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Bio Roundup: Nationwide’s Rise, a Surgeon’s Quest, CRISPR USA & More

Persistence and perseverance were the themes of two of our top stories this week.First there’s the story of Nationwide Children’s Hospital. The Columbus, Ohio, hospital chose to invest in gene therapy when the field was in its darkest days. After some ups and downs, the team it put in place helped advance some of the most promising gene therapies currently in human testing—and put Nationwide in the national spotlight as one of those treatments nears FDA approval.Then there’s Suzanne Ildstad. A ...
Tags: Boston blog main, Boston top stories, Boulder/Denver blog main, Boulder/Denver top stories, Detroit blog main, Detroit top stories, Indiana blog main, Indiana top stories, National, National blog main, National top stories, New York blog main, New York top stories, Raleigh-Durham blog main, Raleigh-Durham top stories, San Diego blog main


Humatics, Vecna Partner to Improve Navigation of Self-Driving Robots

Humatics, a Waltham, MA-based startup developing microlocation technology for use in robots and autonomous vehicles, has a new partnership underway with Boston-based Vecna Robotics.Financial terms of the collaboration were not disclosed, but Humatics co-founder and CEO David Mindell describes the relationship as a joint marketing partnership. “We bring customers to them and vice-versa,” he says.Humatics was spun out of MIT in 2015 to develop a spatial intelligence platform revolving around loca...
Tags: Startups, Entrepreneurship, Boston, Trends, Tech, Mit, Vc, Software, Innovation, Venture Capital, Detroit, Navigation, Industrial Robots, Waltham, Eckhart, David Mindell


$100M For Talaris Gives Surgeon a Shot to Reinvent Organ Transplants

When Novartis dissolved its gene and cell therapy unit a few years ago, a bunch of projects the Swiss pharma giant had incubated were tossed aside. One of them was the work of surgeon Suzanne Ildstad, who has spent decades trying to develop a new way to improve the health outcomes of patients who need organ transplants.That work has just been salvaged. If it plays out as Ildstad hopes, her company might not only help transform treatment for kidney failure patients—but possibly, for people suffe...
Tags: Deals, Startups, Boston, Trends, Vc, National Institutes of Health, Novartis, Stem Cell, Stanford University, Life Sciences, Blackstone Group, Louisville Ky, National blog main, New York blog main, New York top stories, Seattle blog main


MedHealth Summit Brings Together Cross-Border Innovators and Experts

As the healthcare industry continues to undergo technology-driven changes, innovators in digital health and medical devices will gather in Detroit Thursday for a daylong conference.The MedHealth Summit, held at Ford Field’s Hall of Legends, will bring together experts and entrepreneurs from across Southeast Michigan and Southwest Ontario for a day of panel discussions, “investor speed dating,” and business matchmaking between various industry stakeholders. Online registration for the event is c...
Tags: Startups, Entrepreneurship, Trends, Tech, Software, Innovation, Healthcare Industry, Biotech, Detroit, Digital Health, Life Sciences, Healthtech, Southeast Michigan, National blog main, Detroit blog main, Detroit top stories


Metamoto’s Jeff Blackburn on AV Testing and Why Waymo Leads the Pack

In the development of self-driving cars, once a vehicle is ready for the validation stage, it’s not always practical or affordable to test them on open roads. Given the hundreds of different scenarios developers want autonomous vehicles to experience and react to—weather, traffic conditions, pedestrian activity, land markings, and more—simulation offers an alternative to on-road testing.At the M:Bility conference held in Dearborn a few weeks ago, Xconomy had an opportunity to chat with Metamoto...
Tags: Startups, Entrepreneurship, Trends, Tech, Software, Innovation, Automotive Industry, Detroit, Blackburn, Alphabet, University Of Michigan, Virginia Tech, Dearborn, Bility, Jeff Blackburn, National blog main


Lyft, Uber, and the Changing Disclosure Rules For Unicorn IPOs

When a much-watched tech company such as Lyft, Uber, or Pinterest files for an initial public stock offering, people eagerly scour the sudden trove of information that such a private business must finally disclose when it begins to offer shares to the general public, rather than only to sophisticated inside investors such as venture capital firms.For newly public company Lyft, (NASDAQ: LYFT) though, the IPO disclosure requirements were significantly lower than they would usually be for business...
Tags: Deals, Startups, Transportation, Mobile, Lyft, Uber, Hardware, Pinterest, Internet, Entrepreneurship, Ipo, Funding, San Francisco, Trends, Tech, Financial Crisis


