Posts filtered by tags: National Cancer Institute NCI[x]


Cancer-Related Internet Use and Its Association With Patient Decision Making and Trust in Physicians Among Patients in an Early Drug Development Clinic: A Questionnaire-Based Cross-Sectional Observational Study

Background: The role of cancer-related internet use on the patient-physician relationship has not been adequately explored among patients who are cancer-related internet users (CIUs) in early-phase clinical trial clinics. Objective: We examined the association between cancer-related internet use and the patient-physician relationship and decision making among CIUs in an early drug development clinic. Methods: Of 291 Phase I clinic patients who completed a questionnaire on internet use, 179 were ...
Tags: Health, US, National Cancer Institute NCI, NCI, Mann Whitney, Wilcoxon

Study finds elevated risk of rare blood cancers after chemotherapy for most solid tumors

Findings from a new study by researchers at the National Cancer Institute (NCI) show that patients treated with chemotherapy for most solid tumors during 2000-2014 experienced an increased risk of therapy-related myelodysplastic syndrome/acute myeloid leukemia (tMDS/AML). The study was published December 20, 2018, in JAMA Oncology. NCI is part of the National Institutes of Health.
Tags: AML, National Cancer Institute NCI, JAMA Oncology NCI

New approach to immunotherapy leads to complete response in breast cancer patient

A novel approach to immunotherapy developed by researchers at the National Cancer Institute (NCI) has led to the complete regression of breast cancer in a patient who was unresponsive to all other treatments. This patient received the treatment in a clinical trial led by Steven A. Rosenberg, M.D., Ph.D., chief of the Surgery Branch at NCI's Center for Cancer Research (CCR), and the findings were published June 4, 2018 in Nature Medicine.
Tags: Science, National Cancer Institute NCI, NCI, Center for Cancer Research CCR, Steven A Rosenberg

Realogy Earns CEO Cancer Gold Standard Accreditation for Seventh Consecutive Year

Madison, NJ – May 30, 2018 (PRNewswire) Realogy Holdings Corp. (NYSE: RLGY), the largest full-service residential real estate services company in the United States, announced that for the seventh consecutive year the Company earned CEO Cancer Gold Standard™ accreditation. Realogy was re-accredited for its dedication to making wellness an integral part of the Company’s culture, and satisfying the latest, comprehensive requirements of the Gold Standard. “We are excited to be recognized by the CEO...
Tags: Real Estate, Cancer, Radio, United States, Award, Company, Sotheby s International Realty, George H W Bush, National Cancer Institute, Real Estate News, National Cancer Institute NCI, Realogy, Realogy Holdings Corp NYSE, Better Homes and Gardens ® Real Estate CENTURY, Corcoran Group, Madison New Jersey

Cleveland Clinic researcher wins NCI grant to delve into cancer genetics and radiation effectiveness

Can the genetic makeup of their cancers predict how patients with lung cancer will respond to radiation therapy? And can this information be used to advance a genetically guided strategy for patients with these tumors? Cleveland Clinic researcher and radiation oncologist Mohamed Abazeed, M.D., Ph.D., has been awarded a $2 million grant from the National Cancer Institute (NCI) to delve into those and other related questions.
Tags: Health, Cleveland Clinic, National Cancer Institute NCI, NCI, Mohamed Abazeed

New 'Pan-Cancer' analysis reveals the common roots of different cancers

Cancer researchers have released the results of a comprehensive analysis of genomic and molecular data characterizing 33 different types of cancer from more than 10,000 patients. Called the Pan-Cancer Atlas, it is the most comprehensive cross-cancer analysis to date and is the final output of The Cancer Genome Atlas (TCGA) program, a joint effort of the National Cancer Institute (NCI) and the National Human Genome Research Institute (NHGRI).
Tags: National Cancer Institute NCI

SOM's net-zero Paris skyscraper will be one of the most sustainable buildings in Europe

Prolific firm Skidmore, Owings and Merrill (SOM) just unveiled plans for Charenton-Bercy, a net-zero Paris skyscraper that’s designed to be one of the most sustainable buildings in Europe. The 180-meter tower would include multiple green features, including rainwater harvesting, greywater recycling, green roofs, and waste-to-energy conversion systems. As part of its “garden in the sky” design, the project would also feature a band of vegetation running the length of the tower’s facade, leading ...
Tags: Europe, Design, Egypt, Paris, Seine, Som, National Cancer Institute NCI, Skidmore Owings, Merrill SOM, Charenton Bercy, Daniel Ringelstein, SOM London

