Posts filtered by tags: Genetics[x]


Mixing human + animal DNA and the future of gene editing

As the material that makes all living things what/who we are, DNA is the key to understanding and changing the world. British geneticist Bryan Sykes and Francis Collins (director of the Human Genome Project) explain how, through gene editing, scientists can better treat illnesses, eradicate diseases, and revolutionize personalized medicine.But existing and developing gene editing technologies are not without controversies. A major point of debate deals with the idea that gene editing is overstep...
Tags: Family, Science, Biology, Animals, Dna, Genetics, Innovation, Disease, Human Genome Project, Bioethics, Cohen, Glenn Cohen, Francis Collins, Bryan Sykes

Want to live 100+ years? You may need unusually good DNA repair

Researchers conduct genetic analyses of 81 Italian people who are over 105 years in age. Five unusual genetic differences were discovered.The differences are implicated in the routine repair of DNA, which seems to work unusually well in these people.The oldest living person is Kane Tanaka of Fukuoka, Japan, who just celebrated her 116th birthday. The handful of people who live to be 105 years old or older are called "semi-supercentenarians." (Supercentenarians live to the ripe old age of 110 or...
Tags: Genetics, Chemistry, Medical Research, Italy, Innovation, University of Bologna, Fukuoka Japan, Martina Franca, Human body, University of Verona, Kane Tanaka, Claudio Franceschi, Paolo Garagnani, Massimo Delledonne

Doctors Discover Disease in Which People Can't Make Antibodies

In new research this month, doctors say they’ve discovered a new genetic disorder that saps a person’s ability to make antibodies. The likely very rare and treatable condition, first identified in a young boy from Philadelphia, may one day help scientists better understand the immune system.Read more...
Tags: Science, Immune System, Genetics, Philadelphia, Jack, Immunology, Antibodies, Clinical Medicine, Branches Of Biology, Medical Specialties, Health Medical Pharma, Immunodeficiency, Hypogammaglobulinemia, Neil Romberg, Luke Terrio, Gamma Globulin

Scientists launch search for genetic test to spot killer prostate cancer

Gene-screening, as is used to detect some breast cancer risks, could save thousands of livesScientists have begun work to create a prostate cancer screening service for the UK. In a few years, middle-aged men could be tested to reveal their genetic susceptibility to the condition, with those deemed to be under significant threat of developing it being offered treatment or surgery.The service would tackle a disease that has become the nation’s most commonly diagnosed cancer and would parallel Bri...
Tags: Health, UK, Science, Biology, Society, UK News, World news, Public services policy, Prostate Cancer, Genetics, Medical Research, Britain, Health policy, Men, Cancer Research

Are lab–grown embryos and human hybrids ethical?

In Aldous Huxley's 1932 novel “Brave New World," people aren't born from a mother's womb. Instead, embryos are grown in artificial wombs until they are brought into the world, a process called ectogenesis. In the novel, technicians in charge of the hatcheries manipulate the nutrients they give the fetuses to make the newborns fit the desires of society. Two recent scientific developments suggest that Huxley's imagined world of functionally manufactured people is no longer far-fetched.On March 17...
Tags: Biology, Animals, Genetics, Innovation, Philosophy, Morality, Bioethics, Aldous Huxley, Huxley, He Jiankui

Mass Extinction, Peopling Of America, Tale Of The Horse

 Sharing some interesting items:1) What was the impact of Deccan Volcanism on the end-Cretaceous mass extinction? Improved dating of the timing of volcanism shows that volcanism spanned the mass extinction. But what changes occurred to marine environments because of the outgassing wasn't well documented. A new study uses the oxygen isotope ratios in foraminifera shells to estimate ocean temperature changes before and after the mass extinction. The finding is that the oceans warmed well before th...
Tags: Books, India, Americas, Seo, History, Genetics, Central Asia, Chandra, Deccan Volcanics, Mass Extinction, Suvrat Kher, Jennifer Raff, Mini Menon, Joshua Sokol, Genomes Reveal Humanity 's Journey, Yashaswini Chandra

A patient’s perspective on genetic testing

I was sitting in a cold hospital room next to my husband, anxiously clutching his hand. The genetic counselor across from us withdrew a piece of paper from a white envelope and placed it on the table. She knew we were anxious to hear the results, so she got right to the point. “You have […] Find jobs at Careers by Search thousands of physician, PA, NP, and CRNA jobs now. Learn more.
Tags: Health, Genetics, Patient, PA NP, CRNA