Thwarting Opposition, Bristol Gets Shareholder OK for $74B Celgene Buyout

The early opposition has turned out to be just noise. Shareholders of Bristol-Myers Squibb today approved the pharma giant’s planned buyout of Celgene, paving the way for a deal that will create one of the largest biopharma organizations in the world, and send ripples throughout the sector. (NYSE: BMY) said Friday that more than 75 percent of its shareholders voted to approve the deal at a meeting on Friday. Some 98 percent (NASDAQ: CELG) of Celgene’s stockholders supported the deal, the compa...
Tags: Deals, New York, Trends, Merck, M&a, Life Sciences, Nyse, Celgene, Bristol-myers Squibb, National blog main, New York blog main, New York top stories, Seattle blog main, Seattle top stories, Boston blog main, National top stories


Roundup: MiSpringboard, Free QL Demo Day Help, DetroitEd411 & More

Let’s catch up on the latest startup and innovation news from around Michigan:—Birmingham-based Pairaphrase, a startup selling translation software that it says provides users more security and privacy than competing products, such as Google Translate, has won a grant from the state of Michigan. The company did not disclose the amount of the grant from the Business Accelerator Fund but said in a press release that it would use the new capital to conduct a third-party security audit and assessme...
Tags: Startups, Roundup, Entrepreneurship, Trends, Tech, Software, Facebook Messenger, Innovation, Michigan, Birmingham, Detroit, Google Translate, Startup Competition, Wayne State University, National blog main, Detroit blog main


VC Trends in 2019: More Money, Fewer Deals But Women Still Get Less

If you’ve been following venture capital trends, what you expected to happen in the first quarter of 2019 did: More money is being invested in fewer deals, and women founders still are getting less of it than men.Venture firms sent $32.6 billion into startups nationally during the first three months of 2019, the second largest amount for any quarter since at least 2006, according to data released overnight by PitchBook and the National Venture Capital Association. But that large sum came from o...
Tags: Deals, Startups, Lyft, Uber, Hardware, Entrepreneurship, Softbank, Funding, Women, Trends, Tech, Vc, Software, Physics, Pwc, Venture Capital


Global Detroit, U-M Team on Program to Boost Immigrant-Led Startups

The American Dream was once a fairly simple concept: The nation would welcome strivers from across the world and invite them to pull themselves up by their bootstraps, work hard, pay taxes, and become contributing citizens. However, immigration has become a highly charged political issue in the current era, making things more complicated.That’s one reason Global Detroit and the University of Michigan’s Economic Growth Institute have partnered on a program to help international student and immig...
Tags: Startups, Entrepreneurship, Immigration, Trends, Tech, Innovation, Brad Feld, Detroit, STEM education, International Students, Foundry Group, Duo Security, William Davidson Foundation, University of Massachusetts Boston, National blog main, Boston blog main


Bio Roundup: Gottlieb’s Goodbye, AACR Recap, Migraine Drug Fight & More

Scott Gottlieb’s last day as FDA commissioner is today. His resignation announcement last month surprised some, given the earlier denials about leaving. But after two years of commuting between Connecticut, where his family remained, and the FDA’s Maryland headquarters, he decided to step down from the agency.What will Gottlieb’s legacy be? His efforts to curb teen vaping comes to mind. Or maybe it’s regulation. While Gottlieb remained mindful of the FDA’s oversight role, he also tried to strea...
Tags: Deals, Startups, Maryland, Breast Cancer, Trends, Investing, Lung Cancer, Connecticut, Cigna, Venture Capital, Fda, National, Novartis, Pfizer, Biotech, Insulin


Lear to Acquire Seattle Connected Vehicle Tech Firm Xevo For $320M

Lear Corp., a Southfield, MI-based manufacturer of car seats, automotive electrical systems, and other products, announced Tuesday it has agreed to acquire Xevo, a Seattle-based developer of connected vehicle software, for $320 million.Lear (NYSE: LEA) has been in business for over a century, and says its products are used by nearly every major automaker. The company’s sales were $21.1 billion last year. Lear says it has about 169,000 employees across 257 locations in 39 countries.Xevo, in turn...
Tags: Deals, Startups, Cars, Trends, Tech, Software, M&a, Autos, Lea, Seattle, Connected Vehicles, Acquisitions, Southfield, Lear, Lear Corp, John Absmeier