Tisch Cancer Institute Director Ramon Parsons Awarded $6.7 Million for Research on Cancer-Causing Gene Mutated in Cancers with the Least Treatment Options

The National Cancer Institute (NCI) has awarded Ramon Parsons, MD, PhD, the prestigious Outstanding Investigator Award, granting him $6.7 million over seven years for research into the tumor-suppressing functions of the PTEN gene, which he discovered.
Tags: Science, National Cancer Institute NCI, Tisch Cancer Institute, PTEN, Ramon Parsons

NCI study shows feasibility of cancer screening protocol for Li-Fraumeni syndrome patients

In a new study from the National Cancer Institute (NCI), part of the National Institutes of Health, researchers found a higher than expected prevalence of cancer at baseline screening in individuals with Li-Fraumeni syndrome (LFS), a rare inherited disorder that leads to a higher risk of developing certain cancers. The research demonstrates the feasibility of a new, comprehensive cancer screening protocol for this high-risk population.
Tags: Science, National Institutes of Health, LFS, National Cancer Institute NCI, NCI, Li Fraumeni

Common insurance plans leave care at America's top cancer hospitals out of reach

Cancer patients in the United States may be unable to access care at the nation's top hospitals due to narrow insurance plan coverage -- leaving patients to choose between lower premiums or access to higher-quality cancer care. A new study from the Perelman School of Medicine at the University of Pennsylvania shows common, so-called 'narrow network' insurance plans -- lower-premium plans with reduced access to certain providers -- are more likely to exclude doctors associated with National Cance...
Tags: Science, America, United States, National Cancer Institute NCI

Four Dana-Farber Researchers Awarded Prestigious "Outstanding Investigator Awards" by National Cancer Institute

The National Cancer Institute (NCI) has awarded four Dana-Farber Cancer Institute researchers with Outstanding Investigator Awards (OIA) for ongoing progressive research within their respective areas of study.
Tags: Science, Oia, Dana Farber Cancer Institute, National Cancer Institute, Dana Farber, National Cancer Institute NCI

Worried That Grilling Will Give You Cancer? Here Are Some Safeguards You Can Take

With most of the country ready to fire up their grills for Memorial Day, you might be worrying about all those cancer claims surrounding grilled foods. Before we partake in a weekend of charred burgers, seared steaks and other grilled meals, let’s look into this a little more closely.  Why is there cancer risk associated with grilled foods? The reason there is concern revolving around grilled food, mostly meat, has to do with two compounds that are both known carcinogens: heterocyclic amines ...
Tags: Cook, News, Huffington Post, Julie R Thomson, HCA, National Cancer Institute NCI, NCI, American Cancer Society ACS, Colleen Doyle, Doyle Marinating

Ready for Launch: Selecta Biosciences Inc. Jumps as Much as 16%

Shares of Selecta Biosciences (NASDAQ: SELB) , a clinical-stage biotech company focused on developing proprietary gene therapies to improve patient tolerance to treatments, rocketed higher by as much as 16% during Monday's trading session after the company announced an experimental compound licensing deal with the National Cancer Institute (NCI).According to today's press release, Selecta Biosciences is in-licensing LMB-100, a next-generation immunotoxin from the Center for Cancer Research (CCR...
Tags: Finance, Health Care, Sean Williams, National Cancer Institute NCI, NCI, Selecta, 10% Promise, LMB, SELB, 6e4fe314-2f73-11e7-a413-0050569d4be0, Selecta Biosciences Inc Jumps, Selecta Biosciences NASDAQ, Selecta Biosciences, Center for Cancer Research CCR, Synthetic Vaccine Particle SVP

Cancer burden for aging US HIV population projected to shift

In findings presented at the 2017 American Association for Cancer Research Annual Meeting on April 5, a UNC-Chapel Hill researcher, in collaboration with the National Cancer Institute (NCI) and Centers for Disease Control and Prevention (CDC), reports the total number of HIV-positive cancer patients in the United States is projected to decrease through 2030. They also expect to see a shift in the types of cancers seen in the population.
Tags: Science, US, United States, UNC Chapel Hill, Centers for Disease Control and Prevention CDC, National Cancer Institute NCI