Discovered: A tiny, glowing, poisonous, singing toadlet

A new species of "pumpkin toadlet" is discovered skittering along the forest floor in Brazil. It's highly poisonous and brightly colored, and some if its bones glow under UV light.An analysis of the toadlets' chirp song helped scientists establish that it's something new.It's tiny, just a little bigger than a thumbnail. It's partially fluorescent. It's orange. And it's very poisonous. Led by herpetologist Ivan Nunes, scientists have reported in the journal PLOS ONE the discovery of a new "pumpk...
Tags: Animals, Discovery, Genetics, Atlantic, Innovation, Brazil, Biodiversity, Toad, PLOS ONE, Smithsonian Magazine, Nunes, Biosphere, Ivan Nunes, Mantiqueira, Elise Laura K Rotenberg

Blame evolution for human disease

A new essay suggests that evolution both dooms us to certain diseases and provides ways to help improve medical care. Technology like polygenic risk scores already allow us to use genetics to predict and improve health outcomes.Future treatment options may begin with a review of your genetics.For every great evolutionary innovation, there is a new way for things to go wrong. Multicellularity allowed for more complex organisms, but those organisms became susceptible to cancer. The evolution of a...
Tags: Medicine, Genetics, Innovation, Disease, Evolution, Baylor University, Mary Benton, Benton, Human body, Baylor University News Service

Researchers identify genes linked to severe repetitive behaviors

Extreme repetitive behaviors such as hand-flapping, body-rocking, skin-picking, and sniffing are common to a number of brain disorders including autism, schizophrenia, Huntington's disease, and drug addiction. These behaviors, termed stereotypies, are also apparent in animal models of drug addiction and autism.In a new study published in the European Journal of Neuroscience, researchers at the McGovern Institute for Brain Research have identified genes that are activated in the brain prior to th...
Tags: Neuroscience, Mit, Mental Health, Brain, Genetics, Innovation, Mind, HUNTINGTON, Stanley Center for Psychiatric Research, Crittenden, McGovern Institute for Brain Research, McGovern Institute, Neuregulin, Ann Graybiel, Graybiel, MIT News Read

Tarantulas: How 120-million-year-old creatures conquered the globe

Scary-looking tarantulas actually prefer to keep to themselves and stay in their burrows. Their sedentary nature makes a puzzle of their presence in so many places around the world.Researchers discover that this is because they've been around a very long time and rode drifting continental land masses to their contemporary positions.Whenever a movie script calls for the protagonist to be menaced by a spider, central casting typically places a call to a tarantula wrangler. Tarantulas, or therapho...
Tags: Asia, Germany, Animals, Singapore, India, Americas, History, Genetics, Geology, Innovation, Carnegie Mellon University, Foley, Gondwana, Yale NUS College, Ancient World, Tarantulas

The “warrior gene”: blaming genetics for bad behavior

The extent to which we can blame our genes for bad behavior took another step backward recently, in the US at least, with a court ruling that data from the “warrior gene” couldn’t be used as an excuse for diminished responsibility.Belief in the existence of a warrior gene has been around for more than 25 years, one of many examples where genetic effects on behavior have been misunderstood. In 1994, Stephen Mobley, convicted of murder, armed robbery, aggravated assault, and possession of a firear...
Tags: Books, UK, Featured, US, Genetics, Tennessee, Netherlands, Ohio, Behaviour, Sanders, Brunner, New Mexico Supreme Court, Mobley, Science & Medicine, Psychology & Neuroscience, MAOA

CRISPR: Can we control it?

CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a revolutionary technology that gives scientists the ability to alter DNA. On the one hand, this tool could mean the elimination of certain diseases. On the other, there are concerns (both ethical and practical) about its misuse and the yet-unknown consequences of such experimentation."The technique could be misused in horrible ways," says counter-terrorism expert Richard A. Clarke. Clarke lists biological weapons as one of th...
Tags: Science, Biology, Genetics, Innovation, Richard Dawkins, Adolf Hitler, Crispr, Steven Pinker, Jennifer Doudna, Human body, Richard A Clarke Clarke, Doudna Clarke

What are the new Covid variants and what do they mean for the pandemic?

From Doug to Nelly and Eeek, we look at how mutations are affecting the battle against the virusCoronavirus – latest updatesSee all our coronavirus coverageFrom the moment public health officials started to track new variants of coronavirus, it became clear that the same mutations were cropping up time and again and making the virus more troublesome. What are these mutations, what do they do, and what do they mean for the pandemic? Continue reading...
Tags: Health, Science, World news, Genetics, Infectious Diseases, Doug, Nelly, Coronavirus

A genetic link between your face and brain shape

Studies have revealed a relationship between the shapes of the brain and face, but the nature of this relationship has remained poorly understood.In a recent study, researchers used 3D facial images, genetic data, and MRIs to identify genetic regions responsible for shaping both the brain and face.The results revealed a much more complex face-brain relationship than previously understood, though they don't suggest that facial structure can be used to predict intelligence or behavior.Scientists h...
Tags: UK, Brain, Genetics, Innovation, Belgium, Stanford University, Nature Genetics, Katholieke Universiteit Leuven, Peter Claes, Joanna Wysocka, Biobank, Human body, Stanford Medicine News Center, Laboratory for Imaging Genetics, Wysocka, Stanford Medicine News Center Many

Genetic research has a whiteness bias. H3Africa is trying to fix it

African DNA is grossly underrepresented in genetic research, but a number of organizations have sprung up to address the problem.
Tags: Science, Biology, Dna, Trends, Features, Genetics, Dei

Why do these rabbits do handstands and walk on their front paws instead of hopping?