After Scoring New Capital, Fifth Eye Prepares to Seek FDA Approval

Fifth Eye, an Ann Arbor-based medical software startup spun out of technology developed at the University of Michigan, today announced that it has raised $9 million in new investment capital, bringing its total venture backing to date to $11.5 million.The round was led by Arboretum Ventures and Cultivation Capital, with participation from Invest Michigan, U-M’s MINTS program, and a bevy of angel investors. Founder and CEO Jen Baird says Fifth Eye will use the new capital to complete clinical st...
Tags: Startups, Entrepreneurship, Funding, Trends, Vc, Software, Innovation, Venture Capital, Michigan, Fda, Detroit, Angel Investors, Healthtech, University Of Michigan, Ann Arbor, National blog main


FarmWise and Roush Partner to Develop Robots that Weed Farm Fields

We’ve heard a lot about autonomous cars over the past few years, but there are other applications for self-driving technology, including agriculture.Silicon Valley startup FarmWise this week announced a new partnership with Livonia, MI-based Roush, a legacy manufacturer and engineering services firm, to develop and test an autonomous machine that weeds row crops. FarmWise co-founder and chief technology officer Thomas Palomares declined to disclose the monetary value of the partnership.FarmWise...
Tags: Startups, Roundup, Entrepreneurship, Trends, Tech, Farming, Innovation, Agriculture, Silicon Valley, Autonomous Machines, Detroit, Herbicides, Self-driving, Roush, Livonia, National blog main


Bio Roundup: Amyloid Angst, NASH News, Brammer Bagged & More

A week after , the ripple effects are still being felt—and not just by Biogen, which lost billions of dollars in market value in a flash.We’ll kick off this week’s roundup with the aducanumab reaction, which includes plenty of thoughts about the future of the so-called “amyloid hypothesis” and what’s next for another Biogen Alzheimer’s drug that has had mixed results.We’ll also check in on the gene therapy deal spree, the big week in national healthcare policy, and the preparations several com...
Tags: Deals, Obamacare, Trends, Alzheimer's Disease, Affordable Care Act, National, Pfizer, Medicaid, Xarelto, Federal Trade Commission, Life Sciences, Bayer, Clinical Trials, Celgene, Gilead Sciences, Eisai


Lyft Raises $2.2B in IPO, Pegging Valuation at Over $24B

Investors eager to bet on the mobility industry’s future handed ride-hailing company Lyft $2.2 billion in new capital Thursday as the company completed an IPO that set its market capitalization at $24.3 billion, The New York Times reported.Lyft sold 30.8 million shares at $72 apiece, according to Renaissance Capital—the top of a new range that Lyft originally set at $62 to $68. The company was valued at $15.1 billion at the time of its last fundraising in mid-2018.Lyft’s pricey showing rivals A...
Tags: Deals, Startups, Mobile, Lyft, Uber, Hardware, Marketplace, Pinterest, Entertainment, Internet, Entrepreneurship, Funding, US, San Francisco, Trends, Tech


Roundup: QL Demo Day, Millendo Therapeutics, Strata Oncology, More

—Millendo Therapeutics, an Ann Arbor-based biopharmaceutical company developing treatments for rare diseases, has initiated a Phase 2b/3 clinical study investigating livoletide (AZP-531) in patients with Prader-Willi syndrome.The study will evaluate the safety and efficacy of the drug on food-related behaviors—primarily hyperphagia, the excessive hunger which is a hallmark of the disease—in Prader-Willi patients. The study, called Zephyr, aims to recruit 150 patients from up to 40 clinical site...
Tags: Startups, Europe, Roundup, Entrepreneurship, Funding, Trends, Tech, Vc, United States, Innovation, Venture Capital, Biotech, Detroit, University Of Michigan, Ann Arbor, National blog main


Tespo, With a New Office in Detroit, Offers “the Keurig of Vitamins”

Ted Mills spent the first part of his career in finance, eventually starting a investment fund for Manoj Bhargava, the Michigan-based founder of 5 Hour Energy, in 2008. After five years in that role, Mills says it was time to spread his wings.He wanted to bring high-quality supplements to customers’ homes in liquid format, because he says 40 percent of the population is averse to swallowing pills. “I looked at the supplements industry and I was fascinated,” he explains. “It was so fragmented, a...
Tags: Startups, Mobile, Apps, Entrepreneurship, Connected Devices, Trends, Tech, Vc, Software, Supplements, Innovation, Venture Capital, Michigan, Detroit, Mills, Hour Energy