Major grant funds research effort that seeks to understand complexity of invasive cancer

A $9.5 million, five-year grant from the National Cancer Institute (NCI) will fund an intensive multidisciplinary research effort that seeks to better understand how cancer cells reach an aggressive state and begin to damage surrounding tissue.
Tags: Health, National Cancer Institute NCI

MD Anderson and nation's cancer centers jointly endorse updated HPV vaccine recommendations

As national vaccination rates for the human papillomavirus (HPV) remain low, The University of Texas MD Anderson Cancer Center has again united with the 68 other National Cancer Institute (NCI)-designated cancer centers in issuing a joint statement endorsing the recently revised vaccination recommendations from the Centers for Disease Control and Prevention (CDC).
Tags: Science, Anderson, University of Texas MD Anderson Cancer Center, National Cancer Institute NCI

Cellular immunotherapy targets a common human cancer mutation

In a study of an immune therapy for colorectal cancer that involved a single patient, a team of researchers at the National Cancer Institute (NCI) identified a method for targeting the...
Tags: Cancer / Oncology, National Cancer Institute NCI

National Cancer Institute Awards Major Contract to Southern Research

/PRNewswire-USNewswire/ -- Southern Research has been awarded a new, five-year Indefinite-Delivery Indefinite-Quantity (IDIQ) contract from the National Cancer Institute (NCI) to investigate the pharmacokinetic properties of antitumor and other therapeutic agents of interest to the Division of Cancer Treatment and Diagnosis (DCTD) under NCI contract HHSN261201600021I. RFP number N02CM67000-11 was issued under full and open competition, which resulted in five IDIQ awards. Task orders will be comp...
Tags: Science, National Cancer Institute NCI, NCI

Risk factors for prostate cancer aren't what we think, SWOG study shows

When it comes to prostate cancer biopsies, risk and reality don't always match up, according to research published today in the Journal of Clinical Oncology. Investigators from SWOG, the cancer clinical trials network funded by the National Cancer Institute (NCI), found widespread detection bias after a fresh examination of data from the two largest US prostate cancer prevention trials. The research is the first systematic review of bias in prostate cancer biopsy patterns.
Tags: Science, US, National Cancer Institute NCI

How Routing Mammography Screening Leads To Overdiagnosis And Overtreatment

Around 40,000 individual women die of breast cancer each and every year. Sisters. Mothers. Daughters. Spouses. Friends. For each of these women and their loved ones breast cancer is a personal tragedy. Breast cancer is also a public health crisis and social justice issue. Despite decades of awareness campaigns, breast cancer is the second leading cause of cancer death for women in the U.S. And a woman's chances of surviving a diagnosis are significantly impacted by her race, as well as socioecon...
Tags: News, British Medical Journal, Huffington Post, Dartmouth College, New England Journal of Medicine, American Cancer Society, JAMA, National Cancer Institute, National Cancer Institute NCI, Karuna Jaggar

Disaster aftermath: Helping people to ensure Medicare benefits continue

Photo: Eric Hackathorn via Flickr Hurricane Matthew wreaked havoc on the south east United States. It left at least 43 people dead and forced many from their homes, due to rising rivers that flooded many communities. In parts of North Carolina, the storm was particularly cruel to lower income residents, reported The Washington Post. Disasters like this may be hardest on older residents – who may not drive, have serious chronic health conditions or mobility problems. Older people who were forc...
Tags: Health, Aging, Disaster, Hurricane, Social Security, Medicare, North Carolina, Medicare Advantage, National Cancer Institute NCI, Social determinants, ESRD

National Cancer Institute Awards Major Contract to Southern Research

Southern Research has been awarded a five-year IDIQ contract with a potential value of $19 million from the National Cancer Institute (NCI) to study the preclinical toxicology of new drugs that are under development for treatment of cancer.
Tags: Science, National Cancer Institute NCI, Southern Research