Sauteur d'Alfort, a breed of domesticated rabbits, do "handstands" and walk on their front paws instead of hopping. New research suggest the strange behavior is likely caused by a mutation in a gene linked to limb movement. Understanding the mutation could help scientists better understand movement and the workings of the spinal cord in many other animals, including humans. — Read the rest
Tags: Video, Science, News, Animals, Genetics, Silly Rabbit, Alfort

Progeria: New treatment could extend lives of children with 'premature aging' syndrome

Progeria is an "accelerated aging" disease that causes children to die of "old age" at around 13 to 15 years.There are only two existing treatments, and both have unpleasant side effects.A promising new therapy based on biotechnology increases the lifespan of mice by over 60% and is ready for human clinical trials.Progeria is an extremely rare genetic disorder that causes children to present with symptoms that resemble "accelerated aging." A child with the condition takes on the appearance of an...
Tags: Biology, Genetics, Medical Research, Innovation, Disease, National Institutes of Health, Erdos, Hutchinson, Francis Collins, LMNA, Gilford, Hutchinson Gilford, Genomics Education Programme, Michael R Erdos, Michael Erdos

‘Zombie’ genes in the brain get to work after you die

While most brain cells do nothing or quickly degrade at death, others swing into high gear, sprouting long arms.While you're alive, the cells are involved in inflammation.Over the course of 24 hours after death, they get busier and busier. As bioethicist L. Syd M Johnson of SUNY-Upstate Medical University tells Big Think, "Death is not an event — it's a process." It's not as if there's a big on/off switch that gets flipped. It takes a while for a body's systems to wind down and eventually cease...
Tags: Death, Neuroscience, Discovery, Brain, Genetics, Medical Research, Innovation, Zombie, Loeb, UIC, SUNY Upstate Medical University, Syd M Johnson, Jeffrey Loeb, University of Illinois Chicago UIC, John S Garvin, UIC s College of Medicine

With Lynch Syndrome, knowledge alone isn’t power

“The blood test shows a genetic mutation at MLH1. You have Lynch.” The words were spoken by my genetic counselor the minute I sat in my chair should have hit me harder, but I only felt numb. I glanced at my closest friend, the person they had insisted go with me to the appointment, and […] Find jobs at Careers by Search thousands of physician, PA, NP, and CRNA jobs now. Learn more.
Tags: Health, Genetics, Conditions, Gastroenterology, PA NP, CRNA

What price a child's life? India's quest to make rare disease drugs affordable

Parents whose only hope was finding foreign sponsorship or a clinical trial are now looking for homegrown breakthroughsFor three years, Vidya tried to find the cause of her son’s recurrent fevers and low cognitive development. When she found out, she was devastated.Vineeth, 10, has an incurable illness – mucopolysaccharidosis type 2 – that affects his organs. Afflicting just one in a million, the enzyme-replacement medication that can help stop the illness getting any worse costs £100,000 a year...
Tags: Health, Business, Science, Biology, India, Society, World news, Genetics, Medical Research, South and Central Asia, Global development, Pharmaceuticals industry, Vidya, Global Health, Children's Health

Humans still similar to first animals without heads, arms or skeletons

A new study finds genetic links between early oceanic animals and humans. The animals studied had no heads, skeletons, legs or arms.The creatures were from the Ediacaran era, living about 555 million years ago. As complex as modern humans can get, they still retain some features of the earliest animals on Earth, found new research. We are not as different as we might think from strange prehistoric organisms that didn't have any heads, arms, legs or skeletons.A study from UC Riverside identified...
Tags: Biology, Animals, History, Earth, Genetics, Geology, Innovation, Evolution, Evans, Paleontology, UC Riverside, National Museum of Natural History, Ikaria, Scott Evans, Human body, Dickinsonia

An 'indiscriminate' massacre: Study examines why 41 people were killed 6,200 years ago

In 2007, a mass grave containing the ancient remains of 41 men, women, and children was discovered in Croatia.Initially, some researchers proposed the victims might have been killed due to xenophobia.However, a new genetic analysis suggests that the victims weren't newcomers to the area, leading researchers to note that climatic changes might have played a role in the killings. In 2007, a man in Potočani, Croatia, was digging a foundation for a garage when he discovered a grisly scene: the 6,2...
Tags: Climate Change, History, Genetics, Innovation, Anthropology, Croatia, Violence, Zagreb Croatia, Novak, Mario Novak, Institute for Anthropological Research