New Accelerator Aims For Social Change With AR, VR, Gaming Startups

Games for Change, a non-profit that promotes the use of games and immersive technology for social good, is taking applications from startup teams for a new accelerator program it’s launching in New York City.New York-based Games for Change already encourages game and XR developers, by a variety of means, to build societal benefits into their designs. The organization, founded in 2004, holds an annual festival with demos, workshops, and training sessions, and also operates awards programs and st...
Tags: Startups, Games, Internet, Entrepreneurship, Funding, San Francisco, Trends, Tech, Web, It, Vc, Software, Innovation, Venture Capital, Virtual Reality, Berkshire Hathaway


Erie Hack Aims to Solve Lake’s Challenges with Tech-Driven Solutions

Even though Michigan is surrounded by one of the world’s most abundant sources of freshwater, it’s still plagued by water-related challenges, such as the Flint water crisis, high lead levels in the water at Detroit public schools, and PFAS contamination. And with the Trump administration looking to cut federal funding for Great Lakes water restoration by 90 percent in its latest budget proposal, one could argue the situation may grow more precarious.It’s with that in mind that six cities in the...
Tags: Startups, Entrepreneurship, Trends, Tech, Innovation, Michigan, Cleveland, Detroit, Water Pollution, Water Technology, Trump, Flint, Flint Water Crisis, NASA Glenn Research Center, Erie, Toledo OH


M:Bility Conference: Panel Talks Factors Fueling Future of AV Industry

At AutoWorld’s M:Bility conference in Dearborn, MI, this week, a wide variety of topics pertaining to the mobility industry and the development of driverless technology were covered in keynote and panel discussions, including mapping and sensors, artificial intelligence, automotive data, mobility-as-a-service, electrification, and 5G connectivity.However, running through all topics was a measure of caution as industry insiders worked to adjust expectations as to when fully autonomous (or nearly...
Tags: Startups, Uber, Entrepreneurship, Trends, Tech, Software, Electric Vehicles, Auto Industry, Innovation, Gm, Mobility, Detroit, Smart Cities, Boeing, Valeo, Bility


Bio Roundup: Golumbeski’s Legacy, CRISPR Moratorium, Rebate Week & More

While all eyes in the biopharmaceutical world are currently trained on Bristol-Myers Squibb’s proposal to buy Celgene for $74 billion, it wasn’t that long ago that another company’s gaze was fixed on the Summit, NJ, drug maker.In the early 2000s, before the FDA approved Celgene’s flagship multiple myeloma drug lenalidomide (Revlimid), Novartis (NYSE: NVS considered buying the company. It passed, unwilling to risk billions on an unapproved drug. Those details came from biopharma dealmaker George...
Tags: Deals, Startups, China, Ipo, Cancer, Trends, Investing, Merck, Colorectal Cancer, Multiple Sclerosis, Harvard University, Health Insurance, Astrazeneca, Center For Medicare And Medicaid Services, Fda, National


Topouzian Brings Economic Development Perspective to New MVCA Role

Ara Topouzian is a longtime Oakland County economic development official and a 2012 Kresge Artist Fellow recognized for his work playing a 76-string kanun harp in Armenian and world music bands. As of March 25, he’ll also be the new director of the Michigan Venture Capital Association, which works to advance the state’s VC ecosystem.Topouzian comes to the MVCA after six years of heading up the 700-member Troy Chamber of Commerce, where he says he worked to reinvent the organization and create p...
Tags: Startups, Entrepreneurship, Trends, Vc, Innovation, Venture Capital, Detroit, Economic Development, Oakland County, National blog main, Detroit blog main, Detroit top stories, Diversity and Inclusion, Michigan Venture Capital Association, MVCA, EntryPoint


Alchemie Snags NSF Grant to Develop AR Tools for Teaching Chemistry

Alchemie, a Troy, MI-based educational technology startup, has won another round of funding from the National Science Foundation (NSF) to develop 3D and augmented reality (AR) learning tools for teaching general chemistry.The funding, announced this week, is a $140,000 Technology Enhancement through Commercialization Partnerships extension to a Phase II SBIR (Small Business Innovation Research) grant focused on building game-based learning modules and assessment technology for organic chemistry...
Tags: Startups, Entrepreneurship, Funding, Trends, Tech, Vc, Software, Chemistry, Innovation, Venture Capital, Detroit, University Of Michigan, Georgia Tech, National Science Foundation, University of Washington, NSF