Fighting cancer with space research

For the past 15 years, the big data techniques pioneered by NASA's Jet Propulsion Laboratory in Pasadena, California, have been revolutionizing biomedical research. On Sept. 6, 2016, JPL and the National Cancer Institute (NCI), part of the National Institutes of Health, renewed a research partnership through 2021, extending the development of data science that originated in space exploration and is now supporting new cancer discoveries.
Tags: Nasa, National Institutes of Health, Jpl, Jet Propulsion Laboratory, Pasadena California, National Cancer Institute NCI

[Policy Forum] A U.S. “Cancer Moonshot” to accelerate cancer research

In January 2016 President Obama announced a “Cancer Moonshot” to “accelerate our understanding of cancer and its prevention, early detection, treatment, and cure” (1). A Blue Ribbon Panel (BRP) of scientific experts was convened to make recommendations to the National Cancer Advisory Board (NCAB), the adviser to the National Cancer Institute (NCI), on research opportunities uniquely poised for acceleration. These recommendations were presented on 7 September 2016 (2). As cochairs of the BRP, we ...
Tags: Science, Obama, National Cancer Institute NCI, BRP

10 Cancer Moonshot Blue Ribbon Panel recommendations embraced by NCI

When 28 distinguished individuals convened earlier this year to help shape the scientific mission at the National Cancer Institute (NCI) of Vice President Joe Biden's National Cancer Moonshot Initiative, they were given five months to draft guidelines to accelerate cancer research, prevention and care. On Wednesday, the National Cancer Advisory Board approved the Blue Ribbon Panel's 10 recommendations.
Tags: Joe Biden, National Cancer Institute NCI, NCI, Blue Ribbon Panel

University of Minnesota Awarded Multimillion-Dollar Grant for Physics-Based Approach to Cancer

The National Cancer Institute (NCI) awarded the University of Minnesota an $8.2 million Physical Sciences in Oncology Center (PS-OC) grant over the next five years to develop a cell migration simulator that will predict how cancer cells spread in the body leading to invasion and metastasis.
Tags: Science, University of Minnesota, National Cancer Institute NCI

Char None! Healthy Options For High Heat Cooking

I've never been much of a fried food fan but I love the crispy edges of burnt toast and pizza crust, seared salmon skin and grilled veggies. When I was a meat eater we'd always asked for the flavorful "burnt ends" of the barbecued brisket or pork butt. Grilling and barbecues are cooking rites of summer. But high heat and open flame cooking can cause a chemical reaction in the foods that are potentially carcinogenic. According to the National Cancer Institute (NCI): Heterocyclic amines (HCAs) and...
Tags: News, Worcester, Huffington Post, Caribbean, Kansas State University, HCA, National Cancer Institute NCI, NCI, Melanie Young

Clinical responses with T lymphocytes targeting malignancy-associated κ light chains

BACKGROUND. Treatment of B cell malignancies with adoptive transfer of T cells with a CD19-specific chimeric antigen receptor (CAR) shows remarkable clinical efficacy. However, long-term persistence of T cells targeting CD19, a pan–B cell marker, also depletes normal B cells and causes severe hypogammaglobulinemia. Here, we developed a strategy to target B cell malignancies more selectively by taking advantage of B cell light Ig chain restriction. We generated a CAR that is specific for the κ ...
Tags: NHL, Carlos, Hodgkin, National Cancer Institute NCI

New US data system to centralize cancer information

The US National Institutes of Health has announced the creation of a centralized data system to facilitate cancer research access and sharing. The Genomic Data Commons (GDC) will centralize, standardize and facilitate access to large-scale programs of the National Cancer Institute (NCI), such as The Cancer Genome Atlas -- which has mapped important genetic mutations for 33 types of cancer -- as well as its pediatric equivalent, Therapeutically Applicable Research to Generate Effective Treatments...
Tags: News, US, National Cancer Institute NCI, US National Institutes of Health

Study visualizes proteins involved in cancer cell metabolism

Scientists using a technology called cryo-EM (cryo-electron microscopy) have broken through a technological barrier in visualizing proteins with an approach that may have an impact on drug discovery and development. They were able to capture images of glutamate dehydrogenase, an enzyme found in cells, at a resolution of 1.8 angstroms, a level of detail at which the structure of the central parts of the enzyme could be visualized in atomic detail. The scientists from the National Cancer Institute...
Tags: National Institutes of Health, Biochemistry, National Cancer Institute NCI