Kathleen Folbigg: how genetics could lead to a pardon for 'Australia's worst female serial killer'

She has always maintained her four children died of natural causes. Now 90 scientists argue she may be rightLeading scientific experts are petitioning for the pardon of the woman dubbed Australia’s worst female serial killer, arguing that all four of her children had rare genetic conditions that could explain their deaths.Kathleen Folbigg is in jail for killing her children as infants between 1990 and 1999. Continue reading...
Tags: Science, Australia, Australia news, Genetics, Crime - Australia, Law (Australia, Kathleen Folbigg

Your genetics influence how resilient you are to the cold

Some people just aren't bothered by the cold, no matter how low the temperature dips. And the reason for this may be in a person's genes. Our new research shows that a common genetic variant in the skeletal muscle gene, ACTN3, makes people more resilient to cold temperatures.Around one in five people lack a muscle protein called alpha-actinin-3 due to a single genetic change in the ACTN3 gene. The absence of alpha-actinin-3 became more common as some modern humans migrated out of Africa and into...
Tags: Asia, Europe, Weather, Biology, Australia, Dna, Africa, Genetics, Innovation, Lithuania, Duchenne, Kaunas, Lithuania Sweden, Human body, Peter John Houweling

Lab-grown brain organoids mature like real infant brains

Scientists have found that cultures of embryonic brain cells mature at the same rate as a 20-month-old infant's.Researchers have looked to such cell structures, called "organoids," as potential models for understanding the human body's biological mechanisms.Their study validates the use of lab-dish organoids for research. Scientists have been growing cell cultures that resemble natural human cells in dishes for a while now, but their usefulness for research has been inhibited by concerns that t...
Tags: Biology, Stanford, Neuroscience, Discovery, Brain, Genetics, Medical Research, Innovation, Ucla, Aaron Gordon, Geschwind, Organoids, Daniel Geschwind

After the Nobel, what next for Crispr gene-editing therapies?

Hailed as the ‘molecular scissors’ that will allow us to rewrite our genes, the DNA tool is being trialled in treatments for everything from sickle-cell anaemia to cancerWhen last year’s Nobel prize for chemistry was awarded to biochemist Jennifer Doudna and microbiologist Emmanuelle Charpentier for their work in developing the technique of gene editing known as Crispr-Cas9 (pronounced “crisper”), headlines hailed their discovery as “molecular scissors” that would allow us to “rewrite the book o...
Tags: Science, Biology, Cancer, Genetics, Medical Research, Crispr, Jennifer Doudna, Gene Editing, Emmanuelle Charpentier, Doudna, Sickle Cell Disease, Huntington's Disease, University of California at Berkeley Continue

Record for oldest DNA ever sequenced broken by mammoth remains

Scientists extracting DNA from mammoth teeth have set a new record for the oldest DNA ever sequenced. The new record holder may also be a member of a new species of mammoth, but that remains to be proven. The findings suggest that DNA as old as 2.6 million years old could be decoded. Analysis of million-year-old mammoth remains has set a new record for the oldest DNA ever sequenced and revealed a potentially new mammoth species. The study containing these findings, published in Nature, sheds n...
Tags: Animals, Genetics, Nature, Innovation, Evolution, Siberia, Columbia, Eurasia, Paleontology, Ludovic Orlando, Krestovka, Chukochya, Deextiction, Krestovka Adycha

Million-year-old mammoth genomes set record for ancient DNA

DNA from teeth found in Siberia permafrost the oldest yet sequenced, pushing science into ‘deep time’ Teeth from mammoths buried in the Siberian permafrost for more than a million years have led to the world’s oldest known DNA being sequenced, according to a study that shines a genetic searchlight on the deep past.Researchers said the three teeth specimens, one roughly 800,000 years old and two more than a million years old, provided important insights into the giant ice age mammals, including i...
Tags: Science, Sweden, Biology, Climate Change, Russia, World news, Genetics, Arctic, Evolution, Siberia, Palaeontology, Research publishing

From mammoth teeth, scientists just pulled DNA that's more than 1 million years old - the oldest DNA ever found

An illustration of steppe mammoths, ancestors of woolly mammoths, based on newly sequenced DNA from teeth found in Siberia. Beth Zaiken/Centre for Palaeogenetics Scientists sequenced DNA from three ancient mammoth teeth found in Siberia. Some of the DNA was more than 1 million years old, making it the oldest DNA ever recovered. Genetics reveal these mammoths to be ancestors of both woolly mammoths and the mammoths that later occupied North America. Visit the Business section of Insider for...
Tags: Science, News, Sweden, Dna, Trends, Genetics, Anthropology, Siberia, North America, Fossils, University Of Illinois, Wrangel Island, Urbana Champaign, Roca, Stockholm University, Sher