Meet the Companies in Backstage Capital’s Detroit Accelerator

Backstage Capital, a Los Angeles-based venture firm seeding early-stage companies led by women, people of color, and members of the LGBTQ community, has announced the details of its Detroit startup accelerator.Earlier this year, Backstage founder Arlan Hamilton announced the firm would host its first accelerators in four cities, including Detroit. The Motor City’s inclusion, unlike the other three cities, was determined by way of a public vote.Monica Wheat, founder and partner at Venture Cataly...
Tags: Startups, Microsoft, Entrepreneurship, Los Angeles, Trends, Tech, Vc, Software, Innovation, Venture Capital, Detroit, Mailchimp, National blog main, National top stories, Detroit blog main, Detroit top stories


The Life, Troubles, and Celgene Legacy of Deal Guru George Golumbeski

George Golumbeski is one of the most prolific dealmakers in the biopharmaceutical world. But the deal that changed his life is a pact he made with himself when he was ten years old.Playing with friends in front of his house in Hampton, VA, he watched his mother drag his dead-drunk father, a U.S. Air Force veteran who did a short stint in Vietnam, out of his car. Pretending to sleep in his bedroom, he’d often hear his parents screaming at each other.“I can’t end up like this,” he remembers think...
Tags: Deals, Ipo, Events, Trends, People, Depression, National, Novartis, Vietnam, Biotech, Illumina, New Enterprise Associates, Life Sciences, University Of Wisconsin, Genentech, UCB


Roundup: Personnel Moves, MedHealth Summit, Genomenon, TechTown, More

Let’s catch up on news from around Michigan’s innovation clusters:—Ara Topouzian as been named the new executive director of the nonprofit Michigan Venture Capital Association (MVCA). Topouzian comes to the organization after a nearly six-year stint as CEO and president of the Troy Chamber of Commerce. Former MVCA director Maureen Miller Brosnan left the organization at the end of 2018 to pursue new opportunities, reports Crain’s Detroit Business. Topouzian will officially begin leading the org...
Tags: Startups, Roundup, Entrepreneurship, Trends, Intel, Innovation, Michigan, Detroit, Crain, National blog main, Detroit blog main, Detroit top stories, TechTown Detroit, Marlo Rencher, Genomenon, Maureen Miller Brosnan


Steering Lyft’s IPO: What Investors Will Weigh During the Roadshow

Much has been said about Lyft’s early lead over Uber in the “horserace” to become the first ride-hailing app company to go public. But now that San Francisco-based Lyft has filed its 276-page IPO prospectus with the U.S. Securities and Exchange Commission, potential investors can focus on much more detailed considerations as they decide whether to make bets on the smaller of the two U.S. ride-hailing leaders. Lyft’s IPO roadshow, during which it will make pitches to stock market investors and a...
Tags: Google, Startups, Mobile, Facebook, Lyft, Uber, Entrepreneurship, Wall Street, Funding, San Francisco, Trends, Tech, Regulations, IPOs, Vc, Software


Intel Reveals Ideas on Promoting AI in U.S. as Chinese Growth Looms

Even as the executive order President Trump issued last month on artificial intelligence furthered the conversation about a developing national strategy for the sector, it was met with certain criticism. A common complaint was that the plan won’t implement itself.“The administration’s American AI Initiative includes all of the right elements; the critical test will be to see if they follow through in a vigorous manner,” Jason Furman, who helped compile a report on AI for the Obama administratio...
Tags: Startups, Technology, Education, Obama, Climate Change, President Obama, Government, Immigration, San Francisco, Barack Obama, Trends, Startup, Tech, Legislation, Intel, IP


Retailers Turn to Analytics, 3D Tech to Promote Fit, Reduce Returns

One size fits most (at best), and a women’s sizing system created during the Depression doesn’t gibe in an e-commerce business that prizes personalization.That’s why startups are turning to new technologies like 3D scanning and machine learning software to produce customized clothing that can be made for the masses.“People want to buy a size,” says Patrick Donnelly, director of marketing at Fit3D, a San Mateo, CA-based maker of e-commerce software. “But we have the technology to make clothes fi...
Tags: Startups, Crowdfunding, Funding, Trends, Tech, Investment, E-commerce, People, Artificial Intelligence, Software, Innovation, Kickstarter, Machine Learning, National, Starbucks, 3D