perelman School of Medicine, Children s Hospital


No One Who Got Moderna's Vaccine In Trial Developed Severe COVID-19

An anonymous reader quotes a report from Science Magazine: Continuing the spate of stunning news about COVID-19 vaccines, the biotech company Moderna announced the final results of the 30,000-person efficacy trial for its candidate in a press release today: Only 11 people who received two doses of the vaccine developed COVID-19 symptoms after being infected with the pandemic coronavirus, versus 185 symptomatic cases in a placebo group. That is an efficacy of 94.1%, the company says, far above wh...
Tags: Tech, Philadelphia, U S Food and Drug Administration FDA, European Medicines Agency, Children s Hospital, EUA, Paul Offit, Moderna


Scientists are aiming to launch a nationwide trial 'as soon as possible' to find out if the top coronavirus vaccines can stop the virus from spreading

A 16-year-old participates in Pfizer's clinical trial to test its coronavirus vaccine candidate. Cincinnati Children’s Hospital Massive studies have shown that two leading coronavirus vaccines are highly effective at preventing people from getting sick with COVID-19, the disease caused by the coronavirus. Top researchers are already pitching plans for additional studies, Business Insider has learned. This research aims to answer a critical question: can these experimental shots also pr...
Tags: Science, US, Trends, Healthcare, Philadelphia, University of Pennsylvania, Pfizer, University Of North Carolina, Cohen, Corey, UNC, Children s Hospital, National Cancer Institute, Paul Offit, NCI, Lowy


Vaccine trials didn't monitor one variable: volunteers' behavior. 'Masks and social distancing were left up to us,' a participant said.

People wear face masks at the Union Square Greenmarket on September 19, 2020, in New York City. Noam Galai/Getty Images In their COVID-19 vaccine trials, Pfizer and Moderna didn't monitor participants' social interactions, risk-taking, or exposure after they were injected with a vaccine or placebo.  Volunteers who suspected they'd gotten the vaccine may have been inclined to engage in riskier behavior. Public-health experts say the risk of getting COVID-19 was relatively low for most trial...
Tags: Science, News, US, Trends, Atlanta, Turkey, Philadelphia, Pfizer, Bmj, Hamilton, Children s Hospital, Paul Offit, Abbot Kinney Boulevard, Medscape, Moderna, University of Maryland School of Pharmacy


INSIDER Poll: Nearly one in five respondents cancelled their Thanksgiving travel plans due to COVID-19

Travellers check in at Washington's Dulles International Airport in Dulles, Virginia, on November 24, 2020. Experts are worried that traveling for the holiday season will result in a new COVID-19 spike. NICHOLAS KAMM/AFP via Getty Images) According to Insider polling from November 20 to 21, nearly one in five respondents canceled their pre-made Thanksgiving travels plans as a result of the ongoing COVID-19 pandemic. Additionally, nearly 19% of respondents reported Thanksgiving travel p...
Tags: Cdc, Washington, US, Trends, Ap, United States, Philadelphia, Associated Press, Transportation Security Administration, Center for Disease Control, Children s Hospital, Dulles Virginia, Dulles International Airport, David Rubín, Coronavirus Research Center, Madison Hall


Thanksgiving could be make-or-break for US coronavirus response

By MICHAEL RUBINKAM | Associated Press In Pennsylvania, if you’re having friends over to socialize, you’re supposed to wear a mask — and so are your friends. That’s the rule, but Barb Chestnut has no intention of following it. “No one is going to tell me what I can or not do in my own home” said Chestnut, 60, of Shippensburg. “They do not pay my bills and they are not going to tell me what to do.” As governors and mayors grapple with an out-of-control pandemic, they are ratcheting up mask mandat...
Tags: Facebook, Utah, News, California, Kentucky, Oregon, New York City, US, Los Angeles, Sport, Soccer, Pennsylvania, Gop, Philadelphia, Associated Press, Andrew Cuomo


CHOP researchers reverse severe lymphatic disorder in patient with Noonan syndrome

Researchers at Children's Hospital of Philadelphia (CHOP) have resolved a severe lymphatic disorder in a girl with Noonan Syndrome that had led to upper gastrointestinal bleeding, fluid collection around the lungs, and numerous surgeries that had been unable to resolve her symptoms. By identifying a genetic mutation along a pathway related to lymphatic vessel development and function, the research team was able to target the pathway using an existing drug they had used in a previous case to remo...
Tags: Science, Philadelphia, Children s Hospital


AI can help recognize individuals with congenital adrenal hyperplasia based on facial images

Researchers at the VISTA Center (Vision, Image, Speech and Text Analytics) at the USC Viterbi Information Sciences Institutealong with scholars at the Keck School of Medicine of USC and Children's Hospital Los Angeles have discovered strong correlations between facial morphology and congenital adrenal hyperplasia (CAH), a life-threatening genetic condition of the adrenal glands and one of the most common forms of adrenal insufficiency in children.
Tags: Health, Los Angeles, Children s Hospital, Keck School of Medicine of USC, USC Viterbi Information Sciences Institutealong


Moderna's coronavirus vaccine can cause severe fatigue and aches and pains. Two top vaccine experts told us why they think you'll still take it.

Moderna COVID vaccine trial volunteer receives injection that could be the vaccine. Data's been released that provides an indication of possible side effects. Hans Pennink/AP Photo Moderna said its vaccine has side effects like muscle aches and fatigue. Experts say that if the vaccine prevents COVID-19, then mild or moderate side effects won't impact vaccine uptake. The experts said they're waiting on the full data before recommending Moderna's shot.  Visit Business Insider's homepage ...
Tags: Trends, Joe Biden, Philadelphia, Fda, GlaxoSmithKline, Pfizer, US Food and Drug Administration, GSK, Fitzpatrick, Children s Hospital, Goodman, Emergency Department, Paul Offit, Lisa Fitzpatrick, Moderna, Offit


‘The Elf on the Shelf’ all-new drive-thru holiday attraction prepares for Pomona debut

On top of all of the other chaos happening in 2020, Santa Claus is in need of a little extra Christmas spirit this year to get his sleigh off the ground. Here’s the situation: Santa crash-landed at the Fairplex in Pomona and is sending his elf scouts to help conjure up some seasonal cheer within The Elf on the Shelf’s Magical Holiday Journey drive-thru experience. The event runs from 5-9:30 p.m. Tuesdays-Sundays (and select Mondays) Nov. 12-Jan. 3 (with some preview dates and times available Nov...
Tags: Holidays, Christmas, Disney, Los Angeles, Sport, Things To Do, Soccer, Broadway, Santa Claus, Santa, Southern California, Pomona, Lasalle, Cirque Du Soleil, Children s Hospital, Fairplex


Study suggests a role for the hypothalamus in genetic susceptibility to IBD

Using sophisticated 3D genomic mapping and integrating with public data resulting from genome-wide association studies, researchers at Children's Hospital of Philadelphia have found significant genetic correlations between inflammatory bowel disease and stress and depression.
Tags: Health, Ibd, Philadelphia, Children s Hospital


CHOP genomic study reveals role for hypothalamus in inflammatory bowel disease

Using sophisticated 3D genomic mapping and integrating with public data resulting from genome-wide association studies (GWAS), researchers at Children's Hospital of Philadelphia (CHOP) have found significant genetic correlations between inflammatory bowel disease (IBD) and stress and depression.
Tags: Science, Ibd, Philadelphia, Children s Hospital, GWAS